Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

EXOSC9 (exosome component 9)

Identity

Alias_namesPMSCL1
polymyositis/scleroderma autoantigen 1, 75kDa
Alias_symbol (synonym)PM/Scl-75
Rrp45p
RRP45
p5
p6
Other alias
HGNC (Hugo) EXOSC9
LocusID (NCBI) 5393
Atlas_Id 62955
Location 4q27  [Link to chromosome band 4q27]
Location_base_pair Starts at 121801317 and ends at 121817021 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)EXOSC9   9137
Cards
Entrez_Gene (NCBI)EXOSC9  5393  exosome component 9
AliasesPM/Scl-75; PMSCL1; RRP45; Rrp45p; 
p5; p6
GeneCards (Weizmann)EXOSC9
Ensembl hg19 (Hinxton)ENSG00000123737 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000123737 [Gene_View]  chr4:121801317-121817021 [Contig_View]  EXOSC9 [Vega]
ICGC DataPortalENSG00000123737
TCGA cBioPortalEXOSC9
AceView (NCBI)EXOSC9
Genatlas (Paris)EXOSC9
WikiGenes5393
SOURCE (Princeton)EXOSC9
Genetics Home Reference (NIH)EXOSC9
Genomic and cartography
GoldenPath hg38 (UCSC)EXOSC9  -     chr4:121801317-121817021 +  4q27   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)EXOSC9  -     4q27   [Description]    (hg19-Feb_2009)
EnsemblEXOSC9 - 4q27 [CytoView hg19]  EXOSC9 - 4q27 [CytoView hg38]
Mapping of homologs : NCBIEXOSC9 [Mapview hg19]  EXOSC9 [Mapview hg38]
OMIM606180   
Gene and transcription
Genbank (Entrez)AJ505989 AJ517294 AK301967 AK307548 AK310894
RefSeq transcript (Entrez)NM_001034194 NM_005033
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)EXOSC9
Cluster EST : UnigeneHs.91728 [ NCBI ]
CGAP (NCI)Hs.91728
Alternative Splicing GalleryENSG00000123737
Gene ExpressionEXOSC9 [ NCBI-GEO ]   EXOSC9 [ EBI - ARRAY_EXPRESS ]   EXOSC9 [ SEEK ]   EXOSC9 [ MEM ]
Gene Expression Viewer (FireBrowse)EXOSC9 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)5393
GTEX Portal (Tissue expression)EXOSC9
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ06265   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ06265  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ06265
Splice isoforms : SwissVarQ06265
PhosPhoSitePlusQ06265
Domains : Interpro (EBI)ExoRNase_PH_dom1    ExoRNase_PH_dom2    Ribosomal_S5_D2-typ_fold    Rrp45   
Domain families : Pfam (Sanger)RNase_PH (PF01138)    RNase_PH_C (PF03725)   
Domain families : Pfam (NCBI)pfam01138    pfam03725   
Conserved Domain (NCBI)EXOSC9
DMDM Disease mutations5393
Blocks (Seattle)EXOSC9
PDB (SRS)2NN6   
PDB (PDBSum)2NN6   
PDB (IMB)2NN6   
PDB (RSDB)2NN6   
Structural Biology KnowledgeBase2NN6   
SCOP (Structural Classification of Proteins)2NN6   
CATH (Classification of proteins structures)2NN6   
SuperfamilyQ06265
Human Protein AtlasENSG00000123737
Peptide AtlasQ06265
HPRD07315
IPIIPI00654592   IPI00029697   IPI00845426   IPI00967924   IPI00607722   IPI00966262   IPI00968203   IPI00967775   
Protein Interaction databases
DIP (DOE-UCLA)Q06265
IntAct (EBI)Q06265
FunCoupENSG00000123737
BioGRIDEXOSC9
STRING (EMBL)EXOSC9
ZODIACEXOSC9
Ontologies - Pathways
QuickGOQ06265
