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F11R (F11 receptor)

Identity

Alias_namesJAM1
junctional adhesion molecule 1
Alias_symbol (synonym)PAM-1
JCAM
JAM-1
JAM-A
JAMA
CD321
Other aliasJAM
KAT
HGNC (Hugo) F11R
LocusID (NCBI) 50848
Atlas_Id 43683
Location 1q23.3  [Link to chromosome band 1q23]
Location_base_pair Starts at 160995206 and ends at 161021343 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
F11R (1q23.3) / F11R (1q23.3)F11R (1q23.3) / GOLGB1 (3q13.33)F11R (1q23.3) / NOS1AP (1q23.3)
PRG2 (11q12.1) / F11R (1q23.3)U2AF2 (19q13.42) / F11R (1q23.3)F11R 1q23.3 / NOS1AP 1q23.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)F11R   14685
Cards
Entrez_Gene (NCBI)F11R  50848  F11 receptor
AliasesCD321; JAM; JAM1; JAMA; 
JCAM; KAT; PAM-1
GeneCards (Weizmann)F11R
Ensembl hg19 (Hinxton)ENSG00000158769 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000158769 [Gene_View]  chr1:160995206-161021343 [Contig_View]  F11R [Vega]
ICGC DataPortalENSG00000158769
TCGA cBioPortalF11R
AceView (NCBI)F11R
Genatlas (Paris)F11R
WikiGenes50848
SOURCE (Princeton)F11R
Genetics Home Reference (NIH)F11R
Genomic and cartography
GoldenPath hg38 (UCSC)F11R  -     chr1:160995206-161021343 -  1q23.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)F11R  -     1q23.3   [Description]    (hg19-Feb_2009)
EnsemblF11R - 1q23.3 [CytoView hg19]  F11R - 1q23.3 [CytoView hg38]
Mapping of homologs : NCBIF11R [Mapview hg19]  F11R [Mapview hg38]
OMIM605721   
Gene and transcription
Genbank (Entrez)AF154005 AF172398 AF207907 AK026665 AK075152
RefSeq transcript (Entrez)NM_001348091 NM_016946 NM_144501 NM_144502 NM_144503 NM_144504
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)F11R
Cluster EST : UnigeneHs.517293 [ NCBI ]
CGAP (NCI)Hs.517293
Alternative Splicing GalleryENSG00000158769
Gene ExpressionF11R [ NCBI-GEO ]   F11R [ EBI - ARRAY_EXPRESS ]   F11R [ SEEK ]   F11R [ MEM ]
Gene Expression Viewer (FireBrowse)F11R [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)50848
GTEX Portal (Tissue expression)F11R
Human Protein AtlasENSG00000158769-F11R [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y624   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y624  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y624
Splice isoforms : SwissVarQ9Y624
PhosPhoSitePlusQ9Y624
Domaine pattern : Prosite (Expaxy)IG_LIKE (PS50835)   
Domains : Interpro (EBI)Ig-like_dom    Ig-like_fold    Ig_sub    Ig_sub2    Ig_V-set    Immunoglobulin   
Domain families : Pfam (Sanger)ig (PF00047)   
Domain families : Pfam (NCBI)pfam00047   
Domain families : Smart (EMBL)IG (SM00409)  IGc2 (SM00408)  IGv (SM00406)  
Conserved Domain (NCBI)F11R
DMDM Disease mutations50848
Blocks (Seattle)F11R
PDB (SRS)1NBQ    3EOY    3TSZ    4ODB   
PDB (PDBSum)1NBQ    3EOY    3TSZ    4ODB   
PDB (IMB)1NBQ    3EOY    3TSZ    4ODB   
PDB (RSDB)1NBQ    3EOY    3TSZ    4ODB   
Structural Biology KnowledgeBase1NBQ    3EOY    3TSZ    4ODB   
SCOP (Structural Classification of Proteins)1NBQ    3EOY    3TSZ    4ODB   
CATH (Classification of proteins structures)1NBQ    3EOY    3TSZ    4ODB   
SuperfamilyQ9Y624
Human Protein Atlas [tissue]ENSG00000158769-F11R [tissue]
Peptide AtlasQ9Y624
HPRD12038
IPIIPI00001754   IPI00922511   IPI00922549   IPI00069985   
Protein Interaction databases
DIP (DOE-UCLA)Q9Y624
IntAct (EBI)Q9Y624
FunCoupENSG00000158769
BioGRIDF11R
STRING (EMBL)F11R
ZODIACF11R
Ontologies - Pathways
QuickGOQ9Y624
