Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

F7 (coagulation factor VII)

Identity

Alias_namescoagulation factor VII (serum prothrombin conversion accelerator)
Other aliasSPCA
HGNC (Hugo) F7
LocusID (NCBI) 2155
Atlas_Id 46526
Location 13q34  [Link to chromosome band 13q34]
Location_base_pair Starts at 113105788 and ends at 113120681 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)F7   3544
LRG (Locus Reference Genomic)LRG_554
Cards
Entrez_Gene (NCBI)F7  2155  coagulation factor VII
AliasesSPCA
GeneCards (Weizmann)F7
Ensembl hg19 (Hinxton)ENSG00000057593 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000057593 [Gene_View]  chr13:113105788-113120681 [Contig_View]  F7 [Vega]
ICGC DataPortalENSG00000057593
TCGA cBioPortalF7
AceView (NCBI)F7
Genatlas (Paris)F7
WikiGenes2155
SOURCE (Princeton)F7
Genetics Home Reference (NIH)F7
Genomic and cartography
GoldenPath hg38 (UCSC)F7  -     chr13:113105788-113120681 +  13q34   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)F7  -     13q34   [Description]    (hg19-Feb_2009)
EnsemblF7 - 13q34 [CytoView hg19]  F7 - 13q34 [CytoView hg38]
Mapping of homologs : NCBIF7 [Mapview hg19]  F7 [Mapview hg38]
OMIM227500   608446   613878   
Gene and transcription
Genbank (Entrez)AI076552 AK298404 AK310779 AK311565 AK311682
RefSeq transcript (Entrez)NM_000131 NM_001267554 NM_019616
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)F7
Cluster EST : UnigeneHs.36989 [ NCBI ]
CGAP (NCI)Hs.36989
Alternative Splicing GalleryENSG00000057593
Gene ExpressionF7 [ NCBI-GEO ]   F7 [ EBI - ARRAY_EXPRESS ]   F7 [ SEEK ]   F7 [ MEM ]
Gene Expression Viewer (FireBrowse)F7 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2155
GTEX Portal (Tissue expression)F7
Protein : pattern, domain, 3D structure
UniProt/SwissProtP08709   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP08709  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP08709
Splice isoforms : SwissVarP08709
Catalytic activity : Enzyme3.4.21.21 [ Enzyme-Expasy ]   3.4.21.213.4.21.21 [ IntEnz-EBI ]   3.4.21.21 [ BRENDA ]   3.4.21.21 [ KEGG ]   
PhosPhoSitePlusP08709
Domaine pattern : Prosite (Expaxy)ASX_HYDROXYL (PS00010)    EGF_1 (PS00022)    EGF_2 (PS01186)    EGF_3 (PS50026)    EGF_CA (PS01187)    GLA_1 (PS00011)    GLA_2 (PS50998)    TRYPSIN_DOM (PS50240)    TRYPSIN_HIS (PS00134)    TRYPSIN_SER (PS00135)   
Domains : Interpro (EBI)Coagulation_fac_subgr_Gla_dom    EGF-like_Ca-bd_dom    EGF-like_CS    EGF-like_dom    EGF-type_Asp/Asn_hydroxyl_site    EGF_Ca-bd_CS    F7    GLA_domain    Pept_S1A_FX    Peptidase_S1_PA    Peptidase_S1A    Trypsin_dom    TRYPSIN_HIS    TRYPSIN_SER   
Domain families : Pfam (Sanger)EGF (PF00008)    Gla (PF00594)    Trypsin (PF00089)   
Domain families : Pfam (NCBI)pfam00008    pfam00594    pfam00089   
Domain families : Smart (EMBL)EGF (SM00181)  EGF_CA (SM00179)  GLA (SM00069)  Tryp_SPc (SM00020)  
Conserved Domain (NCBI)F7
DMDM Disease mutations2155
Blocks (Seattle)F7
PDB (SRS)###############################################################################################################################################################################################################################################################   
PDB (PDBSum)###############################################################################################################################################################################################################################################################   
PDB (IMB)###############################################################################################################################################################################################################################################################   
PDB (RSDB)###############################################################################################################################################################################################################################################################   
Structural Biology KnowledgeBase###############################################################################################################################################################################################################################################################   
SCOP (Structural Classification of Proteins)###############################################################################################################################################################################################################################################################   
CATH (Classification of proteins structures)###############################################################################################################################################################################################################################################################   
