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F9 (coagulation factor IX)

Identity

Alias_symbol (synonym)FIX
Other aliasF9 p22
HEMB
P19
PTC
THPH8
HGNC (Hugo) F9
LocusID (NCBI) 2158
Atlas_Id 56350
Location Xq27.1  [Link to chromosome band Xq27]
Location_base_pair Starts at 139530736 and ends at 139563458 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)F9   3551
LRG (Locus Reference Genomic)LRG_556
Cards
Entrez_Gene (NCBI)F9  2158  coagulation factor IX
AliasesF9; FIX; HEMB; P19; 
PTC; THPH8
GeneCards (Weizmann)F9
Ensembl hg19 (Hinxton)ENSG00000101981 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000101981 [Gene_View]  chrX:139530736-139563458 [Contig_View]  F9 [Vega]
ICGC DataPortalENSG00000101981
TCGA cBioPortalF9
AceView (NCBI)F9
Genatlas (Paris)F9
WikiGenes2158
SOURCE (Princeton)F9
Genetics Home Reference (NIH)F9
Genomic and cartography
GoldenPath hg38 (UCSC)F9  -     chrX:139530736-139563458 +  Xq27.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)F9  -     Xq27.1   [Description]    (hg19-Feb_2009)
EnsemblF9 - Xq27.1 [CytoView hg19]  F9 - Xq27.1 [CytoView hg38]
Mapping of homologs : NCBIF9 [Mapview hg19]  F9 [Mapview hg38]
OMIM122700   300746   300807   306900   
Gene and transcription
Genbank (Entrez)A13997 AB186358 AK292749 BC109214 BC109215
RefSeq transcript (Entrez)NM_000133 NM_001313913
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)F9
Cluster EST : UnigeneHs.522798 [ NCBI ]
CGAP (NCI)Hs.522798
Alternative Splicing GalleryENSG00000101981
Gene ExpressionF9 [ NCBI-GEO ]   F9 [ EBI - ARRAY_EXPRESS ]   F9 [ SEEK ]   F9 [ MEM ]
Gene Expression Viewer (FireBrowse)F9 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2158
GTEX Portal (Tissue expression)F9
Protein : pattern, domain, 3D structure
UniProt/SwissProtP00740   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP00740  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP00740
Splice isoforms : SwissVarP00740
PhosPhoSitePlusP00740
Domaine pattern : Prosite (Expaxy)ASX_HYDROXYL (PS00010)    EGF_1 (PS00022)    EGF_2 (PS01186)    EGF_3 (PS50026)    EGF_CA (PS01187)    GLA_1 (PS00011)    GLA_2 (PS50998)    TRYPSIN_DOM (PS50240)    TRYPSIN_HIS (PS00134)    TRYPSIN_SER (PS00135)   
Domains : Interpro (EBI)Coagulation_fac_subgr_Gla_dom    EGF-like_Ca-bd_dom    EGF-like_CS    EGF-like_dom    EGF-type_Asp/Asn_hydroxyl_site    EGF_Ca-bd_CS    GLA_domain    Pept_S1A_FX    Peptidase_S1_PA    Peptidase_S1A    Trypsin_dom    TRYPSIN_HIS    TRYPSIN_SER   
Domain families : Pfam (Sanger)EGF (PF00008)    Gla (PF00594)    Trypsin (PF00089)   
Domain families : Pfam (NCBI)pfam00008    pfam00594    pfam00089   
Domain families : Smart (EMBL)EGF (SM00181)  EGF_CA (SM00179)  GLA (SM00069)  Tryp_SPc (SM00020)  
Conserved Domain (NCBI)F9
DMDM Disease mutations2158
Blocks (Seattle)F9
PDB (SRS)1CFH    1CFI    1EDM    1IXA    1MGX    1NL0    1RFN    2WPH    2WPI    2WPJ    2WPK    2WPL    2WPM    3KCG    3LC3    3LC5    4WM0    4WMA    4WMB    4WMI    4WMK    4WN2    4WNH    4YZU    4Z0K    4ZAE    5EGM    5F84    5F85    5F86    5JB8    5JB9    5JBA    5JBB    5JBC   
PDB (PDBSum)1CFH    1CFI    1EDM    1IXA    1MGX    1NL0    1RFN    2WPH    2WPI    2WPJ    2WPK    2WPL    2WPM    3KCG    3LC3    3LC5    4WM0    4WMA    4WMB    4WMI    4WMK    4WN2    4WNH    4YZU    4Z0K    4ZAE    5EGM    5F84    5F85    5F86    5JB8    5JB9    5JBA    5JBB    5JBC   
PDB (IMB)1CFH    1CFI    1EDM    1IXA    1MGX    1NL0    1RFN    2WPH    2WPI    2WPJ    2WPK    2WPL    2WPM    3KCG    3LC3    3LC5    4WM0    4WMA    4WMB    4WMI    4WMK    4WN2    4WNH    4YZU    4Z0K    4ZAE    5EGM    5F84    5F85    5F86    5JB8    5JB9    5JBA    5JBB    5JBC   
PDB (RSDB)1CFH    1CFI    1EDM    1IXA    1MGX    1NL0    1RFN    2WPH    2WPI    2WPJ    2WPK    2WPL    2WPM    3KCG    3LC3    3LC5    4WM0    4WMA    4WMB    4WMI    4WMK    4WN2    4WNH    4YZU    4Z0K    4ZAE    5EGM    5F84    5F85    5F86    5JB8    5JB9    5JBA    5JBB    5JBC   
Structural Biology KnowledgeBase1CFH    1CFI    1EDM    1IXA    1MGX    1NL0    1RFN    2WPH    2WPI    2WPJ    2WPK    2WPL    2WPM    3KCG    3LC3    3LC5    4WM0    4WMA    4WMB    4WMI    4WMK    4WN2    4WNH    4YZU    4Z0K    4ZAE    5EGM    5F84    5F85    5F86    5JB8    5JB9    5JBA    5JBB    5JBC   
