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FAM58A (family with sequence similarity 58 member A)

Identity

Alias_namesfamily with sequence similarity 58, member A
Alias_symbol (synonym)MGC29729
FLJ21610
Other aliasCCNQ
STAR
HGNC (Hugo) FAM58A
LocusID (NCBI) 92002
Atlas_Id 63213
Location Xq28  [Link to chromosome band Xq28]
Location_base_pair Starts at 153587925 and ends at 153599177 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)FAM58A   28434
Cards
Entrez_Gene (NCBI)FAM58A  92002  family with sequence similarity 58 member A
AliasesCCNQ; STAR
GeneCards (Weizmann)FAM58A
Ensembl hg19 (Hinxton)ENSG00000262919 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000262919 [Gene_View]  chrX:153587925-153599177 [Contig_View]  FAM58A [Vega]
ICGC DataPortalENSG00000262919
TCGA cBioPortalFAM58A
AceView (NCBI)FAM58A
Genatlas (Paris)FAM58A
WikiGenes92002
SOURCE (Princeton)FAM58A
Genetics Home Reference (NIH)FAM58A
Genomic and cartography
GoldenPath hg38 (UCSC)FAM58A  -     chrX:153587925-153599177 -  Xq28   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)FAM58A  -     Xq28   [Description]    (hg19-Feb_2009)
EnsemblFAM58A - Xq28 [CytoView hg19]  FAM58A - Xq28 [CytoView hg38]
Mapping of homologs : NCBIFAM58A [Mapview hg19]  FAM58A [Mapview hg38]
OMIM300707   300708   
Gene and transcription
Genbank (Entrez)AL549300 AM393666 AY445048 BC001909 BC007232
RefSeq transcript (Entrez)NM_001130997 NM_152274
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)FAM58A
Cluster EST : UnigeneHs.496943 [ NCBI ]
CGAP (NCI)Hs.496943
Alternative Splicing GalleryENSG00000262919
Gene ExpressionFAM58A [ NCBI-GEO ]   FAM58A [ EBI - ARRAY_EXPRESS ]   FAM58A [ SEEK ]   FAM58A [ MEM ]
Gene Expression Viewer (FireBrowse)FAM58A [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)92002
GTEX Portal (Tissue expression)FAM58A
Human Protein AtlasENSG00000262919-FAM58A [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8N1B3   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8N1B3  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8N1B3
Splice isoforms : SwissVarQ8N1B3
PhosPhoSitePlusQ8N1B3
Domains : Interpro (EBI)Cyclin-like    Cyclin-rel_FAM58    Cyclin_N   
Domain families : Pfam (Sanger)Cyclin_N (PF00134)   
Domain families : Pfam (NCBI)pfam00134   
Domain families : Smart (EMBL)CYCLIN (SM00385)  
Conserved Domain (NCBI)FAM58A
DMDM Disease mutations92002
Blocks (Seattle)FAM58A
SuperfamilyQ8N1B3
Human Protein Atlas [tissue]ENSG00000262919-FAM58A [tissue]
Peptide AtlasQ8N1B3
HPRD06645
IPIIPI00643557   IPI00647327   IPI00642914   IPI00641042   IPI00646678   IPI00639977   IPI00395371   
Protein Interaction databases
DIP (DOE-UCLA)Q8N1B3
IntAct (EBI)Q8N1B3
FunCoupENSG00000262919
BioGRIDFAM58A
STRING (EMBL)FAM58A
ZODIACFAM58A
Ontologies - Pathways
QuickGOQ8N1B3
Ontology : AmiGOcyclin-dependent protein kinase holoenzyme complex  protein binding  nucleus  cyclin-dependent protein serine/threonine kinase regulator activity  protein kinase activator activity  activation of protein kinase activity  positive regulation of MAPK cascade  positive regulation of cyclin-dependent protein serine/threonine kinase activity  positive regulation of transcription from RNA polymerase II promoter  positive regulation of phosphorylation of RNA polymerase II C-terminal domain  
Ontology : EGO-EBIcyclin-dependent protein kinase holoenzyme complex  protein binding  nucleus  cyclin-dependent protein serine/threonine kinase regulator activity  protein kinase activator activity  activation of protein kinase activity  positive regulation of MAPK cascade  positive regulation of cyclin-dependent protein serine/threonine kinase activity  positive regulation of transcription from RNA polymerase II promoter  positive regulation of phosphorylation of RNA polymerase II C-terminal domain  
NDEx NetworkFAM58A
Atlas of Cancer Signalling NetworkFAM58A
Wikipedia pathwaysFAM58A
Orthology - Evolution
OrthoDB92002
GeneTree (enSembl)ENSG00000262919
Phylogenetic Trees/Animal Genes : TreeFamFAM58A
HOVERGENQ8N1B3
HOGENOMQ8N1B3
Homologs : HomoloGeneFAM58A
Homology/Alignments : Family Browser (UCSC)FAM58A
Gene fusions - Rearrangements
Tumor Fusion PortalFAM58A
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerFAM58A [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)FAM58A
dbVarFAM58A
ClinVarFAM58A
1000_GenomesFAM58A 
Exome Variant ServerFAM58A
ExAC (Exome Aggregation Consortium)ENSG00000262919
GNOMAD BrowserENSG00000262919
Genetic variants : HAPMAP92002
Genomic Variants (DGV)FAM58A [DGVbeta]
DECIPHERFAM58A [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisFAM58A 
Mutations
ICGC Data PortalFAM58A 
TCGA Data PortalFAM58A 
Broad Tumor PortalFAM58A
OASIS PortalFAM58A [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICFAM58A  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDFAM58A
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch FAM58A
DgiDB (Drug Gene Interaction Database)FAM58A
DoCM (Curated mutations)FAM58A (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)FAM58A (select a term)
intoGenFAM58A
Cancer3DFAM58A(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM300707    300708   
Orphanet17006   
DisGeNETFAM58A
MedgenFAM58A
Genetic Testing Registry FAM58A
NextProtQ8N1B3 [Medical]
TSGene92002
GENETestsFAM58A
Target ValidationFAM58A
Huge Navigator FAM58A [HugePedia]
snp3D : Map Gene to Disease92002
BioCentury BCIQFAM58A
ClinGenFAM58A
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD92002
Chemical/Pharm GKB GenePA142671863
Clinical trialFAM58A
Miscellaneous
canSAR (ICR)FAM58A (select the gene name)
Probes
Litterature
PubMed12 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineFAM58A
EVEXFAM58A
GoPubMedFAM58A
iHOPFAM58A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 21 13:45:23 CET 2017

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