Atlas of Genetics and Cytogenetics in Oncology and Haematology

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FABP3 (fatty acid binding protein 3)

Identity

Alias_namesMDGI
FABP11
fatty acid binding protein 11
fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor)
fatty acid binding protein 3, muscle and heart
Alias_symbol (synonym)H-FABP
O-FABP
Other aliasM-FABP
HGNC (Hugo) FABP3
LocusID (NCBI) 2170
Atlas_Id 40524
Location 1p35.2  [Link to chromosome band 1p35]
Location_base_pair Starts at 31365253 and ends at 31373288 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
FABP3 (1p35.2) / UBL3 (13q12.3)ZCCHC17 (1p35.2) / FABP3 (1p35.2)ZCCHC17 1p35.2 / FABP3 1p35.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]

Solid Tumors TT_t0101p35p35ID103735

External links

Nomenclature
HGNC (Hugo)FABP3   3557
Cards
Entrez_Gene (NCBI)FABP3  2170  fatty acid binding protein 3
AliasesFABP11; H-FABP; M-FABP; MDGI; 
O-FABP
GeneCards (Weizmann)FABP3
Ensembl hg19 (Hinxton)ENSG00000121769 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000121769 [Gene_View]  ENSG00000121769 [Sequence]  chr1:31365253-31373288 [Contig_View]  FABP3 [Vega]
ICGC DataPortalENSG00000121769
TCGA cBioPortalFABP3
AceView (NCBI)FABP3
Genatlas (Paris)FABP3
WikiGenes2170
SOURCE (Princeton)FABP3
Genetics Home Reference (NIH)FABP3
Genomic and cartography
GoldenPath hg38 (UCSC)FABP3  -     chr1:31365253-31373288 -  1p35.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)FABP3  -     1p35.2   [Description]    (hg19-Feb_2009)
GoldenPathFABP3 - 1p35.2 [CytoView hg19]  FABP3 - 1p35.2 [CytoView hg38]
ImmunoBaseENSG00000121769
Mapping of homologs : NCBIFABP3 [Mapview hg19]  FABP3 [Mapview hg38]
OMIM134651   
Gene and transcription
Genbank (Entrez)AI494244 AK314122 BC007021 BF576953 BI752278
RefSeq transcript (Entrez)NM_001320996 NM_004102
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)FABP3
Cluster EST : UnigeneHs.657242 [ NCBI ]
CGAP (NCI)Hs.657242
Alternative Splicing GalleryENSG00000121769
Gene ExpressionFABP3 [ NCBI-GEO ]   FABP3 [ EBI - ARRAY_EXPRESS ]   FABP3 [ SEEK ]   FABP3 [ MEM ]
Gene Expression Viewer (FireBrowse)FABP3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2170
GTEX Portal (Tissue expression)FABP3
Human Protein AtlasENSG00000121769-FABP3 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP05413   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP05413  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP05413
Splice isoforms : SwissVarP05413
PhosPhoSitePlusP05413
Domaine pattern : Prosite (Expaxy)FABP (PS00214)   
Domains : Interpro (EBI)Calycin    Fatty_acid-bd    ILBP    Lipocln_cytosolic_FA-bd_dom   
Domain families : Pfam (Sanger)Lipocalin (PF00061)   
Domain families : Pfam (NCBI)pfam00061   
Conserved Domain (NCBI)FABP3
DMDM Disease mutations2170
Blocks (Seattle)FABP3
PDB (RSDB)1G5W    1HMR    1HMS    1HMT    2HMB    3RSW    3WBG    3WVM    3WXQ    4TJZ    4TKB    4TKH    4TKJ    4WBK    5B27    5B28    5B29    5CE4    5HZ9   
PDB Europe1G5W    1HMR    1HMS    1HMT    2HMB    3RSW    3WBG    3WVM    3WXQ    4TJZ    4TKB    4TKH    4TKJ    4WBK    5B27    5B28    5B29    5CE4    5HZ9   
PDB (PDBSum)1G5W    1HMR    1HMS    1HMT    2HMB    3RSW    3WBG    3WVM    3WXQ    4TJZ    4TKB    4TKH    4TKJ    4WBK    5B27    5B28    5B29    5CE4    5HZ9   
PDB (IMB)1G5W    1HMR    1HMS    1HMT    2HMB    3RSW    3WBG    3WVM    3WXQ    4TJZ    4TKB    4TKH    4TKJ    4WBK    5B27    5B28    5B29    5CE4    5HZ9   
Structural Biology KnowledgeBase1G5W    1HMR    1HMS    1HMT    2HMB    3RSW    3WBG    3WVM    3WXQ    4TJZ    4TKB    4TKH    4TKJ    4WBK    5B27    5B28    5B29    5CE4    5HZ9   
SCOP (Structural Classification of Proteins)1G5W    1HMR    1HMS    1HMT    2HMB    3RSW    3WBG    3WVM    3WXQ    4TJZ    4TKB    4TKH    4TKJ    4WBK    5B27    5B28    5B29    5CE4    5HZ9   
CATH (Classification of proteins structures)1G5W    1HMR    1HMS    1HMT    2HMB    3RSW    3WBG    3WVM    3WXQ    4TJZ    4TKB    4TKH    4TKJ    4WBK    5B27    5B28    5B29    5CE4    5HZ9   