Ontology : AmiGO3'-5'-exoribonuclease activity  nuclear exosome (RNase complex)  nuclear exosome (RNase complex)  exosome (RNase complex)  nuclear chromosome  nuclear-transcribed mRNA catabolic process  RNA polymerase II activating transcription factor binding  RNA binding  RNA binding  exoribonuclease activity  protein binding  nucleus  nucleoplasm  nucleoplasm  nucleolus  cytoplasm  cytosol  rRNA processing  rRNA processing  immune response  AU-rich element binding  positive regulation of cell growth  regulation of mRNA stability  exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay  exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay  positive regulation of transcription from RNA polymerase II promoter  extracellular exosome  nuclear mRNA surveillance  nuclear polyadenylation-dependent rRNA catabolic process  RNA phosphodiester bond hydrolysis, exonucleolytic  
Ontology : EGO-EBI3'-5'-exoribonuclease activity  nuclear exosome (RNase complex)  nuclear exosome (RNase complex)  exosome (RNase complex)  nuclear chromosome  nuclear-transcribed mRNA catabolic process  RNA polymerase II activating transcription factor binding  RNA binding  RNA binding  exoribonuclease activity  protein binding  nucleus  nucleoplasm  nucleoplasm  nucleolus  cytoplasm  cytosol  rRNA processing  rRNA processing  immune response  AU-rich element binding  positive regulation of cell growth  regulation of mRNA stability  exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay  exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay  positive regulation of transcription from RNA polymerase II promoter  extracellular exosome  nuclear mRNA surveillance  nuclear polyadenylation-dependent rRNA catabolic process  RNA phosphodiester bond hydrolysis, exonucleolytic  
Pathways : KEGGRNA degradation   
NDEx NetworkEXOSC9
Atlas of Cancer Signalling NetworkEXOSC9
Wikipedia pathwaysEXOSC9
Orthology - Evolution
OrthoDB5393
GeneTree (enSembl)ENSG00000123737
Phylogenetic Trees/Animal Genes : TreeFamEXOSC9
HOVERGENQ06265
HOGENOMQ06265
Homologs : HomoloGeneEXOSC9
Homology/Alignments : Family Browser (UCSC)EXOSC9
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerEXOSC9 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)EXOSC9
dbVarEXOSC9
ClinVarEXOSC9
1000_GenomesEXOSC9 
Exome Variant ServerEXOSC9
ExAC (Exome Aggregation Consortium)EXOSC9 (select the gene name)
Genetic variants : HAPMAP5393
Genomic Variants (DGV)EXOSC9 [DGVbeta]
DECIPHEREXOSC9 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisEXOSC9 
Mutations
ICGC Data PortalEXOSC9 
TCGA Data PortalEXOSC9 
Broad Tumor PortalEXOSC9
OASIS PortalEXOSC9 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICEXOSC9  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDEXOSC9
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch EXOSC9
DgiDB (Drug Gene Interaction Database)EXOSC9
DoCM (Curated mutations)EXOSC9 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)EXOSC9 (select a term)
intoGenEXOSC9
Cancer3DEXOSC9(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM606180   
Orphanet
MedgenEXOSC9
Genetic Testing Registry EXOSC9
NextProtQ06265 [Medical]
TSGene5393
GENETestsEXOSC9
Target ValidationEXOSC9
Huge Navigator EXOSC9 [HugePedia]
snp3D : Map Gene to Disease5393
BioCentury BCIQEXOSC9
ClinGenEXOSC9
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD5393
Chemical/Pharm GKB GenePA33463
Clinical trialEXOSC9
Miscellaneous
canSAR (ICR)EXOSC9 (select the gene name)
Probes
Litterature
PubMed41 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineEXOSC9
EVEXEXOSC9
GoPubMedEXOSC9
iHOPEXOSC9
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Jun 7 15:47:35 CEST 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.