| EXT-mutation analysis and loss of heterozygosity in sporadic and hereditary osteochondromas and secondary chondrosarcomas. |
| Bovée JV, Cleton-Jansen AM, Wuyts W, Caethoven G, Taminiau AH, Bakker E, Van Hul W, Cornelisse CJ, Hogendoorn PC |
| American journal of human genetics. 1999 ; 65 (3) : 689-698. |
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| Clonal karyotypic abnormalities of the hereditary multiple exostoses chromosomal loci 8q24.1 (EXT1) and 11p11-12 (EXT2) in patients with sporadic and hereditary osteochondromas. |
| Bridge JA, Nelson M, Orndal C, Bhatia P, Neff JR |
| Cancer. 1998 ; 82 (9) : 1657-1663. |
| PMID 9576285 |
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| The structure of the human multiple exostoses 2 gene and characterization of homologs in mouse and Caenorhabditis elegans. |
| Clines GA, Ashley JA, Shah S, Lovett M |
| Genome research. 1997 ; 7 (4) : 359-367. |
| PMID 9110175 |
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| Genetic heterogeneity in families with hereditary multiple exostoses. |
| Cook A, Raskind W, Blanton SH, Pauli RM, Gregg RG, Francomano CA, Puffenberger E, Conrad EU, Schmale G, Schellenberg G |
| American journal of human genetics. 1993 ; 53 (1) : 71-79. |
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| Hereditary multiple exostosis and chondrosarcoma: linkage to chromosome II and loss of heterozygosity for EXT-linked markers on chromosomes II and 8. |
| Hecht JT, Hogue D, Strong LC, Hansen MF, Blanton SH, Wagner M |
| American journal of human genetics. 1995 ; 56 (5) : 1125-1131. |
| PMID 7726168 |
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| The tumor suppressor EXT-like gene EXTL2 encodes an alpha1, 4-N-acetylhexosaminyltransferase that transfers N-acetylgalactosamine and N-acetylglucosamine to the common glycosaminoglycan-protein linkage region. The key enzyme for the chain initiation of heparan sulfate. |
| Kitagawa H, Shimakawa H, Sugahara K |
| The Journal of biological chemistry. 1999 ; 274 (20) : 13933-13937. |
| PMID 10318803 |
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| The putative tumor suppressors EXT1 and EXT2 are glycosyltransferases required for the biosynthesis of heparan sulfate. |
| Lind T, Tufaro F, McCormick C, Lindahl U, Lidholt K |
| The Journal of biological chemistry. 1998 ; 273 (41) : 26265-26268. |
| PMID 9756849 |
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| New perspectives on the molecular basis of hereditary bone tumours. |
| McCormick C, Duncan G, Tufaro F |
| Molecular medicine today. 1999 ; 5 (11) : 481-486. |
| PMID 10529789 |
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| Loss of heterozygosity in chondrosarcomas for markers linked to hereditary multiple exostoses loci on chromosomes 8 and 11. |
| Raskind WH, Conrad EU, Chansky H, Matsushita M |
| American journal of human genetics. 1995 ; 56 (5) : 1132-1139. |
| PMID 7726169 |
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| A direct interaction between EXT proteins and glycosyltransferases is defective in hereditary multiple exostoses. |
| Simmons AD, Musy MM, Lopes CS, Hwang LY, Yang YP, Lovett M |
| Human molecular genetics. 1999 ; 8 (12) : 2155-2164. |
| PMID 10545594 |
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| EXT genes are differentially expressed in bone and cartilage during mouse embryogenesis. |
| Stickens D, Brown D, Evans GA |
| Developmental dynamics : an official publication of the American Association of Anatomists. 2000 ; 218 (3) : 452-464. |
| PMID 10878610 |
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| Assignment of a second locus for multiple exostoses to the pericentromeric region of chromosome 11. |
| Wu YQ, Heutink P, de Vries BB, Sandkuijl LA, van den Ouweland AM, Niermeijer MF, Galjaard H, Reyniers E, Willems PJ, Halley DJ |
| Human molecular genetics. 1994 ; 3 (1) : 167-171. |
| PMID 8162019 |
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| Refinement of the multiple exostoses locus (EXT2) to a 3-cM interval on chromosome 11. |
| Wuyts W, Ramlakhan S, Van Hul W, Hecht JT, van den Ouweland AM, Raskind WH, Hofstede FC, Reyniers E, Wells DE, de Vries B |
| American journal of human genetics. 1995 ; 57 (2) : 382-387. |
| PMID 7668264 |
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| Molecular basis of multiple exostoses: mutations in the EXT1 and EXT2 genes. |
| Wuyts W, Van Hul W |
| Human mutation. 2000 ; 15 (3) : 220-227. |
| PMID 10679937 |
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