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FAM46A (family with sequence similarity 46 member A)

Identity

Alias_namesC6orf37
chromosome 6 open reading frame 37
family with sequence similarity 46, member A
Alias_symbol (synonym)FLJ20037
Other aliasXTP11
HGNC (Hugo) FAM46A
LocusID (NCBI) 55603
Atlas_Id 45730
Location 6q14.1  [Link to chromosome band 6q14]
Location_base_pair Starts at 81745730 and ends at 81752711 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
FAM134A (2q35) / FAM46A (6q14.1)FAM46A (6q14.1) / EPAS1 (2p21)FAM46A (6q14.1) / MED15 (22q11.21)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)FAM46A   18345
Cards
Entrez_Gene (NCBI)FAM46A  55603  family with sequence similarity 46 member A
AliasesC6orf37; XTP11
GeneCards (Weizmann)FAM46A
Ensembl hg19 (Hinxton)ENSG00000112773 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000112773 [Gene_View]  chr6:81745730-81752711 [Contig_View]  FAM46A [Vega]
ICGC DataPortalENSG00000112773
TCGA cBioPortalFAM46A
AceView (NCBI)FAM46A
Genatlas (Paris)FAM46A
WikiGenes55603
SOURCE (Princeton)FAM46A
Genetics Home Reference (NIH)FAM46A
Genomic and cartography
GoldenPath hg38 (UCSC)FAM46A  -     chr6:81745730-81752711 -  6q14.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)FAM46A  -     6q14.1   [Description]    (hg19-Feb_2009)
EnsemblFAM46A - 6q14.1 [CytoView hg19]  FAM46A - 6q14.1 [CytoView hg38]
Mapping of homologs : NCBIFAM46A [Mapview hg19]  FAM46A [Mapview hg38]
OMIM611357   
Gene and transcription
Genbank (Entrez)AF350451 AI131001 AJ420583 AJ420591 AJ420592
RefSeq transcript (Entrez)NM_017633
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)FAM46A
Cluster EST : UnigeneHs.10784 [ NCBI ]
CGAP (NCI)Hs.10784
Alternative Splicing GalleryENSG00000112773
Gene ExpressionFAM46A [ NCBI-GEO ]   FAM46A [ EBI - ARRAY_EXPRESS ]   FAM46A [ SEEK ]   FAM46A [ MEM ]
Gene Expression Viewer (FireBrowse)FAM46A [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)55603
GTEX Portal (Tissue expression)FAM46A
Human Protein AtlasENSG00000112773-FAM46A [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96IP4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96IP4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96IP4
Splice isoforms : SwissVarQ96IP4
PhosPhoSitePlusQ96IP4
Domains : Interpro (EBI)DUF1693   
Domain families : Pfam (Sanger)NTP_transf_7 (PF07984)   
Domain families : Pfam (NCBI)pfam07984   
Domain families : Smart (EMBL)DUF1693 (SM01153)  
Conserved Domain (NCBI)FAM46A
DMDM Disease mutations55603
Blocks (Seattle)FAM46A
SuperfamilyQ96IP4
Human Protein Atlas [tissue]ENSG00000112773-FAM46A [tissue]
Peptide AtlasQ96IP4
HPRD13311
IPIIPI00640117   IPI00410700   IPI00643049   IPI00643508   IPI00647115   
Protein Interaction databases
DIP (DOE-UCLA)Q96IP4
IntAct (EBI)Q96IP4
FunCoupENSG00000112773
BioGRIDFAM46A
STRING (EMBL)FAM46A
ZODIACFAM46A
Ontologies - Pathways
QuickGOQ96IP4
Ontology : AmiGORNA binding  protein binding  regulation of gene expression  regulation of blood coagulation  
Ontology : EGO-EBIRNA binding  protein binding  regulation of gene expression  regulation of blood coagulation  
NDEx NetworkFAM46A
Atlas of Cancer Signalling NetworkFAM46A
Wikipedia pathwaysFAM46A
Orthology - Evolution
OrthoDB55603
GeneTree (enSembl)ENSG00000112773
Phylogenetic Trees/Animal Genes : TreeFamFAM46A
HOVERGENQ96IP4
HOGENOMQ96IP4
Homologs : HomoloGeneFAM46A
Homology/Alignments : Family Browser (UCSC)FAM46A
Gene fusions - Rearrangements
Fusion : QuiverFAM46A
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerFAM46A [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)FAM46A
dbVarFAM46A
ClinVarFAM46A
1000_GenomesFAM46A 
Exome Variant ServerFAM46A
ExAC (Exome Aggregation Consortium)ENSG00000112773
GNOMAD BrowserENSG00000112773
Genetic variants : HAPMAP55603
Genomic Variants (DGV)FAM46A [DGVbeta]
DECIPHERFAM46A [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisFAM46A 
Mutations
ICGC Data PortalFAM46A 
TCGA Data PortalFAM46A 
Broad Tumor PortalFAM46A
OASIS PortalFAM46A [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICFAM46A  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDFAM46A
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch FAM46A
DgiDB (Drug Gene Interaction Database)FAM46A
DoCM (Curated mutations)FAM46A (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)FAM46A (select a term)
intoGenFAM46A
Cancer3DFAM46A(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611357   
Orphanet
DisGeNETFAM46A
MedgenFAM46A
Genetic Testing Registry FAM46A
NextProtQ96IP4 [Medical]
TSGene55603
GENETestsFAM46A
Target ValidationFAM46A
Huge Navigator FAM46A [HugePedia]
snp3D : Map Gene to Disease55603
BioCentury BCIQFAM46A
ClinGenFAM46A
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD55603
Chemical/Pharm GKB GenePA38531
Clinical trialFAM46A
Miscellaneous
canSAR (ICR)FAM46A (select the gene name)
Probes
Litterature
PubMed29 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineFAM46A
EVEXFAM46A
GoPubMedFAM46A
iHOPFAM46A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri Jan 5 11:52:10 CET 2018

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