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FAM3B (family with sequence similarity 3 member B)

Identity

Alias_namesC21orf11
chromosome 21 open reading frame 11
family with sequence similarity 3, member B
Alias_symbol (synonym)D21M16SJHU19e
PRED44
2-21
ORF9
C21orf76
PANDER
Other alias
HGNC (Hugo) FAM3B
LocusID (NCBI) 54097
Atlas_Id 53174
Location 21q22.3  [Link to chromosome band 21q22]
Location_base_pair Starts at 41316734 and ends at 41357727 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
GLI3 (7p14.1) / FAM3B (21q22.3)MORC3 (21q22.12) / FAM3B (21q22.3)MORC3 21q22.12 / FAM3B 21q22.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)FAM3B   1253
Cards
Entrez_Gene (NCBI)FAM3B  54097  family with sequence similarity 3 member B
Aliases2-21; C21orf11; C21orf76; ORF9; 
PANDER; PRED44
GeneCards (Weizmann)FAM3B
Ensembl hg19 (Hinxton)ENSG00000183844 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000183844 [Gene_View]  chr21:41316734-41357727 [Contig_View]  FAM3B [Vega]
ICGC DataPortalENSG00000183844
TCGA cBioPortalFAM3B
AceView (NCBI)FAM3B
Genatlas (Paris)FAM3B
WikiGenes54097
SOURCE (Princeton)FAM3B
Genetics Home Reference (NIH)FAM3B
Genomic and cartography
GoldenPath hg38 (UCSC)FAM3B  -     chr21:41316734-41357727 +  21q22.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)FAM3B  -     21q22.3   [Description]    (hg19-Feb_2009)
EnsemblFAM3B - 21q22.3 [CytoView hg19]  FAM3B - 21q22.3 [CytoView hg38]
Mapping of homologs : NCBIFAM3B [Mapview hg19]  FAM3B [Mapview hg38]
OMIM608617   
Gene and transcription
Genbank (Entrez)AF375989 AF494379 AJ409094 AK125528 AK302095
RefSeq transcript (Entrez)NM_058186 NM_206964
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)FAM3B
Cluster EST : UnigeneHs.670704 [ NCBI ]
CGAP (NCI)Hs.670704
Alternative Splicing GalleryENSG00000183844
Gene ExpressionFAM3B [ NCBI-GEO ]   FAM3B [ EBI - ARRAY_EXPRESS ]   FAM3B [ SEEK ]   FAM3B [ MEM ]
Gene Expression Viewer (FireBrowse)FAM3B [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)54097
GTEX Portal (Tissue expression)FAM3B
Protein : pattern, domain, 3D structure
UniProt/SwissProtP58499   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP58499  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP58499
Splice isoforms : SwissVarP58499
PhosPhoSitePlusP58499
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)FAM3B
DMDM Disease mutations54097
Blocks (Seattle)FAM3B
SuperfamilyP58499
Human Protein AtlasENSG00000183844
Peptide AtlasP58499
HPRD10552
IPIIPI00067738   IPI00219788   IPI00219789   IPI00790820   
Protein Interaction databases
DIP (DOE-UCLA)P58499
IntAct (EBI)P58499
FunCoupENSG00000183844
BioGRIDFAM3B
STRING (EMBL)FAM3B
ZODIACFAM3B
Ontologies - Pathways
QuickGOP58499
Ontology : AmiGOcytokine activity  extracellular region  extracellular space  apoptotic process  insulin secretion  extracellular exosome  
Ontology : EGO-EBIcytokine activity  extracellular region  extracellular space  apoptotic process  insulin secretion  extracellular exosome  
NDEx NetworkFAM3B
Atlas of Cancer Signalling NetworkFAM3B
Wikipedia pathwaysFAM3B
Orthology - Evolution
OrthoDB54097
GeneTree (enSembl)ENSG00000183844
Phylogenetic Trees/Animal Genes : TreeFamFAM3B
HOVERGENP58499
HOGENOMP58499
Homologs : HomoloGeneFAM3B
Homology/Alignments : Family Browser (UCSC)FAM3B
Gene fusions - Rearrangements
Fusion : MitelmanGLI3/FAM3B [7p14.1/21q22.3]  [t(7;21)(p14;q22)]  
Fusion : MitelmanMORC3/FAM3B [21q22.12/21q22.3]  [t(21;21)(q22;q22)]  
Fusion: TCGAMORC3 21q22.12 FAM3B 21q22.3 LUSC
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerFAM3B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)FAM3B
dbVarFAM3B
ClinVarFAM3B
1000_GenomesFAM3B 
Exome Variant ServerFAM3B
ExAC (Exome Aggregation Consortium)FAM3B (select the gene name)
Genetic variants : HAPMAP54097
Genomic Variants (DGV)FAM3B [DGVbeta]
DECIPHERFAM3B [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisFAM3B 
Mutations
ICGC Data PortalFAM3B 
TCGA Data PortalFAM3B 
Broad Tumor PortalFAM3B
OASIS PortalFAM3B [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICFAM3B  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDFAM3B
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch FAM3B
DgiDB (Drug Gene Interaction Database)FAM3B
DoCM (Curated mutations)FAM3B (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)FAM3B (select a term)
intoGenFAM3B
Cancer3DFAM3B(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM608617   
Orphanet
MedgenFAM3B
Genetic Testing Registry FAM3B
NextProtP58499 [Medical]
TSGene54097
GENETestsFAM3B
Target ValidationFAM3B
Huge Navigator FAM3B [HugePedia]
snp3D : Map Gene to Disease54097
BioCentury BCIQFAM3B
ClinGenFAM3B
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD54097
Chemical/Pharm GKB GenePA27979
Clinical trialFAM3B
Miscellaneous
canSAR (ICR)FAM3B (select the gene name)
Probes
Litterature
PubMed23 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineFAM3B
EVEXFAM3B
GoPubMedFAM3B
iHOPFAM3B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Aug 1 17:00:53 CEST 2017

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