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FABP4 (fatty acid binding protein 4)

Identity

Alias_symbol (synonym)A-FABP
aP2
Other aliasAFABP
ALBP
HEL-S-104
HGNC (Hugo) FABP4
LocusID (NCBI) 2167
Atlas_Id 46385
Location 8q21.13  [Link to chromosome band 8q21]
Location_base_pair Starts at 82390732 and ends at 82395473 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
FABP4 (8q21.13) / PMP22 (17p12)FABP4 (8q21.13) / SEMA3C (7q21.11)METTL17 (14q11.2) / FABP4 (8q21.13)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)FABP4   3559
Cards
Entrez_Gene (NCBI)FABP4  2167  fatty acid binding protein 4
AliasesA-FABP; AFABP; ALBP; HEL-S-104; 
aP2
GeneCards (Weizmann)FABP4
Ensembl hg19 (Hinxton)ENSG00000170323 [Gene_View]  chr8:82390732-82395473 [Contig_View]  FABP4 [Vega]
Ensembl hg38 (Hinxton)ENSG00000170323 [Gene_View]  chr8:82390732-82395473 [Contig_View]  FABP4 [Vega]
ICGC DataPortalENSG00000170323
TCGA cBioPortalFABP4
AceView (NCBI)FABP4
Genatlas (Paris)FABP4
WikiGenes2167
SOURCE (Princeton)FABP4
Genetics Home Reference (NIH)FABP4
Genomic and cartography
GoldenPath hg19 (UCSC)FABP4  -     chr8:82390732-82395473 -  8q21.13   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)FABP4  -     8q21.13   [Description]    (hg38-Dec_2013)
EnsemblFABP4 - 8q21.13 [CytoView hg19]  FABP4 - 8q21.13 [CytoView hg38]
Mapping of homologs : NCBIFABP4 [Mapview hg19]  FABP4 [Mapview hg38]
OMIM600434   
Gene and transcription
Genbank (Entrez)BC003672 BQ880795 BT006809 CD000452 CR456903
RefSeq transcript (Entrez)NM_001442
RefSeq genomic (Entrez)NC_000008 NC_018919 NT_008183 NW_004929339
Consensus coding sequences : CCDS (NCBI)FABP4
Cluster EST : UnigeneHs.391561 [ NCBI ]
CGAP (NCI)Hs.391561
Alternative Splicing GalleryENSG00000170323
Gene ExpressionFABP4 [ NCBI-GEO ]   FABP4 [ EBI - ARRAY_EXPRESS ]   FABP4 [ SEEK ]   FABP4 [ MEM ]
Gene Expression Viewer (FireBrowse)FABP4 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2167
GTEX Portal (Tissue expression)FABP4
Protein : pattern, domain, 3D structure
UniProt/SwissProtP15090   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP15090  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP15090
Splice isoforms : SwissVarP15090
PhosPhoSitePlusP15090
Domaine pattern : Prosite (Expaxy)FABP (PS00214)   
Domains : Interpro (EBI)Calycin    Calycin-like    FABP4    Fatty_acid-bd    iLBP    Lipocln_cytosolic_FA-bd_dom   
Domain families : Pfam (Sanger)Lipocalin (PF00061)   
Domain families : Pfam (NCBI)pfam00061   
Conserved Domain (NCBI)FABP4
DMDM Disease mutations2167
Blocks (Seattle)FABP4
PDB (SRS)1TOU    1TOW    2HNX    2NNQ    3FR2    3FR4    3FR5    3P6C    3P6D    3P6E    3P6F    3P6G    3P6H    3Q6L    3RZY    4NNS    4NNT   
PDB (PDBSum)1TOU    1TOW    2HNX    2NNQ    3FR2    3FR4    3FR5    3P6C    3P6D    3P6E    3P6F    3P6G    3P6H    3Q6L    3RZY    4NNS    4NNT   
PDB (IMB)1TOU    1TOW    2HNX    2NNQ    3FR2    3FR4    3FR5    3P6C    3P6D    3P6E    3P6F    3P6G    3P6H    3Q6L    3RZY    4NNS    4NNT   
PDB (RSDB)1TOU    1TOW    2HNX    2NNQ    3FR2    3FR4    3FR5    3P6C    3P6D    3P6E    3P6F    3P6G    3P6H    3Q6L    3RZY    4NNS    4NNT   
Structural Biology KnowledgeBase1TOU    1TOW    2HNX    2NNQ    3FR2    3FR4    3FR5    3P6C    3P6D    3P6E    3P6F    3P6G    3P6H    3Q6L    3RZY    4NNS    4NNT   