Ontology : AmiGOvirus receptor activity  regulation of cytokine production  protein binding  plasma membrane  plasma membrane  cell-cell junction  bicellular tight junction  inflammatory response  cell adhesion  transforming growth factor beta receptor signaling pathway  response to radiation  integral component of membrane  cell junction  PDZ domain binding  extracellular matrix organization  actomyosin structure organization  cytoplasmic vesicle  negative regulation of GTPase activity  slit diaphragm  positive regulation of GTPase activity  cadherin binding  positive regulation of blood pressure  viral entry into host cell  intestinal absorption  leukocyte migration  extracellular exosome  bicellular tight junction assembly  establishment of protein localization to plasma membrane  establishment of endothelial intestinal barrier  establishment of endothelial intestinal barrier  regulation of membrane permeability  regulation of actin cytoskeleton reorganization  
Ontology : EGO-EBIvirus receptor activity  regulation of cytokine production  protein binding  plasma membrane  plasma membrane  cell-cell junction  bicellular tight junction  inflammatory response  cell adhesion  transforming growth factor beta receptor signaling pathway  response to radiation  integral component of membrane  cell junction  PDZ domain binding  extracellular matrix organization  actomyosin structure organization  cytoplasmic vesicle  negative regulation of GTPase activity  slit diaphragm  positive regulation of GTPase activity  cadherin binding  positive regulation of blood pressure  viral entry into host cell  intestinal absorption  leukocyte migration  extracellular exosome  bicellular tight junction assembly  establishment of protein localization to plasma membrane  establishment of endothelial intestinal barrier  establishment of endothelial intestinal barrier  regulation of membrane permeability  regulation of actin cytoskeleton reorganization  
Pathways : KEGGCell adhesion molecules (CAMs)    Tight junction    Leukocyte transendothelial migration    Epithelial cell signaling in Helicobacter pylori infection   
NDEx NetworkF11R
Atlas of Cancer Signalling NetworkF11R
Wikipedia pathwaysF11R
Orthology - Evolution
OrthoDB50848
GeneTree (enSembl)ENSG00000158769
Phylogenetic Trees/Animal Genes : TreeFamF11R
HOVERGENQ9Y624
HOGENOMQ9Y624
Homologs : HomoloGeneF11R
Homology/Alignments : Family Browser (UCSC)F11R
Gene fusions - Rearrangements
Fusion : MitelmanF11R/NOS1AP [1q23.3/1q23.3]  
Fusion: TCGA_MDACCF11R 1q23.3 NOS1AP 1q23.3 LUAD
Tumor Fusion PortalF11R
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerF11R [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)F11R
dbVarF11R
ClinVarF11R
1000_GenomesF11R 
Exome Variant ServerF11R
ExAC (Exome Aggregation Consortium)ENSG00000158769
GNOMAD BrowserENSG00000158769
Genetic variants : HAPMAP50848
Genomic Variants (DGV)F11R [DGVbeta]
DECIPHERF11R [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisF11R 
Mutations
ICGC Data PortalF11R 
TCGA Data PortalF11R 
Broad Tumor PortalF11R
OASIS PortalF11R [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICF11R  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDF11R
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch F11R
DgiDB (Drug Gene Interaction Database)F11R
DoCM (Curated mutations)F11R (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)F11R (select a term)
intoGenF11R
Cancer3DF11R(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605721   
Orphanet
DisGeNETF11R
MedgenF11R
Genetic Testing Registry F11R
NextProtQ9Y624 [Medical]
TSGene50848
GENETestsF11R
Target ValidationF11R
Huge Navigator F11R [HugePedia]
snp3D : Map Gene to Disease50848
BioCentury BCIQF11R
ClinGenF11R
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD50848
Chemical/Pharm GKB GenePA29991
Clinical trialF11R
Miscellaneous
canSAR (ICR)F11R (select the gene name)
Probes
Litterature
PubMed120 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineF11R
EVEXF11R
GoPubMedF11R
iHOPF11R
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 14:12:31 CET 2017

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