SuperfamilyP05413
Human Protein Atlas [tissue]ENSG00000121769-FABP3 [tissue]
Peptide AtlasP05413
HPRD00613
IPIIPI00219684   
Protein Interaction databases
DIP (DOE-UCLA)P05413
IntAct (EBI)P05413
FunCoupENSG00000121769
BioGRIDFABP3
STRING (EMBL)FABP3
ZODIACFABP3
Ontologies - Pathways
QuickGOP05413
Ontology : AmiGOlong-chain fatty acid transporter activity  protein binding  extracellular space  extracellular space  cytosol  fatty acid metabolic process  cytoskeletal protein binding  negative regulation of cell proliferation  long-chain fatty acid transport  sarcoplasm  triglyceride catabolic process  intracellular lipid transport  response to insulin  long-chain fatty acid binding  response to drug  cholesterol homeostasis  regulation of fatty acid oxidation  icosatetraenoic acid binding  phospholipid homeostasis  extracellular exosome  oleic acid binding  response to fatty acid  positive regulation of phospholipid biosynthetic process  positive regulation of long-chain fatty acid import into cell  regulation of phosphatidylcholine biosynthetic process  
Ontology : EGO-EBIlong-chain fatty acid transporter activity  protein binding  extracellular space  extracellular space  cytosol  fatty acid metabolic process  cytoskeletal protein binding  negative regulation of cell proliferation  long-chain fatty acid transport  sarcoplasm  triglyceride catabolic process  intracellular lipid transport  response to insulin  long-chain fatty acid binding  response to drug  cholesterol homeostasis  regulation of fatty acid oxidation  icosatetraenoic acid binding  phospholipid homeostasis  extracellular exosome  oleic acid binding  response to fatty acid  positive regulation of phospholipid biosynthetic process  positive regulation of long-chain fatty acid import into cell  regulation of phosphatidylcholine biosynthetic process  
Pathways : KEGGPPAR signaling pathway   
NDEx NetworkFABP3
Atlas of Cancer Signalling NetworkFABP3
Wikipedia pathwaysFABP3
Orthology - Evolution
OrthoDB2170
GeneTree (enSembl)ENSG00000121769
Phylogenetic Trees/Animal Genes : TreeFamFABP3
HOGENOMP05413
Homologs : HomoloGeneFABP3
Homology/Alignments : Family Browser (UCSC)FABP3
Gene fusions - Rearrangements
Fusion : MitelmanZCCHC17/FABP3 [1p35.2/1p35.2]  [t(1;1)(p35;p35)]  
Fusion PortalZCCHC17 1p35.2 FABP3 1p35.2 GBM
Fusion : QuiverFABP3
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerFABP3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)FABP3
dbVarFABP3
ClinVarFABP3
1000_GenomesFABP3 
Exome Variant ServerFABP3
ExAC (Exome Aggregation Consortium)ENSG00000121769
GNOMAD BrowserENSG00000121769
Varsome BrowserFABP3
Genetic variants : HAPMAP2170
Genomic Variants (DGV)FABP3 [DGVbeta]
DECIPHERFABP3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisFABP3 
Mutations
ICGC Data PortalFABP3 
TCGA Data PortalFABP3 
Broad Tumor PortalFABP3
OASIS PortalFABP3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICFABP3  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DFABP3
Mutations and Diseases : HGMDFABP3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch FABP3
DgiDB (Drug Gene Interaction Database)FABP3
DoCM (Curated mutations)FABP3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)FABP3 (select a term)
intoGenFABP3
Cancer3DFABP3(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM134651   
Orphanet
DisGeNETFABP3
MedgenFABP3
Genetic Testing Registry FABP3
NextProtP05413 [Medical]
TSGene2170
GENETestsFABP3
Target ValidationFABP3
Huge Navigator FABP3 [HugePedia]
snp3D : Map Gene to Disease2170
BioCentury BCIQFABP3
ClinGenFABP3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD2170
Chemical/Pharm GKB GenePA27958
Clinical trialFABP3
Miscellaneous
canSAR (ICR)FABP3 (select the gene name)
DataMed IndexFABP3
Probes
Litterature
PubMed137 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineFABP3
EVEXFABP3
GoPubMedFABP3
iHOPFABP3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Aug 12 15:33:31 CEST 2019
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