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FAM175A (family with sequence similarity 175 member A)

Identity

Alias_namesCCDC98
coiled-coil domain containing 98
family with sequence similarity 175, member A
Alias_symbol (synonym)FLJ13614
ABRA1
ABRAXAS
Other alias
HGNC (Hugo) FAM175A
LocusID (NCBI) 84142
Atlas_Id 47568
Location 4q21.23  [Link to chromosome band 4q21]
Location_base_pair Starts at 84382094 and ends at 84406290 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
FAM175A (4q21.23) / HELQ (4q21.23)HELQ (4q21.23) / FAM175A (4q21.23)PI4KA (22q11.21) / FAM175A (4q21.23)
PI4KA 22q11.21 / FAM175A 4q21.23

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)FAM175A   25829
Cards
Entrez_Gene (NCBI)FAM175A  84142  family with sequence similarity 175 member A
AliasesABRA1; CCDC98
GeneCards (Weizmann)FAM175A
Ensembl hg19 (Hinxton)ENSG00000163322 [Gene_View]  chr4:84382094-84406290 [Contig_View]  FAM175A [Vega]
Ensembl hg38 (Hinxton)ENSG00000163322 [Gene_View]  chr4:84382094-84406290 [Contig_View]  FAM175A [Vega]
ICGC DataPortalENSG00000163322
TCGA cBioPortalFAM175A
AceView (NCBI)FAM175A
Genatlas (Paris)FAM175A
WikiGenes84142
SOURCE (Princeton)FAM175A
Genetics Home Reference (NIH)FAM175A
Genomic and cartography
GoldenPath hg19 (UCSC)FAM175A  -     chr4:84382094-84406290 -  4q21.23   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)FAM175A  -     4q21.23   [Description]    (hg38-Dec_2013)
EnsemblFAM175A - 4q21.23 [CytoView hg19]  FAM175A - 4q21.23 [CytoView hg38]
Mapping of homologs : NCBIFAM175A [Mapview hg19]  FAM175A [Mapview hg38]
OMIM611143   
Gene and transcription
Genbank (Entrez)AK021582 AK022704 AK023676 AY358576 BC016905
RefSeq transcript (Entrez)NM_139076
RefSeq genomic (Entrez)NC_000004 NC_018915 NT_016354 NW_004929320
Consensus coding sequences : CCDS (NCBI)FAM175A
Cluster EST : UnigeneHs.334772 [ NCBI ]
CGAP (NCI)Hs.334772
Alternative Splicing GalleryENSG00000163322
Gene ExpressionFAM175A [ NCBI-GEO ]   FAM175A [ EBI - ARRAY_EXPRESS ]   FAM175A [ SEEK ]   FAM175A [ MEM ]
Gene Expression Viewer (FireBrowse)FAM175A [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)84142
GTEX Portal (Tissue expression)FAM175A
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6UWZ7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6UWZ7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6UWZ7
Splice isoforms : SwissVarQ6UWZ7
PhosPhoSitePlusQ6UWZ7
Domains : Interpro (EBI)FAM175    FAM175_BRCA1-A_cplx_Abraxas_su   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)FAM175A
DMDM Disease mutations84142
Blocks (Seattle)FAM175A
PDB (SRS)4JLU    4U4A    4Y18    4Y2G   
PDB (PDBSum)4JLU    4U4A    4Y18    4Y2G   
PDB (IMB)4JLU    4U4A    4Y18    4Y2G   
PDB (RSDB)4JLU    4U4A    4Y18    4Y2G   
Structural Biology KnowledgeBase4JLU    4U4A    4Y18    4Y2G   
SCOP (Structural Classification of Proteins)4JLU    4U4A    4Y18    4Y2G   
CATH (Classification of proteins structures)4JLU    4U4A    4Y18    4Y2G   
SuperfamilyQ6UWZ7
Human Protein AtlasENSG00000163322
Peptide AtlasQ6UWZ7
HPRD08584
IPIIPI00030384   IPI00964056   IPI00386273   IPI00965417   IPI00964905   
Protein Interaction databases
DIP (DOE-UCLA)Q6UWZ7
IntAct (EBI)Q6UWZ7
FunCoupENSG00000163322
BioGRIDFAM175A
STRING (EMBL)FAM175A
ZODIACFAM175A
Ontologies - Pathways
QuickGOQ6UWZ7
Ontology : AmiGOprotein binding  nucleus  nucleoplasm  double-strand break repair  double-strand break repair via nonhomologous end joining  response to ionizing radiation  chromatin modification  G2 DNA damage checkpoint  polyubiquitin binding  positive regulation of DNA repair  BRCA1-A complex  
Ontology : EGO-EBIprotein binding  nucleus  nucleoplasm  double-strand break repair  double-strand break repair via nonhomologous end joining  response to ionizing radiation  chromatin modification  G2 DNA damage checkpoint  polyubiquitin binding  positive regulation of DNA repair  BRCA1-A complex  
NDEx NetworkFAM175A
Atlas of Cancer Signalling NetworkFAM175A
Wikipedia pathwaysFAM175A
Orthology - Evolution
OrthoDB84142
GeneTree (enSembl)ENSG00000163322
Phylogenetic Trees/Animal Genes : TreeFamFAM175A
HOVERGENQ6UWZ7
HOGENOMQ6UWZ7
Homologs : HomoloGeneFAM175A
Homology/Alignments : Family Browser (UCSC)FAM175A
Gene fusions - Rearrangements
Fusion : MitelmanPI4KA/FAM175A [22q11.21/4q21.23]  [t(4;22)(q21;q11)]  
Fusion: TCGAPI4KA 22q11.21 FAM175A 4q21.23 PRAD
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerFAM175A [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)FAM175A
dbVarFAM175A
ClinVarFAM175A
1000_GenomesFAM175A 
Exome Variant ServerFAM175A
ExAC (Exome Aggregation Consortium)FAM175A (select the gene name)
Genetic variants : HAPMAP84142
Genomic Variants (DGV)FAM175A [DGVbeta]
DECIPHER (Syndromes)4:84382094-84406290  ENSG00000163322
CONAN: Copy Number AnalysisFAM175A 
Mutations
ICGC Data PortalFAM175A 
TCGA Data PortalFAM175A 
Broad Tumor PortalFAM175A
OASIS PortalFAM175A [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICFAM175A  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDFAM175A
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch FAM175A
DgiDB (Drug Gene Interaction Database)FAM175A
DoCM (Curated mutations)FAM175A (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)FAM175A (select a term)
intoGenFAM175A
Cancer3DFAM175A(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611143   
Orphanet
MedgenFAM175A
Genetic Testing Registry FAM175A
NextProtQ6UWZ7 [Medical]
TSGene84142
GENETestsFAM175A
Huge Navigator FAM175A [HugePedia]
snp3D : Map Gene to Disease84142
BioCentury BCIQFAM175A
ClinGenFAM175A
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD84142
Chemical/Pharm GKB GenePA162387308
Clinical trialFAM175A
Miscellaneous
canSAR (ICR)FAM175A (select the gene name)
Probes
Litterature
PubMed41 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineFAM175A
EVEXFAM175A
GoPubMedFAM175A
iHOPFAM175A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 13:05:27 CET 2017

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