Identity
HGNC
LOCATION
4q12
LOCUSID
ALIAS
BM-102,SEC3,SEC3L1,SEC3P
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 55763
MIM: 607879
HGNC: 30380
Ensembl: ENSG00000090989
Variants:
dbSNP: 55763
ClinVar: 55763
TCGA: ENSG00000090989
COSMIC: EXOC1
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 31495494 | 2019 | Sec3 knockdown inhibits TGF-β induced epithelial-mesenchymal transition through the down-regulation of Akt phosphorylation in A549 cells. | 1 |
| 31495494 | 2019 | Sec3 knockdown inhibits TGF-β induced epithelial-mesenchymal transition through the down-regulation of Akt phosphorylation in A549 cells. | 1 |
| 28694212 | 2017 | Role of rs13117307 single nuclear polymorphism in the risk of uterine cervical cancer from Polish population and its impact on exocyst complex component 1 expression. | 4 |
| 28694212 | 2017 | Role of rs13117307 single nuclear polymorphism in the risk of uterine cervical cancer from Polish population and its impact on exocyst complex component 1 expression. | 4 |
| 23522008 | 2013 | West Nile virus and dengue virus capsid protein negates the antiviral activity of human Sec3 protein through the proteasome pathway. | 16 |
| 23522008 | 2013 | West Nile virus and dengue virus capsid protein negates the antiviral activity of human Sec3 protein through the proteasome pathway. | 16 |
| 19889084 | 2010 | Human Sec3 protein is a novel transcriptional and translational repressor of flavivirus. | 10 |
| 19889837 | 2010 | Sec3-containing exocyst complex is required for desmosome assembly in mammalian epithelial cells. | 23 |
| 19889084 | 2010 | Human Sec3 protein is a novel transcriptional and translational repressor of flavivirus. | 10 |
| 19889837 | 2010 | Sec3-containing exocyst complex is required for desmosome assembly in mammalian epithelial cells. | 23 |
| 18541705 | 2008 | The interaction of IQGAP1 with the exocyst complex is required for tumor cell invasion downstream of Cdc42 and RhoA. | 160 |
| 18541705 | 2008 | The interaction of IQGAP1 with the exocyst complex is required for tumor cell invasion downstream of Cdc42 and RhoA. | 160 |
Citation
Dessen P
EXOC1 (exocyst complex component 1)
Atlas Genet Cytogenet Oncol Haematol. 2003-12-01
Online version: http://atlasgeneticsoncology.org/gene/42238/exoc1
