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FABP1 (fatty acid binding protein 1)

Identity

Alias_namesfatty acid binding protein 1
Alias_symbol (synonym)L-FABP
Other aliasFABPL
HGNC (Hugo) FABP1
LocusID (NCBI) 2168
Atlas_Id 50906
Location 2p11.2  [Link to chromosome band 2p11]
Location_base_pair Starts at 88122989 and ends at 88128131 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
FABP1 (2p11.2) / FABP1 (2p11.2)GOT1 (10q24.2) / FABP1 (2p11.2)PRDM10 (11q24.3) / FABP1 (2p11.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)FABP1   3555
Cards
Entrez_Gene (NCBI)FABP1  2168  fatty acid binding protein 1
AliasesFABPL; L-FABP
GeneCards (Weizmann)FABP1
Ensembl hg19 (Hinxton)ENSG00000163586 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000163586 [Gene_View]  chr2:88122989-88128131 [Contig_View]  FABP1 [Vega]
ICGC DataPortalENSG00000163586
TCGA cBioPortalFABP1
AceView (NCBI)FABP1
Genatlas (Paris)FABP1
WikiGenes2168
SOURCE (Princeton)FABP1
Genetics Home Reference (NIH)FABP1
Genomic and cartography
GoldenPath hg38 (UCSC)FABP1  -     chr2:88122989-88128131 -  2p11.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)FABP1  -     2p11.2   [Description]    (hg19-Feb_2009)
EnsemblFABP1 - 2p11.2 [CytoView hg19]  FABP1 - 2p11.2 [CytoView hg38]
Mapping of homologs : NCBIFABP1 [Mapview hg19]  FABP1 [Mapview hg38]
OMIM134650   
Gene and transcription
Genbank (Entrez)AA345359 BC022287 BC032801 BP263155 BX641099
RefSeq transcript (Entrez)NM_001443
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)FABP1
Cluster EST : UnigeneHs.380135 [ NCBI ]
CGAP (NCI)Hs.380135
Alternative Splicing GalleryENSG00000163586
Gene ExpressionFABP1 [ NCBI-GEO ]   FABP1 [ EBI - ARRAY_EXPRESS ]   FABP1 [ SEEK ]   FABP1 [ MEM ]
Gene Expression Viewer (FireBrowse)FABP1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2168
GTEX Portal (Tissue expression)FABP1
Protein : pattern, domain, 3D structure
UniProt/SwissProtP07148   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP07148  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP07148
Splice isoforms : SwissVarP07148
PhosPhoSitePlusP07148
Domaine pattern : Prosite (Expaxy)FABP (PS00214)   
Domains : Interpro (EBI)Calycin    Calycin-like    Fatty_acid-bd    iLBP    Lb-FABP   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)FABP1
DMDM Disease mutations2168
Blocks (Seattle)FABP1
PDB (SRS)2F73    2L67    2L68    2LKK    2PY1    3B2H    3B2I    3B2J    3B2K    3B2L    3STK    3STM    3STN    3VG2    3VG3    3VG4    3VG5    3VG6    3VG7   
PDB (PDBSum)2F73    2L67    2L68    2LKK    2PY1    3B2H    3B2I    3B2J    3B2K    3B2L    3STK    3STM    3STN    3VG2    3VG3    3VG4    3VG5    3VG6    3VG7   
PDB (IMB)2F73    2L67    2L68    2LKK    2PY1    3B2H    3B2I    3B2J    3B2K    3B2L    3STK    3STM    3STN    3VG2    3VG3    3VG4    3VG5    3VG6    3VG7   
PDB (RSDB)2F73    2L67    2L68    2LKK    2PY1    3B2H    3B2I    3B2J    3B2K    3B2L    3STK    3STM    3STN    3VG2    3VG3    3VG4    3VG5    3VG6    3VG7   
Structural Biology KnowledgeBase2F73    2L67    2L68    2LKK    2PY1    3B2H    3B2I    3B2J    3B2K    3B2L    3STK    3STM    3STN    3VG2    3VG3    3VG4    3VG5    3VG6    3VG7   
SCOP (Structural Classification of Proteins)2F73    2L67    2L68    2LKK    2PY1    3B2H    3B2I    3B2J    3B2K    3B2L    3STK    3STM    3STN    3VG2    3VG3    3VG4    3VG5    3VG6    3VG7   
CATH (Classification of proteins structures)2F73    2L67    2L68    2LKK    2PY1    3B2H    3B2I    3B2J    3B2K    3B2L    3STK    3STM    3STN    3VG2    3VG3    3VG4    3VG5    3VG6    3VG7   
SuperfamilyP07148
Human Protein AtlasENSG00000163586
Peptide AtlasP07148
HPRD00612
IPIIPI00010290   IPI00788848   
Protein Interaction databases
DIP (DOE-UCLA)P07148
