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FAM177A1 (family with sequence similarity 177 member A1)

Identity

Alias_namesC14orf24
chromosome 14 open reading frame 24
family with sequence similarity 177, member A1
Other alias
HGNC (Hugo) FAM177A1
LocusID (NCBI) 283635
Atlas_Id 63076
Location 14q13.2  [Link to chromosome band 14q13]
Location_base_pair Starts at 35044907 and ends at 35083383 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
EXT1 (8q24.11) / FAM177A1 (14q13.2)FAM177A1 (14q13.2) / FAM177A1 (14q13.2)FAM177A1 (14q13.2) / IQSEC3 (12p13.33)
KIAA0391 (14q13.2) / FAM177A1 (14q13.2)PTMS (12p13.31) / FAM177A1 (14q13.2)TTC6 (14q21.1) / FAM177A1 (14q13.2)
KIAA0391 FAM177A1TTC6 FAM177A1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 3 ]
  t(12;14)(p13;q13) FAM177A1/IQSEC3
t(14;14)(q13;q13) KIAA0391/FAM177A1
t(14;14)(q13;q21) TTC6/FAM177A1

External links

Nomenclature
HGNC (Hugo)FAM177A1   19829
Cards
Entrez_Gene (NCBI)FAM177A1  283635  family with sequence similarity 177 member A1
AliasesC14orf24
GeneCards (Weizmann)FAM177A1
Ensembl hg19 (Hinxton)ENSG00000151327 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000151327 [Gene_View]  chr14:35044907-35083383 [Contig_View]  FAM177A1 [Vega]
ICGC DataPortalENSG00000151327
TCGA cBioPortalFAM177A1
AceView (NCBI)FAM177A1
Genatlas (Paris)FAM177A1
WikiGenes283635
SOURCE (Princeton)FAM177A1
Genetics Home Reference (NIH)FAM177A1
Genomic and cartography
GoldenPath hg38 (UCSC)FAM177A1  -     chr14:35044907-35083383 +  14q13.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)FAM177A1  -     14q13.2   [Description]    (hg19-Feb_2009)
EnsemblFAM177A1 - 14q13.2 [CytoView hg19]  FAM177A1 - 14q13.2 [CytoView hg38]
Mapping of homologs : NCBIFAM177A1 [Mapview hg19]  FAM177A1 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AI148967 AK096173 AL833508 BC029559 BC040538
RefSeq transcript (Entrez)NM_001079519 NM_001289022 NM_173607
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)FAM177A1
Cluster EST : UnigeneHs.745141 [ NCBI ]
CGAP (NCI)Hs.745141
Alternative Splicing GalleryENSG00000151327
Gene ExpressionFAM177A1 [ NCBI-GEO ]   FAM177A1 [ EBI - ARRAY_EXPRESS ]   FAM177A1 [ SEEK ]   FAM177A1 [ MEM ]
Gene Expression Viewer (FireBrowse)FAM177A1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)283635
GTEX Portal (Tissue expression)FAM177A1
Human Protein AtlasENSG00000151327-FAM177A1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8N128   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8N128  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8N128
Splice isoforms : SwissVarQ8N128
PhosPhoSitePlusQ8N128
Domains : Interpro (EBI)FAM177   
Domain families : Pfam (Sanger)FAM177 (PF14774)   
Domain families : Pfam (NCBI)pfam14774   
Conserved Domain (NCBI)FAM177A1
DMDM Disease mutations283635
Blocks (Seattle)FAM177A1
SuperfamilyQ8N128
Human Protein Atlas [tissue]ENSG00000151327-FAM177A1 [tissue]
Peptide AtlasQ8N128
HPRD12644
IPIIPI00166051   IPI00748891   IPI01026022   IPI01025964   IPI01025345   IPI01025237   IPI01024796   
Protein Interaction databases
DIP (DOE-UCLA)Q8N128
IntAct (EBI)Q8N128
FunCoupENSG00000151327
BioGRIDFAM177A1
STRING (EMBL)FAM177A1
ZODIACFAM177A1
Ontologies - Pathways
QuickGOQ8N128
Ontology : AmiGO
Ontology : EGO-EBI
NDEx NetworkFAM177A1
Atlas of Cancer Signalling NetworkFAM177A1
Wikipedia pathwaysFAM177A1
Orthology - Evolution
OrthoDB283635
GeneTree (enSembl)ENSG00000151327
Phylogenetic Trees/Animal Genes : TreeFamFAM177A1
HOVERGENQ8N128
HOGENOMQ8N128
Homologs : HomoloGeneFAM177A1
Homology/Alignments : Family Browser (UCSC)FAM177A1
Gene fusions - Rearrangements
Fusion: TCGA_MDACCKIAA0391 FAM177A1
Fusion: TCGA_MDACCTTC6 FAM177A1
Fusion PortalKIAA0391 FAM177A1
Fusion PortalTTC6 FAM177A1
Fusion : QuiverFAM177A1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerFAM177A1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)FAM177A1
dbVarFAM177A1
ClinVarFAM177A1
1000_GenomesFAM177A1 
Exome Variant ServerFAM177A1
ExAC (Exome Aggregation Consortium)ENSG00000151327
GNOMAD BrowserENSG00000151327
Genetic variants : HAPMAP283635
Genomic Variants (DGV)FAM177A1 [DGVbeta]
DECIPHERFAM177A1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisFAM177A1 
Mutations
ICGC Data PortalFAM177A1 
TCGA Data PortalFAM177A1 
Broad Tumor PortalFAM177A1
OASIS PortalFAM177A1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICFAM177A1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDFAM177A1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch FAM177A1
DgiDB (Drug Gene Interaction Database)FAM177A1
DoCM (Curated mutations)FAM177A1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)FAM177A1 (select a term)
intoGenFAM177A1
Cancer3DFAM177A1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETFAM177A1
MedgenFAM177A1
Genetic Testing Registry FAM177A1
NextProtQ8N128 [Medical]
TSGene283635
GENETestsFAM177A1
Target ValidationFAM177A1
Huge Navigator FAM177A1 [HugePedia]
snp3D : Map Gene to Disease283635
BioCentury BCIQFAM177A1
ClinGenFAM177A1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD283635
Chemical/Pharm GKB GenePA162387378
Clinical trialFAM177A1
Miscellaneous
canSAR (ICR)FAM177A1 (select the gene name)
Probes
Litterature
PubMed8 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineFAM177A1
EVEXFAM177A1
GoPubMedFAM177A1
iHOPFAM177A1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri Feb 23 18:18:05 CET 2018
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