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FAM50B (family with sequence similarity 50 member B)

Identity

Alias_namesfamily with sequence similarity 50
Alias_symbol (synonym)D6S2654E
X5L
Other alias
HGNC (Hugo) FAM50B
LocusID (NCBI) 26240
Atlas_Id 54309
Location 6p25.2  [Link to chromosome band 6p25]
Location_base_pair Starts at 3849366 and ends at 3851320 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
FAM50B (6p25.2) / PPP1R3G (6p25.1)PPP1R3G (6p25.1) / FAM50B (6p25.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  Lung: Translocations in Squamous Cell Carcinoma


External links

Nomenclature
HGNC (Hugo)FAM50B   18789
LRG (Locus Reference Genomic)LRG_1062
Cards
Entrez_Gene (NCBI)FAM50B  26240  family with sequence similarity 50 member B
AliasesD6S2654E; X5L
GeneCards (Weizmann)FAM50B
Ensembl hg19 (Hinxton)ENSG00000145945 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000145945 [Gene_View]  chr6:3849366-3851320 [Contig_View]  FAM50B [Vega]
ICGC DataPortalENSG00000145945
TCGA cBioPortalFAM50B
AceView (NCBI)FAM50B
Genatlas (Paris)FAM50B
WikiGenes26240
SOURCE (Princeton)FAM50B
Genetics Home Reference (NIH)FAM50B
Genomic and cartography
GoldenPath hg38 (UCSC)FAM50B  -     chr6:3849366-3851320 +  6p25.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)FAM50B  -     6p25.2   [Description]    (hg19-Feb_2009)
EnsemblFAM50B - 6p25.2 [CytoView hg19]  FAM50B - 6p25.2 [CytoView hg38]
Mapping of homologs : NCBIFAM50B [Mapview hg19]  FAM50B [Mapview hg38]
OMIM614686   
Gene and transcription
Genbank (Entrez)BC001261 BI488606 DB566944 HQ447810 Y18503
RefSeq transcript (Entrez)NM_012135
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)FAM50B
Cluster EST : UnigeneHs.140944 [ NCBI ]
CGAP (NCI)Hs.140944
Alternative Splicing GalleryENSG00000145945
Gene ExpressionFAM50B [ NCBI-GEO ]   FAM50B [ EBI - ARRAY_EXPRESS ]   FAM50B [ SEEK ]   FAM50B [ MEM ]
Gene Expression Viewer (FireBrowse)FAM50B [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)26240
GTEX Portal (Tissue expression)FAM50B
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y247   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y247  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y247
Splice isoforms : SwissVarQ9Y247
PhosPhoSitePlusQ9Y247
Domains : Interpro (EBI)XAP5   
Domain families : Pfam (Sanger)XAP5 (PF04921)   
Domain families : Pfam (NCBI)pfam04921   
Conserved Domain (NCBI)FAM50B
DMDM Disease mutations26240
Blocks (Seattle)FAM50B
SuperfamilyQ9Y247
Human Protein AtlasENSG00000145945
Peptide AtlasQ9Y247
HPRD16883
IPIIPI00015912   
Protein Interaction databases
DIP (DOE-UCLA)Q9Y247
IntAct (EBI)Q9Y247
FunCoupENSG00000145945
BioGRIDFAM50B
STRING (EMBL)FAM50B
ZODIACFAM50B
Ontologies - Pathways
QuickGOQ9Y247
Ontology : AmiGOprotein binding  nucleoplasm  intercellular bridge  
Ontology : EGO-EBIprotein binding  nucleoplasm  intercellular bridge  
NDEx NetworkFAM50B
Atlas of Cancer Signalling NetworkFAM50B
Wikipedia pathwaysFAM50B
Orthology - Evolution
OrthoDB26240
GeneTree (enSembl)ENSG00000145945
Phylogenetic Trees/Animal Genes : TreeFamFAM50B
HOVERGENQ9Y247
HOGENOMQ9Y247
Homologs : HomoloGeneFAM50B
Homology/Alignments : Family Browser (UCSC)FAM50B
Gene fusions - Rearrangements
Fusion : MitelmanFAM50B/PPP1R3G [6p25.2/6p25.1]  
Fusion : MitelmanPPP1R3G/FAM50B [6p25.1/6p25.2]  [t(6;6)(p25;p25)]  
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerFAM50B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)FAM50B
dbVarFAM50B
ClinVarFAM50B
1000_GenomesFAM50B 
Exome Variant ServerFAM50B
ExAC (Exome Aggregation Consortium)FAM50B (select the gene name)
Genetic variants : HAPMAP26240
Genomic Variants (DGV)FAM50B [DGVbeta]
DECIPHERFAM50B [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisFAM50B 
Mutations
ICGC Data PortalFAM50B 
TCGA Data PortalFAM50B 
Broad Tumor PortalFAM50B
OASIS PortalFAM50B [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICFAM50B  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDFAM50B
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch FAM50B
DgiDB (Drug Gene Interaction Database)FAM50B
DoCM (Curated mutations)FAM50B (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)FAM50B (select a term)
intoGenFAM50B
Cancer3DFAM50B(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM614686   
Orphanet
MedgenFAM50B
Genetic Testing Registry FAM50B
NextProtQ9Y247 [Medical]
TSGene26240
GENETestsFAM50B
Target ValidationFAM50B
Huge Navigator FAM50B [HugePedia]
snp3D : Map Gene to Disease26240
BioCentury BCIQFAM50B
ClinGenFAM50B
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD26240
Chemical/Pharm GKB GenePA134912073
Clinical trialFAM50B
Miscellaneous
canSAR (ICR)FAM50B (select the gene name)
Probes
Litterature
PubMed16 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineFAM50B
EVEXFAM50B
GoPubMedFAM50B
iHOPFAM50B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 19:07:47 CEST 2017

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