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FAM189B (family with sequence similarity 189 member B)

Identity

Alias_namesC1orf2
chromosome 1 open reading frame 2
family with sequence similarity 189, member B
Alias_symbol (synonym)cote1
Other aliasCOTE1
HGNC (Hugo) FAM189B
LocusID (NCBI) 10712
Atlas_Id 53469
Location 1q22  [Link to chromosome band 1q22]
Location_base_pair Starts at 155247205 and ends at 155255483 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
CAV2 (7q31.2) / FAM189B (1q22)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)FAM189B   1233
Cards
Entrez_Gene (NCBI)FAM189B  10712  family with sequence similarity 189 member B
AliasesC1orf2; COTE1
GeneCards (Weizmann)FAM189B
Ensembl hg19 (Hinxton)ENSG00000160767 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000160767 [Gene_View]  chr1:155247205-155255483 [Contig_View]  FAM189B [Vega]
ICGC DataPortalENSG00000160767
TCGA cBioPortalFAM189B
AceView (NCBI)FAM189B
Genatlas (Paris)FAM189B
WikiGenes10712
SOURCE (Princeton)FAM189B
Genetics Home Reference (NIH)FAM189B
Genomic and cartography
GoldenPath hg38 (UCSC)FAM189B  -     chr1:155247205-155255483 -  1q22   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)FAM189B  -     1q22   [Description]    (hg19-Feb_2009)
EnsemblFAM189B - 1q22 [CytoView hg19]  FAM189B - 1q22 [CytoView hg38]
Mapping of homologs : NCBIFAM189B [Mapview hg19]  FAM189B [Mapview hg38]
Gene and transcription
Genbank (Entrez)AF070550 AK093335 AL353941 BC006297 BC006493
RefSeq transcript (Entrez)NM_001267608 NM_006589 NM_198264
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)FAM189B
Cluster EST : UnigeneHs.348308 [ NCBI ]
CGAP (NCI)Hs.348308
Alternative Splicing GalleryENSG00000160767
Gene ExpressionFAM189B [ NCBI-GEO ]   FAM189B [ EBI - ARRAY_EXPRESS ]   FAM189B [ SEEK ]   FAM189B [ MEM ]
Gene Expression Viewer (FireBrowse)FAM189B [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10712
GTEX Portal (Tissue expression)FAM189B
Protein : pattern, domain, 3D structure
UniProt/SwissProtP81408   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP81408  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP81408
Splice isoforms : SwissVarP81408
PhosPhoSitePlusP81408
Domains : Interpro (EBI)CD20-like    FAM189   
Domain families : Pfam (Sanger)CD20 (PF04103)   
Domain families : Pfam (NCBI)pfam04103   
Conserved Domain (NCBI)FAM189B
DMDM Disease mutations10712
Blocks (Seattle)FAM189B
SuperfamilyP81408
Human Protein AtlasENSG00000160767
Peptide AtlasP81408
HPRD08511
IPIIPI00514706   IPI00386600   IPI00647475   IPI00383800   IPI00062858   IPI00646449   IPI00059407   IPI00966322   
Protein Interaction databases
DIP (DOE-UCLA)P81408
IntAct (EBI)P81408
FunCoupENSG00000160767
BioGRIDFAM189B
STRING (EMBL)FAM189B
ZODIACFAM189B
Ontologies - Pathways
QuickGOP81408
Ontology : AmiGOprotein binding  biological_process  integral component of membrane  WW domain binding  
Ontology : EGO-EBIprotein binding  biological_process  integral component of membrane  WW domain binding  
NDEx NetworkFAM189B
Atlas of Cancer Signalling NetworkFAM189B
Wikipedia pathwaysFAM189B
Orthology - Evolution
OrthoDB10712
GeneTree (enSembl)ENSG00000160767
Phylogenetic Trees/Animal Genes : TreeFamFAM189B
HOVERGENP81408
HOGENOMP81408
Homologs : HomoloGeneFAM189B
Homology/Alignments : Family Browser (UCSC)FAM189B
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerFAM189B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)FAM189B
dbVarFAM189B
ClinVarFAM189B
1000_GenomesFAM189B 
Exome Variant ServerFAM189B
ExAC (Exome Aggregation Consortium)FAM189B (select the gene name)
Genetic variants : HAPMAP10712
Genomic Variants (DGV)FAM189B [DGVbeta]
DECIPHERFAM189B [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisFAM189B 
Mutations
ICGC Data PortalFAM189B 
TCGA Data PortalFAM189B 
Broad Tumor PortalFAM189B
OASIS PortalFAM189B [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICFAM189B  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDFAM189B
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch FAM189B
DgiDB (Drug Gene Interaction Database)FAM189B
DoCM (Curated mutations)FAM189B (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)FAM189B (select a term)
intoGenFAM189B
Cancer3DFAM189B(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenFAM189B
Genetic Testing Registry FAM189B
NextProtP81408 [Medical]
TSGene10712
GENETestsFAM189B
Huge Navigator FAM189B [HugePedia]
snp3D : Map Gene to Disease10712
BioCentury BCIQFAM189B
ClinGenFAM189B
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD10712
Chemical/Pharm GKB GenePA25608
Clinical trialFAM189B
Miscellaneous
canSAR (ICR)FAM189B (select the gene name)
Probes
Litterature
PubMed12 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineFAM189B
EVEXFAM189B
GoPubMedFAM189B
iHOPFAM189B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri May 19 12:15:22 CEST 2017

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