SCOP (Structural Classification of Proteins)1CFH    1CFI    1EDM    1IXA    1MGX    1NL0    1RFN    2WPH    2WPI    2WPJ    2WPK    2WPL    2WPM    3KCG    3LC3    3LC5    4WM0    4WMA    4WMB    4WMI    4WMK    4WN2    4WNH    4YZU    4Z0K    4ZAE    5EGM    5F84    5F85    5F86    5JB8    5JB9    5JBA    5JBB    5JBC   
CATH (Classification of proteins structures)1CFH    1CFI    1EDM    1IXA    1MGX    1NL0    1RFN    2WPH    2WPI    2WPJ    2WPK    2WPL    2WPM    3KCG    3LC3    3LC5    4WM0    4WMA    4WMB    4WMI    4WMK    4WN2    4WNH    4YZU    4Z0K    4ZAE    5EGM    5F84    5F85    5F86    5JB8    5JB9    5JBA    5JBB    5JBC   
SuperfamilyP00740
Human Protein AtlasENSG00000101981
Peptide AtlasP00740
HPRD02385
IPIIPI00296176   IPI00816532   IPI00930648   IPI01012693   
Protein Interaction databases
DIP (DOE-UCLA)P00740
IntAct (EBI)P00740
FunCoupENSG00000101981
BioGRIDF9
STRING (EMBL)F9
ZODIACF9
Ontologies - Pathways
QuickGOP00740
Ontology : AmiGOendopeptidase activity  serine-type endopeptidase activity  calcium ion binding  extracellular region  extracellular region  extracellular space  endoplasmic reticulum lumen  Golgi lumen  plasma membrane  signal peptide processing  proteolysis  ER to Golgi vesicle-mediated transport  blood coagulation  blood coagulation  blood coagulation, intrinsic pathway  blood coagulation, extrinsic pathway  peptidyl-glutamic acid carboxylation  zymogen activation  extracellular exosome  
Ontology : EGO-EBIendopeptidase activity  serine-type endopeptidase activity  calcium ion binding  extracellular region  extracellular region  extracellular space  endoplasmic reticulum lumen  Golgi lumen  plasma membrane  signal peptide processing  proteolysis  ER to Golgi vesicle-mediated transport  blood coagulation  blood coagulation  blood coagulation, intrinsic pathway  blood coagulation, extrinsic pathway  peptidyl-glutamic acid carboxylation  zymogen activation  extracellular exosome  
Pathways : BIOCARTAIntrinsic Prothrombin Activation Pathway [Genes]    Platelet Amyloid Precursor Protein Pathway [Genes]   
Pathways : KEGGComplement and coagulation cascades   
NDEx NetworkF9
Atlas of Cancer Signalling NetworkF9
Wikipedia pathwaysF9
Orthology - Evolution
OrthoDB2158
GeneTree (enSembl)ENSG00000101981
Phylogenetic Trees/Animal Genes : TreeFamF9
HOVERGENP00740
HOGENOMP00740
Homologs : HomoloGeneF9
Homology/Alignments : Family Browser (UCSC)F9
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerF9 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)F9
dbVarF9
ClinVarF9
1000_GenomesF9 
Exome Variant ServerF9
ExAC (Exome Aggregation Consortium)F9 (select the gene name)
Genetic variants : HAPMAP2158
Genomic Variants (DGV)F9 [DGVbeta]
DECIPHERF9 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisF9 
Mutations
ICGC Data PortalF9 
TCGA Data PortalF9 
Broad Tumor PortalF9
OASIS PortalF9 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICF9  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDF9
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)EAHAD Coagulation Factor Variant Databases
BioMutasearch F9
DgiDB (Drug Gene Interaction Database)F9
DoCM (Curated mutations)F9 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)F9 (select a term)
intoGenF9
Cancer3DF9(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM122700    300746    300807    306900   
Orphanet17871    17870    17869    17997   
MedgenF9
Genetic Testing Registry F9
NextProtP00740 [Medical]
TSGene2158
GENETestsF9
Target ValidationF9
Huge Navigator F9 [HugePedia]
snp3D : Map Gene to Disease2158
BioCentury BCIQF9
ClinGenF9
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD2158
Chemical/Pharm GKB GenePA27954
Clinical trialF9
Miscellaneous
canSAR (ICR)F9 (select the gene name)
Probes
Litterature
PubMed237 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineF9
EVEXF9
GoPubMedF9
iHOPF9
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Sep 25 19:07:34 CEST 2017

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