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FAM126A (family with sequence similarity 126 member A)

Identity

Alias (NCBI)DRCTNNB1A
HCC
HLD5
HYCC1
HGNC (Hugo) FAM126A
HGNC Alias symbDRCTNNB1A
HCC
HYCC1
hyccin
HGNC Alias namedown regulated by Ctnnb1, a
HGNC Previous namefamily with sequence similarity 126, member A
LocusID (NCBI) 84668
Atlas_Id 63010
Location 7p15.3  [Link to chromosome band 7p15]
Location_base_pair Starts at 22934231 and ends at 23014130 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
FAM126A (7p15.3) / HIBADH (7p15.2)FAM126A (7p15.3) / TRO (Xp11.21)PDLIM5 (4q22.3) / FAM126A (7p15.3)
RBBP8 (18q11.2) / FAM126A (7p15.3)STXBP5 (6q24.3) / FAM126A (7p15.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)FAM126A   24587
Cards
Entrez_Gene (NCBI)FAM126A    family with sequence similarity 126 member A
AliasesDRCTNNB1A; HCC; HLD5; HYCC1
GeneCards (Weizmann)FAM126A
Ensembl hg19 (Hinxton)ENSG00000122591 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000122591 [Gene_View]  ENSG00000122591 [Sequence]  chr7:22934231-23014130 [Contig_View]  FAM126A [Vega]
ICGC DataPortalENSG00000122591
TCGA cBioPortalFAM126A
AceView (NCBI)FAM126A
Genatlas (Paris)FAM126A
SOURCE (Princeton)FAM126A
Genetics Home Reference (NIH)FAM126A
Genomic and cartography
GoldenPath hg38 (UCSC)FAM126A  -     chr7:22934231-23014130 -  7p15.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)FAM126A  -     7p15.3   [Description]    (hg19-Feb_2009)
GoldenPathFAM126A - 7p15.3 [CytoView hg19]  FAM126A - 7p15.3 [CytoView hg38]
ImmunoBaseENSG00000122591
Genome Data Viewer NCBIFAM126A [Mapview hg19]  
OMIM610531   610532   
Gene and transcription
Genbank (Entrez)AA811006 AB030241 AK054887 AK056319 AK057686
RefSeq transcript (Entrez)NM_001363466 NM_001363467 NM_032581
Consensus coding sequences : CCDS (NCBI)FAM126A
Gene ExpressionFAM126A [ NCBI-GEO ]   FAM126A [ EBI - ARRAY_EXPRESS ]   FAM126A [ SEEK ]   FAM126A [ MEM ]
Gene Expression Viewer (FireBrowse)FAM126A [ Firebrowse - Broad ]
GenevisibleExpression of FAM126A in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)84668
GTEX Portal (Tissue expression)FAM126A
Human Protein AtlasENSG00000122591-FAM126A [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9BYI3   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9BYI3  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9BYI3
PhosPhoSitePlusQ9BYI3
Domains : Interpro (EBI)Hyccin   
Domain families : Pfam (Sanger)Hyccin (PF09790)   
Domain families : Pfam (NCBI)pfam09790   
Conserved Domain (NCBI)FAM126A
PDB (RSDB)5DSE    6BQ1   
PDB Europe5DSE    6BQ1   
PDB (PDBSum)5DSE    6BQ1   
PDB (IMB)5DSE    6BQ1   
Structural Biology KnowledgeBase5DSE    6BQ1   
SCOP (Structural Classification of Proteins)5DSE    6BQ1   
CATH (Classification of proteins structures)5DSE    6BQ1   
SuperfamilyQ9BYI3
AlphaFold pdb e-kbQ9BYI3   
Human Protein Atlas [tissue]ENSG00000122591-FAM126A [tissue]
HPRD16837
Protein Interaction databases
DIP (DOE-UCLA)Q9BYI3
IntAct (EBI)Q9BYI3
BioGRIDFAM126A
STRING (EMBL)FAM126A
ZODIACFAM126A
Ontologies - Pathways
QuickGOQ9BYI3
Ontology : AmiGOprotein binding  cytosol  plasma membrane  plasma membrane  myelination  phosphatidylinositol phosphate biosynthetic process  phosphatidylinositol phosphate biosynthetic process  protein localization to plasma membrane  protein localization to plasma membrane  
Ontology : EGO-EBIprotein binding  cytosol  plasma membrane  plasma membrane  myelination  phosphatidylinositol phosphate biosynthetic process  phosphatidylinositol phosphate biosynthetic process  protein localization to plasma membrane  protein localization to plasma membrane  
NDEx NetworkFAM126A
Atlas of Cancer Signalling NetworkFAM126A
Wikipedia pathwaysFAM126A
Orthology - Evolution
OrthoDB84668
GeneTree (enSembl)ENSG00000122591
Phylogenetic Trees/Animal Genes : TreeFamFAM126A
Homologs : HomoloGeneFAM126A
Homology/Alignments : Family Browser (UCSC)FAM126A
Gene fusions - Rearrangements
Fusion : QuiverFAM126A
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerFAM126A [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)FAM126A
dbVarFAM126A
ClinVarFAM126A
MonarchFAM126A
1000_GenomesFAM126A 
Exome Variant ServerFAM126A
GNOMAD BrowserENSG00000122591
Varsome BrowserFAM126A
ACMGFAM126A variants
VarityQ9BYI3
Genomic Variants (DGV)FAM126A [DGVbeta]
DECIPHERFAM126A [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisFAM126A 
Mutations
ICGC Data PortalFAM126A 
TCGA Data PortalFAM126A 
Broad Tumor PortalFAM126A
OASIS PortalFAM126A [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICFAM126A  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DFAM126A
Mutations and Diseases : HGMDFAM126A
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaFAM126A
DgiDB (Drug Gene Interaction Database)FAM126A
DoCM (Curated mutations)FAM126A
CIViC (Clinical Interpretations of Variants in Cancer)FAM126A
Cancer3DFAM126A
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM610531    610532   
Orphanet11630   
DisGeNETFAM126A
MedgenFAM126A
Genetic Testing Registry FAM126A
NextProtQ9BYI3 [Medical]
GENETestsFAM126A
Target ValidationFAM126A
Huge Navigator FAM126A [HugePedia]
ClinGenFAM126A
Clinical trials, drugs, therapy
MyCancerGenomeFAM126A
Protein Interactions : CTDFAM126A
Pharm GKB GenePA162385852
PharosQ9BYI3
Clinical trialFAM126A
Miscellaneous
canSAR (ICR)FAM126A
HarmonizomeFAM126A
DataMed IndexFAM126A
Probes
Litterature
PubMed33 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXFAM126A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:49:29 CEST 2021

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