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FAAH (fatty acid amide hydrolase)

Identity

Alias_symbol (synonym)FAAH-1
Other aliasPSAB
HGNC (Hugo) FAAH
LocusID (NCBI) 2166
Atlas_Id 50330
Location 1p33  [Link to chromosome band 1p33]
Location_base_pair Starts at 46394267 and ends at 46413848 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
FAAH (1p33) / FAAH (1p33)FAAH (1p33) / RAD54L (1p34.1)KIF24 (9p13.3) / FAAH (1p33)
NSUN4 (1p33) / FAAH (1p33)FAAH 1p33 / RAD54L 1p34.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 3 ]
  Lung: Translocations in Squamous Cell Carcinoma
t(1;1)(p33;p34) FAAH/RAD54L
t(1;9)(p33;p13) KIF24/FAAH


External links

Nomenclature
HGNC (Hugo)FAAH   3553
Cards
Entrez_Gene (NCBI)FAAH  2166  fatty acid amide hydrolase
AliasesFAAH-1; PSAB
GeneCards (Weizmann)FAAH
Ensembl hg19 (Hinxton)ENSG00000117480 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000117480 [Gene_View]  ENSG00000117480 [Sequence]  chr1:46394267-46413848 [Contig_View]  FAAH [Vega]
ICGC DataPortalENSG00000117480
TCGA cBioPortalFAAH
AceView (NCBI)FAAH
Genatlas (Paris)FAAH
WikiGenes2166
SOURCE (Princeton)FAAH
Genetics Home Reference (NIH)FAAH
Genomic and cartography
GoldenPath hg38 (UCSC)FAAH  -     chr1:46394267-46413848 +  1p33   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)FAAH  -     1p33   [Description]    (hg19-Feb_2009)
EnsemblFAAH - 1p33 [CytoView hg19]  FAAH - 1p33 [CytoView hg38]
Mapping of homologs : NCBIFAAH [Mapview hg19]  FAAH [Mapview hg38]
OMIM602935   606581   
Gene and transcription
Genbank (Entrez)AL050372 BC034478 BC093632 BC110404 BC111941
RefSeq transcript (Entrez)NM_001441
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)FAAH
Cluster EST : UnigeneHs.720143 [ NCBI ]
CGAP (NCI)Hs.720143
Alternative Splicing GalleryENSG00000117480
Gene ExpressionFAAH [ NCBI-GEO ]   FAAH [ EBI - ARRAY_EXPRESS ]   FAAH [ SEEK ]   FAAH [ MEM ]
Gene Expression Viewer (FireBrowse)FAAH [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2166
GTEX Portal (Tissue expression)FAAH
Human Protein AtlasENSG00000117480-FAAH [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO00519   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO00519  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO00519
Splice isoforms : SwissVarO00519
Catalytic activity : Enzyme3.5.1.99 [ Enzyme-Expasy ]   3.5.1.993.5.1.99 [ IntEnz-EBI ]   3.5.1.99 [ BRENDA ]   3.5.1.99 [ KEGG ]   
PhosPhoSitePlusO00519
Domaine pattern : Prosite (Expaxy)AMIDASES (PS00571)   
Domains : Interpro (EBI)Amidase    Amidase_CS    Amidase_dom    FAAH   
Domain families : Pfam (Sanger)Amidase (PF01425)   
Domain families : Pfam (NCBI)pfam01425   
Conserved Domain (NCBI)FAAH
DMDM Disease mutations2166
Blocks (Seattle)FAAH
SuperfamilyO00519
Human Protein Atlas [tissue]ENSG00000117480-FAAH [tissue]
Peptide AtlasO00519
HPRD04244
IPIIPI00012107   IPI00744157   
Protein Interaction databases
DIP (DOE-UCLA)O00519
IntAct (EBI)O00519
FunCoupENSG00000117480
BioGRIDFAAH
STRING (EMBL)FAAH
ZODIACFAAH
Ontologies - Pathways
QuickGOO00519
Ontology : AmiGOamidase activity  protein binding  endoplasmic reticulum membrane  cytoskeleton  fatty acid catabolic process  integral component of membrane  fatty acid amide hydrolase activity  fatty acid amide hydrolase activity  arachidonic acid metabolic process  organelle membrane  acylglycerol lipase activity  oleamide hydrolase activity  anandamide amidohydrolase activity  
Ontology : EGO-EBIamidase activity  protein binding  endoplasmic reticulum membrane  cytoskeleton  fatty acid catabolic process  integral component of membrane  fatty acid amide hydrolase activity  fatty acid amide hydrolase activity  arachidonic acid metabolic process  organelle membrane  acylglycerol lipase activity  oleamide hydrolase activity  anandamide amidohydrolase activity  
Pathways : BIOCARTAMetabolism of Anandamide, an Endogenous Cannabinoid [Genes]   
NDEx NetworkFAAH
Atlas of Cancer Signalling NetworkFAAH
Wikipedia pathwaysFAAH
Orthology - Evolution
OrthoDB2166
GeneTree (enSembl)ENSG00000117480
Phylogenetic Trees/Animal Genes : TreeFamFAAH
HOVERGENO00519
HOGENOMO00519
Homologs : HomoloGeneFAAH
Homology/Alignments : Family Browser (UCSC)FAAH
Gene fusions - Rearrangements
Fusion : MitelmanFAAH/RAD54L [1p33/1p34.1]  
Fusion : MitelmanKIF24/FAAH [9p13.3/1p33]  [t(1;9)(p33;p13)]  
Fusion PortalFAAH 1p33 RAD54L 1p34.1 LUAD
Fusion : QuiverFAAH
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerFAAH [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)FAAH
dbVarFAAH
ClinVarFAAH
1000_GenomesFAAH 
Exome Variant ServerFAAH
ExAC (Exome Aggregation Consortium)ENSG00000117480
GNOMAD BrowserENSG00000117480
Genetic variants : HAPMAP2166
Genomic Variants (DGV)FAAH [DGVbeta]
DECIPHERFAAH [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisFAAH 
Mutations
ICGC Data PortalFAAH 
TCGA Data PortalFAAH 
Broad Tumor PortalFAAH
OASIS PortalFAAH [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICFAAH  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDFAAH
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch FAAH
DgiDB (Drug Gene Interaction Database)FAAH
DoCM (Curated mutations)FAAH (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)FAAH (select a term)
intoGenFAAH
Cancer3DFAAH(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602935    606581   
Orphanet
DisGeNETFAAH
MedgenFAAH
Genetic Testing Registry FAAH
NextProtO00519 [Medical]
TSGene2166
GENETestsFAAH
Target ValidationFAAH
Huge Navigator FAAH [HugePedia]
snp3D : Map Gene to Disease2166
BioCentury BCIQFAAH
ClinGenFAAH
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD2166
Chemical/Pharm GKB GenePA27955
Clinical trialFAAH
Miscellaneous
canSAR (ICR)FAAH (select the gene name)
Probes
Litterature
PubMed139 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineFAAH
EVEXFAAH
GoPubMedFAAH
iHOPFAAH
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri Jun 22 16:24:54 CEST 2018

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