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FAF2 (Fas associated factor family member 2)

Identity

Alias_namesUBXD8
UBX domain containing 8
Alias_symbol (synonym)ETEA
KIAA0887
UBXN3B
Other alias
HGNC (Hugo) FAF2
LocusID (NCBI) 23197
Atlas_Id 62974
Location 5q35.2  [Link to chromosome band 5q35]
Location_base_pair Starts at 176448355 and ends at 176510074 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
DSG2 (18q12.1) / FAF2 (5q35.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)FAF2   24666
Cards
Entrez_Gene (NCBI)FAF2  23197  Fas associated factor family member 2
AliasesETEA; UBXD8; UBXN3B
GeneCards (Weizmann)FAF2
Ensembl hg19 (Hinxton)ENSG00000113194 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000113194 [Gene_View]  chr5:176448355-176510074 [Contig_View]  FAF2 [Vega]
ICGC DataPortalENSG00000113194
TCGA cBioPortalFAF2
AceView (NCBI)FAF2
Genatlas (Paris)FAF2
WikiGenes23197
SOURCE (Princeton)FAF2
Genetics Home Reference (NIH)FAF2
Genomic and cartography
GoldenPath hg38 (UCSC)FAF2  -     chr5:176448355-176510074 +  5q35.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)FAF2  -     5q35.2   [Description]    (hg19-Feb_2009)
EnsemblFAF2 - 5q35.2 [CytoView hg19]  FAF2 - 5q35.2 [CytoView hg38]
Mapping of homologs : NCBIFAF2 [Mapview hg19]  FAF2 [Mapview hg38]
OMIM616935   
Gene and transcription
Genbank (Entrez)AB020694 AB088120 AK304346 AL706430 BC001069
RefSeq transcript (Entrez)NM_014613
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)FAF2
Cluster EST : UnigeneHs.484242 [ NCBI ]
CGAP (NCI)Hs.484242
Alternative Splicing GalleryENSG00000113194
Gene ExpressionFAF2 [ NCBI-GEO ]   FAF2 [ EBI - ARRAY_EXPRESS ]   FAF2 [ SEEK ]   FAF2 [ MEM ]
Gene Expression Viewer (FireBrowse)FAF2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)23197
GTEX Portal (Tissue expression)FAF2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96CS3   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96CS3  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96CS3
Splice isoforms : SwissVarQ96CS3
PhosPhoSitePlusQ96CS3
Domaine pattern : Prosite (Expaxy)UBX (PS50033)   
Domains : Interpro (EBI)Thioredoxin-like_fold    UAS    UBA-like    Ubiquitin-rel_dom    UBX_dom   
Domain families : Pfam (Sanger)UBX (PF00789)   
Domain families : Pfam (NCBI)pfam00789   
Domain families : Smart (EMBL)UAS (SM00594)  
Conserved Domain (NCBI)FAF2
DMDM Disease mutations23197
Blocks (Seattle)FAF2
PDB (SRS)2DAM   
PDB (PDBSum)2DAM   
PDB (IMB)2DAM   
PDB (RSDB)2DAM   
Structural Biology KnowledgeBase2DAM   
SCOP (Structural Classification of Proteins)2DAM   
CATH (Classification of proteins structures)2DAM   
SuperfamilyQ96CS3
Human Protein AtlasENSG00000113194
Peptide AtlasQ96CS3
HPRD16870
IPIIPI00172656   IPI00967358   
Protein Interaction databases
DIP (DOE-UCLA)Q96CS3
IntAct (EBI)Q96CS3
FunCoupENSG00000113194
BioGRIDFAF2
STRING (EMBL)FAF2
ZODIACFAF2
Ontologies - Pathways
QuickGOQ96CS3
Ontology : AmiGOprotein binding  extracellular region  endoplasmic reticulum  lipid particle  response to unfolded protein  ubiquitin-dependent ERAD pathway  retrograde protein transport, ER to cytosol  ubiquitin protein ligase binding  VCP-NPL4-UFD1 AAA ATPase complex  lipid particle organization  lipase binding  azurophil granule lumen  negative regulation of catalytic activity  ubiquitin binding  neutrophil degranulation  lipase inhibitor activity  
Ontology : EGO-EBIprotein binding  extracellular region  endoplasmic reticulum  lipid particle  response to unfolded protein  ubiquitin-dependent ERAD pathway  retrograde protein transport, ER to cytosol  ubiquitin protein ligase binding  VCP-NPL4-UFD1 AAA ATPase complex  lipid particle organization  lipase binding  azurophil granule lumen  negative regulation of catalytic activity  ubiquitin binding  neutrophil degranulation  lipase inhibitor activity  
NDEx NetworkFAF2
Atlas of Cancer Signalling NetworkFAF2
Wikipedia pathwaysFAF2
Orthology - Evolution
OrthoDB23197
GeneTree (enSembl)ENSG00000113194
Phylogenetic Trees/Animal Genes : TreeFamFAF2
HOVERGENQ96CS3
HOGENOMQ96CS3
Homologs : HomoloGeneFAF2
Homology/Alignments : Family Browser (UCSC)FAF2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerFAF2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)FAF2
dbVarFAF2
ClinVarFAF2
1000_GenomesFAF2 
Exome Variant ServerFAF2
ExAC (Exome Aggregation Consortium)FAF2 (select the gene name)
Genetic variants : HAPMAP23197
Genomic Variants (DGV)FAF2 [DGVbeta]
DECIPHERFAF2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisFAF2 
Mutations
ICGC Data PortalFAF2 
TCGA Data PortalFAF2 
Broad Tumor PortalFAF2
OASIS PortalFAF2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICFAF2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDFAF2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch FAF2
DgiDB (Drug Gene Interaction Database)FAF2
DoCM (Curated mutations)FAF2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)FAF2 (select a term)
intoGenFAF2
Cancer3DFAF2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM616935   
Orphanet
MedgenFAF2
Genetic Testing Registry FAF2
NextProtQ96CS3 [Medical]
TSGene23197
GENETestsFAF2
Target ValidationFAF2
Huge Navigator FAF2 [HugePedia]
snp3D : Map Gene to Disease23197
BioCentury BCIQFAF2
ClinGenFAF2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD23197
Chemical/Pharm GKB GenePA162385570
Clinical trialFAF2
Miscellaneous
canSAR (ICR)FAF2 (select the gene name)
Probes
Litterature
PubMed50 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineFAF2
EVEXFAF2
GoPubMedFAF2
iHOPFAF2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 15:47:39 CEST 2017

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