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FAM132A (family with sequence similarity 132 member A)

Identity

Alias_namesC1QDC2
C1q domain containing 2
family with sequence similarity 132, member A
Alias_symbol (synonym)MGC105127
C1QTNF12
CTRP12
Other alias
HGNC (Hugo) FAM132A
LocusID (NCBI) 388581
Atlas_Id 53129
Location 1p36.33  [Link to chromosome band 1p36]
Location_base_pair Starts at 1177826 and ends at 1182102 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
RLF (1p34.2) / FAM132A (1p36.33)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  Lung: Translocations in Small Cell Carcinoma


External links

Nomenclature
HGNC (Hugo)FAM132A   32308
Cards
Entrez_Gene (NCBI)FAM132A  388581  family with sequence similarity 132 member A
AliasesC1QDC2; C1QTNF12; CTRP12
GeneCards (Weizmann)FAM132A
Ensembl hg19 (Hinxton)ENSG00000184163 [Gene_View]  chr1:1177826-1182102 [Contig_View]  FAM132A [Vega]
Ensembl hg38 (Hinxton)ENSG00000184163 [Gene_View]  chr1:1177826-1182102 [Contig_View]  FAM132A [Vega]
ICGC DataPortalENSG00000184163
TCGA cBioPortalFAM132A
AceView (NCBI)FAM132A
Genatlas (Paris)FAM132A
WikiGenes388581
SOURCE (Princeton)FAM132A
Genetics Home Reference (NIH)FAM132A
Genomic and cartography
GoldenPath hg19 (UCSC)FAM132A  -     chr1:1177826-1182102 -  1p36.33   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)FAM132A  -     1p36.33   [Description]    (hg38-Dec_2013)
EnsemblFAM132A - 1p36.33 [CytoView hg19]  FAM132A - 1p36.33 [CytoView hg38]
Mapping of homologs : NCBIFAM132A [Mapview hg19]  FAM132A [Mapview hg38]
OMIM616593   
Gene and transcription
Genbank (Entrez)AW873053 BC089443
RefSeq transcript (Entrez)NM_001014980
RefSeq genomic (Entrez)NC_000001 NC_018912 NT_032977 NW_004929288
Consensus coding sequences : CCDS (NCBI)FAM132A
Cluster EST : UnigeneHs.197613 [ NCBI ]
CGAP (NCI)Hs.197613
Alternative Splicing GalleryENSG00000184163
Gene ExpressionFAM132A [ NCBI-GEO ]   FAM132A [ EBI - ARRAY_EXPRESS ]   FAM132A [ SEEK ]   FAM132A [ MEM ]
Gene Expression Viewer (FireBrowse)FAM132A [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)388581
GTEX Portal (Tissue expression)FAM132A
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ5T7M4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ5T7M4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ5T7M4
Splice isoforms : SwissVarQ5T7M4
PhosPhoSitePlusQ5T7M4
Domaine pattern : Prosite (Expaxy)C1Q (PS50871)   
Domains : Interpro (EBI)C1q_dom    Tumour_necrosis_fac-like_dom   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)FAM132A
DMDM Disease mutations388581
Blocks (Seattle)FAM132A
SuperfamilyQ5T7M4
Human Protein AtlasENSG00000184163
Peptide AtlasQ5T7M4
IPIIPI00373976   
Protein Interaction databases
DIP (DOE-UCLA)Q5T7M4
IntAct (EBI)Q5T7M4
FunCoupENSG00000184163
BioGRIDFAM132A
STRING (EMBL)FAM132A
ZODIACFAM132A
Ontologies - Pathways
QuickGOQ5T7M4
Ontology : AmiGOhormone activity  extracellular region  extracellular space  positive regulation of insulin secretion involved in cellular response to glucose stimulus  negative regulation of gluconeogenesis  regulation of glucose import  positive regulation of glucose import  positive regulation of insulin receptor signaling pathway  negative regulation of inflammatory response  positive regulation of protein kinase B signaling  
Ontology : EGO-EBIhormone activity  extracellular region  extracellular space  positive regulation of insulin secretion involved in cellular response to glucose stimulus  negative regulation of gluconeogenesis  regulation of glucose import  positive regulation of glucose import  positive regulation of insulin receptor signaling pathway  negative regulation of inflammatory response  positive regulation of protein kinase B signaling  
NDEx NetworkFAM132A
Atlas of Cancer Signalling NetworkFAM132A
Wikipedia pathwaysFAM132A
Orthology - Evolution
OrthoDB388581
GeneTree (enSembl)ENSG00000184163
Phylogenetic Trees/Animal Genes : TreeFamFAM132A
HOVERGENQ5T7M4
HOGENOMQ5T7M4
Homologs : HomoloGeneFAM132A
Homology/Alignments : Family Browser (UCSC)FAM132A
Gene fusions - Rearrangements
Fusion : MitelmanRLF/FAM132A [1p34.2/1p36.33]  [t(1;1)(p34;p36)]  
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerFAM132A [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)FAM132A
dbVarFAM132A
ClinVarFAM132A
1000_GenomesFAM132A 
Exome Variant ServerFAM132A
ExAC (Exome Aggregation Consortium)FAM132A (select the gene name)
Genetic variants : HAPMAP388581
Genomic Variants (DGV)FAM132A [DGVbeta]
DECIPHER (Syndromes)1:1177826-1182102  ENSG00000184163
CONAN: Copy Number AnalysisFAM132A 
Mutations
ICGC Data PortalFAM132A 
TCGA Data PortalFAM132A 
Broad Tumor PortalFAM132A
OASIS PortalFAM132A [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICFAM132A  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDFAM132A
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch FAM132A
DgiDB (Drug Gene Interaction Database)FAM132A
DoCM (Curated mutations)FAM132A (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)FAM132A (select a term)
intoGenFAM132A
Cancer3DFAM132A(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM616593   
Orphanet
MedgenFAM132A
Genetic Testing Registry FAM132A
NextProtQ5T7M4 [Medical]
TSGene388581
GENETestsFAM132A
Huge Navigator FAM132A [HugePedia]
snp3D : Map Gene to Disease388581
BioCentury BCIQFAM132A
ClinGenFAM132A
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD388581
Chemical/Pharm GKB GenePA162386101
Clinical trialFAM132A
Miscellaneous
canSAR (ICR)FAM132A (select the gene name)
Probes
Litterature
PubMed6 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineFAM132A
EVEXFAM132A
GoPubMedFAM132A
iHOPFAM132A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 30 15:00:39 CEST 2017

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