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F2RL2 (coagulation factor II thrombin receptor like 2)

Identity

Alias_namescoagulation factor II (thrombin) receptor-like 2
Alias_symbol (synonym)PAR3
Other aliasPAR-3
HGNC (Hugo) F2RL2
LocusID (NCBI) 2151
Atlas_Id 51702
Location 5q13.3  [Link to chromosome band 5q13]
Location_base_pair Starts at 75911307 and ends at 75919238 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)F2RL2   3539
Cards
Entrez_Gene (NCBI)F2RL2  2151  coagulation factor II thrombin receptor like 2
AliasesPAR-3; PAR3
GeneCards (Weizmann)F2RL2
Ensembl hg19 (Hinxton)ENSG00000164220 [Gene_View]  chr5:75911307-75919238 [Contig_View]  F2RL2 [Vega]
Ensembl hg38 (Hinxton)ENSG00000164220 [Gene_View]  chr5:75911307-75919238 [Contig_View]  F2RL2 [Vega]
ICGC DataPortalENSG00000164220
TCGA cBioPortalF2RL2
AceView (NCBI)F2RL2
Genatlas (Paris)F2RL2
WikiGenes2151
SOURCE (Princeton)F2RL2
Genetics Home Reference (NIH)F2RL2
Genomic and cartography
GoldenPath hg19 (UCSC)F2RL2  -     chr5:75911307-75919238 -  5q13.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)F2RL2  -     5q13.3   [Description]    (hg38-Dec_2013)
EnsemblF2RL2 - 5q13.3 [CytoView hg19]  F2RL2 - 5q13.3 [CytoView hg38]
Mapping of homologs : NCBIF2RL2 [Mapview hg19]  F2RL2 [Mapview hg38]
OMIM601919   
Gene and transcription
Genbank (Entrez)AK298585 AK312848 AL048674 BC093648 BC093650
RefSeq transcript (Entrez)NM_001256566 NM_004101
RefSeq genomic (Entrez)NC_000005 NC_018916 NT_034772 NW_004929322
Consensus coding sequences : CCDS (NCBI)F2RL2
Cluster EST : UnigeneHs.42502 [ NCBI ]
CGAP (NCI)Hs.42502
Alternative Splicing GalleryENSG00000164220
Gene ExpressionF2RL2 [ NCBI-GEO ]   F2RL2 [ EBI - ARRAY_EXPRESS ]   F2RL2 [ SEEK ]   F2RL2 [ MEM ]
Gene Expression Viewer (FireBrowse)F2RL2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2151
GTEX Portal (Tissue expression)F2RL2
Protein : pattern, domain, 3D structure
UniProt/SwissProtO00254   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO00254  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO00254
Splice isoforms : SwissVarO00254
PhosPhoSitePlusO00254
Domaine pattern : Prosite (Expaxy)G_PROTEIN_RECEP_F1_1 (PS00237)    G_PROTEIN_RECEP_F1_2 (PS50262)   
Domains : Interpro (EBI)GPCR_Rhodpsn    GPCR_Rhodpsn_7TM    Prot_act_rcpt_3    Protea_act_rcpt   
Domain families : Pfam (Sanger)7tm_1 (PF00001)   
Domain families : Pfam (NCBI)pfam00001   
Conserved Domain (NCBI)F2RL2
DMDM Disease mutations2151
Blocks (Seattle)F2RL2
SuperfamilyO00254
Human Protein AtlasENSG00000164220
Peptide AtlasO00254
HPRD03561
IPIIPI00010870   IPI00967588   
Protein Interaction databases
DIP (DOE-UCLA)O00254
IntAct (EBI)O00254
FunCoupENSG00000164220
BioGRIDF2RL2
STRING (EMBL)F2RL2
ZODIACF2RL2
Ontologies - Pathways
QuickGOO00254
Ontology : AmiGOphosphatidylinositol phospholipase C activity  G-protein coupled receptor activity  protein binding  extracellular region  plasma membrane  integral component of plasma membrane  blood coagulation  response to wounding  thrombin receptor activity  apical plasma membrane  platelet activation  thrombin receptor signaling pathway  
Ontology : EGO-EBIphosphatidylinositol phospholipase C activity  G-protein coupled receptor activity  protein binding  extracellular region  plasma membrane  integral component of plasma membrane  blood coagulation  response to wounding  thrombin receptor activity  apical plasma membrane  platelet activation  thrombin receptor signaling pathway  
Pathways : KEGGNeuroactive ligand-receptor interaction   
NDEx NetworkF2RL2
Atlas of Cancer Signalling NetworkF2RL2
Wikipedia pathwaysF2RL2
Orthology - Evolution
OrthoDB2151
GeneTree (enSembl)ENSG00000164220
Phylogenetic Trees/Animal Genes : TreeFamF2RL2
HOVERGENO00254
HOGENOMO00254
Homologs : HomoloGeneF2RL2
Homology/Alignments : Family Browser (UCSC)F2RL2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerF2RL2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)F2RL2
dbVarF2RL2
ClinVarF2RL2
1000_GenomesF2RL2 
Exome Variant ServerF2RL2
ExAC (Exome Aggregation Consortium)F2RL2 (select the gene name)
Genetic variants : HAPMAP2151
Genomic Variants (DGV)F2RL2 [DGVbeta]
DECIPHER (Syndromes)5:75911307-75919238  ENSG00000164220
CONAN: Copy Number AnalysisF2RL2 
Mutations
ICGC Data PortalF2RL2 
TCGA Data PortalF2RL2 
Broad Tumor PortalF2RL2
OASIS PortalF2RL2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICF2RL2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDF2RL2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch F2RL2
DgiDB (Drug Gene Interaction Database)F2RL2
DoCM (Curated mutations)F2RL2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)F2RL2 (select a term)
intoGenF2RL2
Cancer3DF2RL2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM601919   
Orphanet
MedgenF2RL2
Genetic Testing Registry F2RL2
NextProtO00254 [Medical]
TSGene2151
GENETestsF2RL2
Huge Navigator F2RL2 [HugePedia]
snp3D : Map Gene to Disease2151
BioCentury BCIQF2RL2
ClinGenF2RL2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD2151
Chemical/Pharm GKB GenePA27948
Clinical trialF2RL2
Miscellaneous
canSAR (ICR)F2RL2 (select the gene name)
Probes
Litterature
PubMed61 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineF2RL2
EVEXF2RL2
GoPubMedF2RL2
iHOPF2RL2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 30 15:00:34 CEST 2017

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