SCOP (Structural Classification of Proteins)1TOU    1TOW    2HNX    2NNQ    3FR2    3FR4    3FR5    3P6C    3P6D    3P6E    3P6F    3P6G    3P6H    3Q6L    3RZY    4NNS    4NNT   
CATH (Classification of proteins structures)1TOU    1TOW    2HNX    2NNQ    3FR2    3FR4    3FR5    3P6C    3P6D    3P6E    3P6F    3P6G    3P6H    3Q6L    3RZY    4NNS    4NNT   
SuperfamilyP15090
Human Protein AtlasENSG00000170323
Peptide AtlasP15090
HPRD02698
IPIIPI00215746   IPI00974290   
Protein Interaction databases
DIP (DOE-UCLA)P15090
IntAct (EBI)P15090
FunCoupENSG00000170323
BioGRIDFABP4
STRING (EMBL)FABP4
ZODIACFABP4
Ontologies - Pathways
QuickGOP15090
Ontology : AmiGOcytokine production  transporter activity  fatty acid binding  nucleus  cytoplasm  cytoplasm  lipid particle  cytosol  negative regulation of protein kinase activity  transport  triglyceride catabolic process  cholesterol homeostasis  negative regulation of transcription, DNA-templated  positive regulation of inflammatory response  white fat cell differentiation  brown fat cell differentiation  extracellular exosome  cellular response to lithium ion  
Ontology : EGO-EBIcytokine production  transporter activity  fatty acid binding  nucleus  cytoplasm  cytoplasm  lipid particle  cytosol  negative regulation of protein kinase activity  transport  triglyceride catabolic process  cholesterol homeostasis  negative regulation of transcription, DNA-templated  positive regulation of inflammatory response  white fat cell differentiation  brown fat cell differentiation  extracellular exosome  cellular response to lithium ion  
Pathways : KEGGPPAR signaling pathway   
NDEx NetworkFABP4
Atlas of Cancer Signalling NetworkFABP4
Wikipedia pathwaysFABP4
Orthology - Evolution
OrthoDB2167
GeneTree (enSembl)ENSG00000170323
Phylogenetic Trees/Animal Genes : TreeFamFABP4
HOVERGENP15090
HOGENOMP15090
Homologs : HomoloGeneFABP4
Homology/Alignments : Family Browser (UCSC)FABP4
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerFABP4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)FABP4
dbVarFABP4
ClinVarFABP4
1000_GenomesFABP4 
Exome Variant ServerFABP4
ExAC (Exome Aggregation Consortium)FABP4 (select the gene name)
Genetic variants : HAPMAP2167
Genomic Variants (DGV)FABP4 [DGVbeta]
DECIPHER (Syndromes)8:82390732-82395473  ENSG00000170323
CONAN: Copy Number AnalysisFABP4 
Mutations
ICGC Data PortalFABP4 
TCGA Data PortalFABP4 
Broad Tumor PortalFABP4
OASIS PortalFABP4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICFABP4  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDFABP4
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch FABP4
DgiDB (Drug Gene Interaction Database)FABP4
DoCM (Curated mutations)FABP4 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)FABP4 (select a term)
intoGenFABP4
Cancer3DFABP4(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM600434   
Orphanet
MedgenFABP4
Genetic Testing Registry FABP4
NextProtP15090 [Medical]
TSGene2167
GENETestsFABP4
Huge Navigator FABP4 [HugePedia]
snp3D : Map Gene to Disease2167
BioCentury BCIQFABP4
ClinGenFABP4
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD2167
Chemical/Pharm GKB GenePA27960
Clinical trialFABP4
Miscellaneous
canSAR (ICR)FABP4 (select the gene name)
Probes
Litterature
PubMed167 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineFABP4
EVEXFABP4
GoPubMedFABP4
iHOPFABP4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 13:05:18 CET 2017

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