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FAM21C (family with sequence similarity 21, member C)

Identity

Alias_namesfamily with sequence similarity 21, member C
Alias_symbol (synonym)Em:AC012044.3
KIAA0592
Other aliasFAM21A
VPEF
HGNC (Hugo) FAM21C
LocusID (NCBI) 253725
Atlas_Id 63149
Location 10q11.22  [Link to chromosome band 10q11]
Location_base_pair Starts at 46222648 and ends at 46288412 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
cytochrome_b () / FAM21C (10q11.22)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)FAM21C   23414
Cards
Entrez_Gene (NCBI)FAM21C  253725  family with sequence similarity 21, member C
AliasesFAM21A; VPEF
GeneCards (Weizmann)FAM21C
Ensembl hg19 (Hinxton)ENSG00000172661 [Gene_View]  chr10:46222648-46288412 [Contig_View]  FAM21C [Vega]
Ensembl hg38 (Hinxton)ENSG00000172661 [Gene_View]  chr10:46222648-46288412 [Contig_View]  FAM21C [Vega]
ICGC DataPortalENSG00000172661
TCGA cBioPortalFAM21C
AceView (NCBI)FAM21C
Genatlas (Paris)FAM21C
WikiGenes253725
SOURCE (Princeton)FAM21C
Genetics Home Reference (NIH)FAM21C
Genomic and cartography
GoldenPath hg19 (UCSC)FAM21C  -     chr10:46222648-46288412 +  10q11.22   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)FAM21C  -     10q11.22   [Description]    (hg38-Dec_2013)
EnsemblFAM21C - 10q11.22 [CytoView hg19]  FAM21C - 10q11.22 [CytoView hg38]
Mapping of homologs : NCBIFAM21C [Mapview hg19]  FAM21C [Mapview hg38]
OMIM613631   
Gene and transcription
Genbank (Entrez)AB011164 AI356516 AK001545 AK291430 AK293929
RefSeq transcript (Entrez)NM_001169106 NM_001169107 NM_015262
RefSeq genomic (Entrez)NC_000010 NC_018921 NT_030059 NW_004929371
Consensus coding sequences : CCDS (NCBI)FAM21C
Cluster EST : UnigeneHs.449662 [ NCBI ]
CGAP (NCI)Hs.449662
Alternative Splicing GalleryENSG00000172661
Gene ExpressionFAM21C [ NCBI-GEO ]   FAM21C [ EBI - ARRAY_EXPRESS ]   FAM21C [ SEEK ]   FAM21C [ MEM ]
Gene Expression Viewer (FireBrowse)FAM21C [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)253725
GTEX Portal (Tissue expression)FAM21C
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y4E1   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y4E1  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y4E1
Splice isoforms : SwissVarQ9Y4E1
PhosPhoSitePlusQ9Y4E1
Domains : Interpro (EBI)FAM21    FAM21/CAPZIP   
Domain families : Pfam (Sanger)CAP-ZIP_m (PF15255)   
Domain families : Pfam (NCBI)pfam15255   
Conserved Domain (NCBI)FAM21C
DMDM Disease mutations253725
Blocks (Seattle)FAM21C
SuperfamilyQ9Y4E1
Human Protein AtlasENSG00000172661
Peptide AtlasQ9Y4E1
HPRD11094
IPIIPI00514705   IPI00456853   IPI00556261   IPI00954966   IPI01011204   IPI01011198   IPI00954891   IPI00966110   IPI00871172   
Protein Interaction databases
DIP (DOE-UCLA)Q9Y4E1
IntAct (EBI)Q9Y4E1
FunCoupENSG00000172661
BioGRIDFAM21C
STRING (EMBL)FAM21C
ZODIACFAM21C
Ontologies - Pathways
QuickGOQ9Y4E1
Ontology : AmiGOprotein binding  phosphatidylinositol-4,5-bisphosphate binding  phosphatidylinositol-3,4,5-trisphosphate binding  endosome  early endosome  plasma membrane  phosphatidylinositol-5-phosphate binding  protein transport  retromer complex  early endosome membrane  phosphatidylinositol-3-phosphate binding  retrograde transport, endosome to Golgi  phosphatidylinositol-3,4-bisphosphate binding  phosphatidylinositol-4-phosphate binding  WASH complex  phosphatidylinositol-3,5-bisphosphate binding  regulation of substrate adhesion-dependent cell spreading  retrograde transport, endosome to plasma membrane  negative regulation of barbed-end actin filament capping  
Ontology : EGO-EBIprotein binding  phosphatidylinositol-4,5-bisphosphate binding  phosphatidylinositol-3,4,5-trisphosphate binding  endosome  early endosome  plasma membrane  phosphatidylinositol-5-phosphate binding  protein transport  retromer complex  early endosome membrane  phosphatidylinositol-3-phosphate binding  retrograde transport, endosome to Golgi  phosphatidylinositol-3,4-bisphosphate binding  phosphatidylinositol-4-phosphate binding  WASH complex  phosphatidylinositol-3,5-bisphosphate binding  regulation of substrate adhesion-dependent cell spreading  retrograde transport, endosome to plasma membrane  negative regulation of barbed-end actin filament capping  
NDEx NetworkFAM21C
Atlas of Cancer Signalling NetworkFAM21C
Wikipedia pathwaysFAM21C
Orthology - Evolution
OrthoDB253725
GeneTree (enSembl)ENSG00000172661
Phylogenetic Trees/Animal Genes : TreeFamFAM21C
HOVERGENQ9Y4E1
HOGENOMQ9Y4E1
Homologs : HomoloGeneFAM21C
Homology/Alignments : Family Browser (UCSC)FAM21C
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerFAM21C [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)FAM21C
dbVarFAM21C
ClinVarFAM21C
1000_GenomesFAM21C 
Exome Variant ServerFAM21C
ExAC (Exome Aggregation Consortium)FAM21C (select the gene name)
Genetic variants : HAPMAP253725
Genomic Variants (DGV)FAM21C [DGVbeta]
DECIPHER (Syndromes)10:46222648-46288412  ENSG00000172661
CONAN: Copy Number AnalysisFAM21C 
Mutations
ICGC Data PortalFAM21C 
TCGA Data PortalFAM21C 
Broad Tumor PortalFAM21C
OASIS PortalFAM21C [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICFAM21C  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDFAM21C
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch FAM21C
DgiDB (Drug Gene Interaction Database)FAM21C
DoCM (Curated mutations)FAM21C (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)FAM21C (select a term)
intoGenFAM21C
Cancer3DFAM21C(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM613631   
Orphanet
MedgenFAM21C
Genetic Testing Registry FAM21C
NextProtQ9Y4E1 [Medical]
TSGene253725
GENETestsFAM21C
Huge Navigator FAM21C [HugePedia]
snp3D : Map Gene to Disease253725
BioCentury BCIQFAM21C
ClinGenFAM21C
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD253725
Chemical/Pharm GKB GenePA128394768
Clinical trialFAM21C
Miscellaneous
canSAR (ICR)FAM21C (select the gene name)
Probes
Litterature
PubMed29 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineFAM21C
EVEXFAM21C
GoPubMedFAM21C
iHOPFAM21C
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 12:03:57 CET 2017

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