SuperfamilyP08709
Human Protein AtlasENSG00000057593
Peptide AtlasP08709
HPRD01965
IPIIPI00329555   IPI00798065   IPI00893182   
Protein Interaction databases
DIP (DOE-UCLA)P08709
IntAct (EBI)P08709
FunCoupENSG00000057593
BioGRIDF7
STRING (EMBL)F7
ZODIACF7
Ontologies - Pathways
QuickGOP08709
Ontology : AmiGOresponse to hypoxia  glycoprotein binding  positive regulation of leukocyte chemotaxis  serine-type endopeptidase activity  receptor binding  calcium ion binding  protein binding  extracellular region  extracellular space  endoplasmic reticulum lumen  Golgi lumen  plasma membrane  signal peptide processing  ER to Golgi vesicle-mediated transport  blood coagulation  blood coagulation, extrinsic pathway  circadian rhythm  serine-type peptidase activity  response to carbon dioxide  positive regulation of platelet-derived growth factor receptor signaling pathway  protein processing  peptidyl-glutamic acid carboxylation  positive regulation of blood coagulation  positive regulation of cell migration  animal organ regeneration  vesicle  response to estradiol  response to vitamin K  response to genistein  response to estrogen  positive regulation of positive chemotaxis  positive regulation of protein kinase B signaling  response to growth hormone  response to anticoagulant  response to cholesterol  response to thyroxine  response to Thyroid stimulating hormone  response to 2,3,7,8-tetrachlorodibenzodioxine  response to astaxanthin  response to thyrotropin-releasing hormone  serine-type peptidase complex  
Ontology : EGO-EBIresponse to hypoxia  glycoprotein binding  positive regulation of leukocyte chemotaxis  serine-type endopeptidase activity  receptor binding  calcium ion binding  protein binding  extracellular region  extracellular space  endoplasmic reticulum lumen  Golgi lumen  plasma membrane  signal peptide processing  ER to Golgi vesicle-mediated transport  blood coagulation  blood coagulation, extrinsic pathway  circadian rhythm  serine-type peptidase activity  response to carbon dioxide  positive regulation of platelet-derived growth factor receptor signaling pathway  protein processing  peptidyl-glutamic acid carboxylation  positive regulation of blood coagulation  positive regulation of cell migration  animal organ regeneration  vesicle  response to estradiol  response to vitamin K  response to genistein  response to estrogen  positive regulation of positive chemotaxis  positive regulation of protein kinase B signaling  response to growth hormone  response to anticoagulant  response to cholesterol  response to thyroxine  response to Thyroid stimulating hormone  response to 2,3,7,8-tetrachlorodibenzodioxine  response to astaxanthin  response to thyrotropin-releasing hormone  serine-type peptidase complex  
Pathways : BIOCARTAExtrinsic Prothrombin Activation Pathway [Genes]    Acute Myocardial Infarction [Genes]   
Pathways : KEGGComplement and coagulation cascades   
NDEx NetworkF7
Atlas of Cancer Signalling NetworkF7
Wikipedia pathwaysF7
Orthology - Evolution
OrthoDB2155
GeneTree (enSembl)ENSG00000057593
Phylogenetic Trees/Animal Genes : TreeFamF7
HOVERGENP08709
HOGENOMP08709
Homologs : HomoloGeneF7
Homology/Alignments : Family Browser (UCSC)F7
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerF7 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)F7
dbVarF7
ClinVarF7
1000_GenomesF7 
Exome Variant ServerF7
ExAC (Exome Aggregation Consortium)F7 (select the gene name)
Genetic variants : HAPMAP2155
Genomic Variants (DGV)F7 [DGVbeta]
DECIPHERF7 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisF7 
Mutations
ICGC Data PortalF7 
TCGA Data PortalF7 
Broad Tumor PortalF7
OASIS PortalF7 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICF7  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDF7
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)Mendelian genes
BioMutasearch F7
DgiDB (Drug Gene Interaction Database)F7
DoCM (Curated mutations)F7 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)F7 (select a term)
intoGenF7
Cancer3DF7(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM227500    608446    613878   
Orphanet916   
MedgenF7
Genetic Testing Registry F7
NextProtP08709 [Medical]
TSGene2155
GENETestsF7
Huge Navigator F7 [HugePedia]
snp3D : Map Gene to Disease2155
BioCentury BCIQF7
ClinGenF7
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD2155
Chemical/Pharm GKB GenePA160
Clinical trialF7
Miscellaneous
canSAR (ICR)F7 (select the gene name)
Probes
Litterature
PubMed429 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineF7
EVEXF7
GoPubMedF7
iHOPF7
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri May 19 12:15:13 CEST 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.