IntAct (EBI)P07148
FunCoupENSG00000163586
BioGRIDFABP1
STRING (EMBL)FABP1
ZODIACFABP1
Ontologies - Pathways
QuickGOP07148
Ontology : AmiGOchromatin binding  long-chain fatty acid transporter activity  fatty acid binding  protein binding  phospholipid binding  nucleoplasm  nucleoplasm  peroxisomal matrix  cytosol  cytosol  drug binding  positive regulation of cell proliferation  long-chain fatty acid transport  antioxidant activity  triglyceride catabolic process  positive regulation of fatty acid beta-oxidation  bile acid binding  negative regulation of apoptotic process  negative regulation of cysteine-type endopeptidase activity involved in apoptotic process  protein complex  cellular lipid metabolic process  apical cortex  intestinal absorption  positive regulation of hydrolase activity  extracellular exosome  cellular response to hydrogen peroxide  cellular response to hypoxia  cellular oxidant detoxification  
Ontology : EGO-EBIchromatin binding  long-chain fatty acid transporter activity  fatty acid binding  protein binding  phospholipid binding  nucleoplasm  nucleoplasm  peroxisomal matrix  cytosol  cytosol  drug binding  positive regulation of cell proliferation  long-chain fatty acid transport  antioxidant activity  triglyceride catabolic process  positive regulation of fatty acid beta-oxidation  bile acid binding  negative regulation of apoptotic process  negative regulation of cysteine-type endopeptidase activity involved in apoptotic process  protein complex  cellular lipid metabolic process  apical cortex  intestinal absorption  positive regulation of hydrolase activity  extracellular exosome  cellular response to hydrogen peroxide  cellular response to hypoxia  cellular oxidant detoxification  
Pathways : BIOCARTAMechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha) [Genes]   
Pathways : KEGGPPAR signaling pathway    Fat digestion and absorption   
NDEx NetworkFABP1
Atlas of Cancer Signalling NetworkFABP1
Wikipedia pathwaysFABP1
Orthology - Evolution
OrthoDB2168
GeneTree (enSembl)ENSG00000163586
Phylogenetic Trees/Animal Genes : TreeFamFABP1
HOVERGENP07148
HOGENOMP07148
Homologs : HomoloGeneFABP1
Homology/Alignments : Family Browser (UCSC)FABP1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerFABP1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)FABP1
dbVarFABP1
ClinVarFABP1
1000_GenomesFABP1 
Exome Variant ServerFABP1
ExAC (Exome Aggregation Consortium)FABP1 (select the gene name)
Genetic variants : HAPMAP2168
Genomic Variants (DGV)FABP1 [DGVbeta]
DECIPHERFABP1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisFABP1 
Mutations
ICGC Data PortalFABP1 
TCGA Data PortalFABP1 
Broad Tumor PortalFABP1
OASIS PortalFABP1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICFABP1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDFABP1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch FABP1
DgiDB (Drug Gene Interaction Database)FABP1
DoCM (Curated mutations)FABP1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)FABP1 (select a term)
intoGenFABP1
Cancer3DFABP1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM134650   
Orphanet
MedgenFABP1
Genetic Testing Registry FABP1
NextProtP07148 [Medical]
TSGene2168
GENETestsFABP1
Target ValidationFABP1
Huge Navigator FABP1 [HugePedia]
snp3D : Map Gene to Disease2168
BioCentury BCIQFABP1
ClinGenFABP1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD2168
Chemical/Pharm GKB GenePA27956
Clinical trialFABP1
Miscellaneous
canSAR (ICR)FABP1 (select the gene name)
Probes
Litterature
PubMed115 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineFABP1
EVEXFABP1
GoPubMedFABP1
iHOPFABP1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:52:58 CEST 2017

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