Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

EXOC3 (exocyst complex component 3)

Identity

Other namesSEC6
SEC6L1
Sec6p
HGNC (Hugo) EXOC3
LocusID (NCBI) 11336
Location 5p15.33
Location_base_pair Starts at 443334 and ends at 467409 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)EXOC3   30378
Cards
Entrez_Gene (NCBI)EXOC3  11336  exocyst complex component 3
GeneCards (Weizmann)EXOC3
Ensembl hg19 (Hinxton)ENSG00000180104 [Gene_View]  chr5:443334-467409 [Contig_View]  EXOC3 [Vega]
Ensembl hg38 (Hinxton)ENSG00000180104 [Gene_View]  chr5:443334-467409 [Contig_View]  EXOC3 [Vega]
ICGC DataPortalENSG00000180104
cBioPortalEXOC3
AceView (NCBI)EXOC3
Genatlas (Paris)EXOC3
WikiGenes11336
SOURCE (Princeton)EXOC3
Genomic and cartography
GoldenPath hg19 (UCSC)EXOC3  -     chr5:443334-467409 +  5p15.33   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)EXOC3  -     5p15.33   [Description]    (hg38-Dec_2013)
EnsemblEXOC3 - 5p15.33 [CytoView hg19]  EXOC3 - 5p15.33 [CytoView hg38]
Mapping of homologs : NCBIEXOC3 [Mapview hg19]  EXOC3 [Mapview hg38]
OMIM608186   
Gene and transcription
Genbank (Entrez)AA487875 AF055006 AI628051 AK074086 AK131103
RefSeq transcript (Entrez)NM_007277
RefSeq genomic (Entrez)AC_000137 NC_000005 NC_018916 NT_006576 NW_001838923 NW_004929321
Consensus coding sequences : CCDS (NCBI)EXOC3
Cluster EST : UnigeneHs.481464 [ NCBI ]
CGAP (NCI)Hs.481464
Alternative Splicing : Fast-db (Paris)GSHG0023726
Alternative Splicing GalleryENSG00000180104
Gene ExpressionEXOC3 [ NCBI-GEO ]     EXOC3 [ SEEK ]   EXOC3 [ MEM ]
SOURCE (Princeton)Expression in : [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO60645 (Uniprot)
NextProtO60645  [Medical]
With graphics : InterProO60645
Splice isoforms : SwissVarO60645 (Swissvar)
Domains : Interpro (EBI)Sec6   
Related proteins : CluSTrO60645
Domain families : Pfam (Sanger)Sec6 (PF06046)   
Domain families : Pfam (NCBI)pfam06046   
DMDM Disease mutations11336
Blocks (Seattle)O60645
Human Protein AtlasENSG00000180104
Peptide AtlasO60645
HPRD09738
IPIIPI00157734   IPI00219954   IPI00967947   IPI00966180   IPI00966432   
Protein Interaction databases
DIP (DOE-UCLA)O60645
IntAct (EBI)O60645
FunCoupENSG00000180104
BioGRIDEXOC3
IntegromeDBEXOC3
STRING (EMBL)EXOC3
Ontologies - Pathways
QuickGOO60645
Ontology : AmiGOexocyst  protein binding  exocytosis  protein transport  secretory granule membrane  cellular protein metabolic process  membrane organization  
Ontology : EGO-EBIexocyst  protein binding  exocytosis  protein transport  secretory granule membrane  cellular protein metabolic process  membrane organization  
Pathways : KEGGTight junction   
Protein Interaction DatabaseEXOC3
DoCM (Curated mutations)EXOC3
Wikipedia pathwaysEXOC3
Gene fusion - rearrangements
Polymorphisms : SNP, variants
NCBI Variation ViewerEXOC3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)EXOC3
dbVarEXOC3
ClinVarEXOC3
1000_GenomesEXOC3 
Exome Variant ServerEXOC3
SNP (GeneSNP Utah)EXOC3
SNP : HGBaseEXOC3
Genetic variants : HAPMAPEXOC3
Genomic VariantsEXOC3  EXOC3 [DGVbeta]
Mutations
ICGC Data PortalENSG00000180104 
Somatic Mutations in Cancer : COSMICEXOC3 
CONAN: Copy Number AnalysisEXOC3 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)5:443334-467409
Mutations and Diseases : HGMDEXOC3
OMIM608186   
MedgenEXOC3
NextProtO60645 [Medical]
GENETestsEXOC3
Disease Genetic AssociationEXOC3
Huge Navigator EXOC3 [HugePedia]  EXOC3 [HugeCancerGEM]
snp3D : Map Gene to Disease11336
DGIdb (Drug Gene Interaction db)EXOC3
General knowledge
Homologs : HomoloGeneEXOC3
Homology/Alignments : Family Browser (UCSC)EXOC3
Phylogenetic Trees/Animal Genes : TreeFamEXOC3
Chemical/Protein Interactions : CTD11336
Chemical/Pharm GKB GenePA134869816
Clinical trialEXOC3
Cancer Resource (Charite)ENSG00000180104
Other databases
Probes
Litterature
PubMed30 Pubmed reference(s) in Entrez
CoreMineEXOC3
GoPubMedEXOC3
iHOPEXOC3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2014Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sat Dec 20 21:25:28 CET 2014

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.