Atlas of Genetics and Cytogenetics in Oncology and Haematology


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EXOC7 (exocyst complex component 7)

Identity

Alias_symbol (synonym)EXO70
KIAA1067
YJL085W
Exo70p
Other alias2-5-3p
EX070
EXOC1
HGNC (Hugo) EXOC7
LocusID (NCBI) 23265
Atlas_Id 54294
Location 17q25.1  [Link to chromosome band 17q25]
Location_base_pair Starts at 76080993 and ends at 76103787 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
EXOC7 (17q25.1) / CYTH1 (17q25.3)EXOC7 (17q25.1) / EXOC7 (17q25.1)EXOC7 (17q25.1) / FOXJ1 (17q25.1)
EXOC7 (17q25.1) / GBA2 (9p13.3)EXOC7 (17q25.1) / MTDH (8q22.1)EXOC7 (17q25.1) / MYADM (19q13.42)
EXOC7 (17q25.1) / NAP1L1 (12q21.2)EXOC7 (17q25.1) / USP22 (17p11.2)EXOC7 17q25.1 / FOXJ1 17q25.1
EXOC7 17q25.1 / USP22 17p11.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)EXOC7   23214
Cards
Entrez_Gene (NCBI)EXOC7  23265  exocyst complex component 7
Aliases2-5-3p; EX070; EXO70; EXOC1; 
Exo70p; YJL085W
GeneCards (Weizmann)EXOC7
Ensembl hg19 (Hinxton)ENSG00000182473 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000182473 [Gene_View]  chr17:76080993-76103787 [Contig_View]  EXOC7 [Vega]
ICGC DataPortalENSG00000182473
TCGA cBioPortalEXOC7
AceView (NCBI)EXOC7
Genatlas (Paris)EXOC7
WikiGenes23265
SOURCE (Princeton)EXOC7
Genetics Home Reference (NIH)EXOC7
Genomic and cartography
GoldenPath hg38 (UCSC)EXOC7  -     chr17:76080993-76103787 -  17q25.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)EXOC7  -     17q25.1   [Description]    (hg19-Feb_2009)
EnsemblEXOC7 - 17q25.1 [CytoView hg19]  EXOC7 - 17q25.1 [CytoView hg38]
Mapping of homologs : NCBIEXOC7 [Mapview hg19]  EXOC7 [Mapview hg38]
OMIM608163   
Gene and transcription
Genbank (Entrez)AA215645 AB028990 AI565863 AI653861 AK000718
RefSeq transcript (Entrez)NM_001013839 NM_001145297 NM_001145298 NM_001145299 NM_001282313 NM_001282314 NM_015219
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)EXOC7
Cluster EST : UnigeneHs.514496 [ NCBI ]
CGAP (NCI)Hs.514496
Alternative Splicing GalleryENSG00000182473
Gene ExpressionEXOC7 [ NCBI-GEO ]   EXOC7 [ EBI - ARRAY_EXPRESS ]   EXOC7 [ SEEK ]   EXOC7 [ MEM ]
Gene Expression Viewer (FireBrowse)EXOC7 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)23265
GTEX Portal (Tissue expression)EXOC7
Human Protein AtlasENSG00000182473-EXOC7 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9UPT5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9UPT5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9UPT5
Splice isoforms : SwissVarQ9UPT5
PhosPhoSitePlusQ9UPT5
Domains : Interpro (EBI)Cullin_repeat-like_dom    Exo70   
Domain families : Pfam (Sanger)Exo70 (PF03081)   
Domain families : Pfam (NCBI)pfam03081   
Conserved Domain (NCBI)EXOC7
DMDM Disease mutations23265
Blocks (Seattle)EXOC7
SuperfamilyQ9UPT5
Human Protein Atlas [tissue]ENSG00000182473-EXOC7 [tissue]
Peptide AtlasQ9UPT5
HPRD16292
IPIIPI00172532   IPI00641168   IPI00103064   IPI00394717   IPI00879399   IPI00877965   IPI00470482   IPI00939554   IPI00386399   IPI00794992   
Protein Interaction databases
DIP (DOE-UCLA)Q9UPT5
IntAct (EBI)Q9UPT5
FunCoupENSG00000182473
BioGRIDEXOC7
STRING (EMBL)EXOC7
ZODIACEXOC7
Ontologies - Pathways
QuickGOQ9UPT5
Ontology : AmiGOexocyst  protein binding  microtubule organizing center  cytosol  plasma membrane  exocytosis  protein transport  membrane  regulation of macroautophagy  growth cone membrane  centriolar satellite  regulation of entry of bacterium into host cell  
Ontology : EGO-EBIexocyst  protein binding  microtubule organizing center  cytosol  plasma membrane  exocytosis  protein transport  membrane  regulation of macroautophagy  growth cone membrane  centriolar satellite  regulation of entry of bacterium into host cell  
Pathways : KEGGInsulin signaling pathway   
NDEx NetworkEXOC7
Atlas of Cancer Signalling NetworkEXOC7
Wikipedia pathwaysEXOC7
Orthology - Evolution
OrthoDB23265
GeneTree (enSembl)ENSG00000182473
Phylogenetic Trees/Animal Genes : TreeFamEXOC7
HOVERGENQ9UPT5
HOGENOMQ9UPT5
Homologs : HomoloGeneEXOC7
Homology/Alignments : Family Browser (UCSC)EXOC7
Gene fusions - Rearrangements
Fusion : MitelmanEXOC7/CYTH1 [17q25.1/17q25.3]  
Fusion : MitelmanEXOC7/FOXJ1 [17q25.1/17q25.1]  [t(17;17)(q25;q25)]  
Fusion : MitelmanEXOC7/USP22 [17q25.1/17p11.2]  [t(17;17)(p11;q25)]  
Fusion: TCGA_MDACCEXOC7 17q25.1 FOXJ1 17q25.1 LUAD
Fusion: TCGA_MDACCEXOC7 17q25.1 USP22 17p11.2 BRCA
Tumor Fusion PortalEXOC7
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerEXOC7 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)EXOC7
dbVarEXOC7
ClinVarEXOC7
1000_GenomesEXOC7 
Exome Variant ServerEXOC7
ExAC (Exome Aggregation Consortium)ENSG00000182473
GNOMAD BrowserENSG00000182473
Genetic variants : HAPMAP23265
Genomic Variants (DGV)EXOC7 [DGVbeta]
DECIPHEREXOC7 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisEXOC7 
Mutations
ICGC Data PortalEXOC7 
TCGA Data PortalEXOC7 
Broad Tumor PortalEXOC7
OASIS PortalEXOC7 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICEXOC7  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDEXOC7
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch EXOC7
DgiDB (Drug Gene Interaction Database)EXOC7
DoCM (Curated mutations)EXOC7 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)EXOC7 (select a term)
intoGenEXOC7
Cancer3DEXOC7(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM608163   
Orphanet
DisGeNETEXOC7
MedgenEXOC7
Genetic Testing Registry EXOC7
NextProtQ9UPT5 [Medical]
TSGene23265
GENETestsEXOC7
Target ValidationEXOC7
Huge Navigator EXOC7 [HugePedia]
snp3D : Map Gene to Disease23265
BioCentury BCIQEXOC7
ClinGenEXOC7
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD23265
Chemical/Pharm GKB GenePA134988420
Clinical trialEXOC7
Miscellaneous
canSAR (ICR)EXOC7 (select the gene name)
Probes
Litterature
PubMed44 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineEXOC7
EVEXEXOC7
GoPubMedEXOC7
iHOPEXOC7
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 14:12:28 CET 2017

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