FAM172A (family with sequence similarity 172 member A)

2014-04-01  

Identity

HGNC
LOCATION
5q15
LOCUSID
ALIAS
C5orf21,Toupee
FUSION GENES

Other Information

Locus ID:

NCBI: 83989
HGNC: 25365
Ensembl: ENSG00000113391

Variants:

dbSNP: 83989
ClinVar: 83989
TCGA: ENSG00000113391
COSMIC: FAM172A

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000113391ENST00000395965Q8WUF8
ENSG00000113391ENST00000395965A0A024RAL9
ENSG00000113391ENST00000502503E9PBM2
ENSG00000113391ENST00000505869Q8WUF8
ENSG00000113391ENST00000509163Q8WUF8
ENSG00000113391ENST00000509739B4DMI0

Expression (GTEx)

0
5
10
15
20
25
30

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
233144432013FAM172A induces S phase arrest of HepG2 cells via Notch 3.6
208184862010Identification of the novel protein FAM172A, and its up-regulation by high glucose in human aortic smooth muscle cells.5
201376232009[Molecular cloning of a novel gene, C5orf21 gene and its roles in diabetic macroangiopathy].4
265735602016FAM172A protein promotes the proliferation of human papillary thyroid carcinoma cells via the p38 mitogen-activated protein kinase pathway.4
266372242016FAM172A is a tumor suppressor in colorectal carcinoma.4
266768442016FAM172A modulates apoptosis and proliferation of colon cancer cells via STAT1 binding to its promoter.4
284404972017miR‑27a promotes proliferation, migration, and invasion of colorectal cancer by targeting FAM172A and acts as a diagnostic and prognostic biomarker.4
286189312017Detection of FAM172A expressed in circulating tumor cells is a feasible method to predict high-risk subgroups of colorectal cancer.3
210925152010[Effect of FAM172A protein on apoptosis and proliferation in HEK293 cells].1

Citation

Dessen P

FAM172A (family with sequence similarity 172 member A)

Atlas Genet Cytogenet Oncol Haematol. 2014-04-01

Online version: http://atlasgeneticsoncology.org/gene/53871/fam172a