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FABP1 (fatty acid binding protein 1, liver)

Identity

Other namesFABPL
L-FABP
HGNC (Hugo) FABP1
Location 2p11.2
Location_base_pair Starts at 88203625 and ends at 88208693 bp from pter ( according to hg18-March_2006)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)FABP1   3555
Entrez_Gene (NCBI)FABP1  2168  fatty acid binding protein 1, liver
Cards
GeneCards (Weizmann)FABP1
Ensembl (Hinxton)ENSG00000163586 [Gene_View]  FABP1 [Vega]
AceView (NCBI)FABP1
Genatlas (Paris)FABP1
euGene (Indiana)2168
SOURCE (Stanford)NM_001443
Gene Expression (Array Express) ENSG00000163586
Genomic and cartography
GoldenPath (UCSC)FABP1  -  2p11.2   chr2:88203625-88208693 -  2p11.2   [Description]    (hg18-March_2006)
EnsemblFABP1 - 2p11.2 [CytoView]
Mapping of homologs : NCBIFABP1 [Mapview]
OMIM134650   
Gene and transcription
Gene : Genbank (Entrez)BC022287 BC032801 CR542090 CR590669 CR612744
Reference sequence (RefSeq transcript) :SRSNM_001443
Reference transcript : EntrezNM_001443
RefSeq genomic : SRSAC_000045 AC_000134 NC_000002 NT_022184 NW_001838785 NW_927808
RefSeq genomic : EntrezAC_000045 AC_000134 NC_000002 NT_022184 NW_001838785 NW_927808
Consensus coding sequences : CCDS NCBIFABP1
Cluster EST : UnigeneHs.380135 [ SRS ] Hs.380135 [ NCBI ]
Protein : pattern, domain, 3D structure
Protein : UniProt/SwissProtP07148 (SRS) P07148 (Expasy) P07148 (Uniprot)
With graphics : InterProP07148
Splice isoforms : VarSplice FASTAP07148(VarSplice FASTA)
Domaine pattern : Prosite (SRS)FABP (PS00214)   
Domain pattern : Prosite (Expaxy)FABP (PS00214)   
Domains : Interpro (SRS)Calycin    Calycin-like    Fatty_acid_bd    Lipocln_cytFABP   
Domains : Interpro (EBI)Calycin    Calycin-like    Fatty_acid_bd    Lipocln_cytFABP   
Related proteins : CluSTrP07148
Domain families : Pfam SRSLipocalin (PF00061)   
Domain families : Pfam SangerLipocalin (PF00061)   
Domain families : Pfam NCBIpfam00061   
Blocks (Seattle)P07148
Crystal structure of protein : PDB SRS2F73    2PY1   
Crystal structure of protein : PDBSum2F73    2PY1   
Crystal structure of protein : IMB2F73    2PY1   
Crystal structure of protein : PDB RSDB2F73    2PY1   
HPRD00612
Protein Interaction databases
DIP (DOE-UCLA)P07148
IntAct (EBI)P07148
Polymorphism : SNP, mutations, diseases
Single Nucleotide Polymorphism (SNP) : dbSNP NCBIFABP1
SNP : GeneSNP UtahFABP1
SNP : HGBaseFABP1
Genetic variants : HAPMAPFABP1
Somatic Mutations in Cancer : COSMICFABP1 
Mutations and Diseases : HGMDFABP1
Hereditary diseases : OMIM134650   
Hereditary diseases : GENETests134650   
Diseases : Genetic AssociationFABP1
General knowledge
Homologs : HomoloGeneFABP1
Homology/Alignments : Family Browser UCSCFABP1
Phylogenetic Trees/Animal Genes : TreeFamFABP1
Chemical/Protein Interactions : CTD2168
Keywords Ontology : AmiGOchromatin binding  transporter activity  long-chain fatty acid transporter activity  fatty acid binding  phospholipid binding  nucleus  cytoplasm  peroxisomal matrix  cytosol  transport  drug binding  positive regulation of cell proliferation  organ morphogenesis  long-chain fatty acid transport  positive regulation of fatty acid beta-oxidation  bile acid binding  apical cortex  intestinal absorption  positive regulation of hydrolase activity  
Keywords Ontology : EGO-EBIchromatin binding  transporter activity  long-chain fatty acid transporter activity  fatty acid binding  phospholipid binding  nucleus  cytoplasm  peroxisomal matrix  cytosol  transport  drug binding  positive regulation of cell proliferation  organ morphogenesis  long-chain fatty acid transport  positive regulation of fatty acid beta-oxidation  bile acid binding  apical cortex  intestinal absorption  positive regulation of hydrolase activity  
Pathways : BIOCARTAMechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha) [Genes]   
Pathways : KEGGPPAR signaling pathway
Other databases
Probes
Probes : ImagenesFABP1 Related clones (RZPD - Berlin)
Literature
PubMed44 Pubmed reference(s) in Entrez
PubGeneFABP1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated03-2009Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sat Feb 6 13:33:40 CET 2010
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