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FAM83B (family with sequence similarity 83 member B)

Identity

Alias_namesC6orf143
chromosome 6 open reading frame 143
family with sequence similarity 83, member B
Alias_symbol (synonym)FLJ30642
Other alias
HGNC (Hugo) FAM83B
LocusID (NCBI) 222584
Atlas_Id 53113
Location 6p12.1  [Link to chromosome band 6p12]
Location_base_pair Starts at 54846771 and ends at 54945099 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
FAM83B (6p12.1) / HTR1E (6q14.3)NUMA1 (11q13.4) / FAM83B (6p12.1)NUMA1 11q13.4 / FAM83B 6p12.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 3 ]
  Lung: Translocations in Squamous Cell Carcinoma
t(6;6)(p12;q14) FAM83B/HTR1E
t(6;11)(p12;q13) NUMA1/FAM83B


External links

Nomenclature
HGNC (Hugo)FAM83B   21357
Cards
Entrez_Gene (NCBI)FAM83B  222584  family with sequence similarity 83 member B
AliasesC6orf143
GeneCards (Weizmann)FAM83B
Ensembl hg19 (Hinxton)ENSG00000168143 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000168143 [Gene_View]  ENSG00000168143 [Sequence]  chr6:54846771-54945099 [Contig_View]  FAM83B [Vega]
ICGC DataPortalENSG00000168143
TCGA cBioPortalFAM83B
AceView (NCBI)FAM83B
Genatlas (Paris)FAM83B
WikiGenes222584
SOURCE (Princeton)FAM83B
Genetics Home Reference (NIH)FAM83B
Genomic and cartography
GoldenPath hg38 (UCSC)FAM83B  -     chr6:54846771-54945099 +  6p12.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)FAM83B  -     6p12.1   [Description]    (hg19-Feb_2009)
EnsemblFAM83B - 6p12.1 [CytoView hg19]  FAM83B - 6p12.1 [CytoView hg38]
Mapping of homologs : NCBIFAM83B [Mapview hg19]  FAM83B [Mapview hg38]
Gene and transcription
Genbank (Entrez)AK024927 AK055204 BC101628 BC112275
RefSeq transcript (Entrez)NM_001010872
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)FAM83B
Cluster EST : UnigeneHs.152423 [ NCBI ]
CGAP (NCI)Hs.152423
Alternative Splicing GalleryENSG00000168143
Gene ExpressionFAM83B [ NCBI-GEO ]   FAM83B [ EBI - ARRAY_EXPRESS ]   FAM83B [ SEEK ]   FAM83B [ MEM ]
Gene Expression Viewer (FireBrowse)FAM83B [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)222584
GTEX Portal (Tissue expression)FAM83B
Human Protein AtlasENSG00000168143-FAM83B [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ5T0W9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ5T0W9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ5T0W9
Splice isoforms : SwissVarQ5T0W9
PhosPhoSitePlusQ5T0W9
Domains : Interpro (EBI)FAM83   
Domain families : Pfam (Sanger)DUF1669 (PF07894)   
Domain families : Pfam (NCBI)pfam07894   
Conserved Domain (NCBI)FAM83B
DMDM Disease mutations222584
Blocks (Seattle)FAM83B
PDB (SRS)5LZK   
PDB (PDBSum)5LZK   
PDB (IMB)5LZK   
PDB (RSDB)5LZK   
Structural Biology KnowledgeBase5LZK   
SCOP (Structural Classification of Proteins)5LZK   
CATH (Classification of proteins structures)5LZK   
SuperfamilyQ5T0W9
Human Protein Atlas [tissue]ENSG00000168143-FAM83B [tissue]
Peptide AtlasQ5T0W9
HPRD10158
IPIIPI00304527   
Protein Interaction databases
DIP (DOE-UCLA)Q5T0W9
IntAct (EBI)Q5T0W9
FunCoupENSG00000168143
BioGRIDFAM83B
STRING (EMBL)FAM83B
ZODIACFAM83B
Ontologies - Pathways
QuickGOQ5T0W9
Ontology : AmiGOphospholipase D activity  epidermal growth factor receptor binding  cytoplasm  epidermal growth factor receptor signaling pathway  epidermal growth factor receptor signaling pathway  cell proliferation  membrane  protein kinase binding  protein kinase binding  phosphatidylinositol 3-kinase regulatory subunit binding  phosphatidylinositol 3-kinase catalytic subunit binding  
Ontology : EGO-EBIphospholipase D activity  epidermal growth factor receptor binding  cytoplasm  epidermal growth factor receptor signaling pathway  epidermal growth factor receptor signaling pathway  cell proliferation  membrane  protein kinase binding  protein kinase binding  phosphatidylinositol 3-kinase regulatory subunit binding  phosphatidylinositol 3-kinase catalytic subunit binding  
NDEx NetworkFAM83B
Atlas of Cancer Signalling NetworkFAM83B
Wikipedia pathwaysFAM83B
Orthology - Evolution
OrthoDB222584
GeneTree (enSembl)ENSG00000168143
Phylogenetic Trees/Animal Genes : TreeFamFAM83B
HOVERGENQ5T0W9
HOGENOMQ5T0W9
Homologs : HomoloGeneFAM83B
Homology/Alignments : Family Browser (UCSC)FAM83B
Gene fusions - Rearrangements
Fusion : MitelmanFAM83B/HTR1E [6p12.1/6q14.3]  
Fusion : MitelmanNUMA1/FAM83B [11q13.4/6p12.1]  [t(6;11)(p12;q13)]  
Fusion PortalNUMA1 11q13.4 FAM83B 6p12.1 BRCA
Fusion : QuiverFAM83B
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerFAM83B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)FAM83B
dbVarFAM83B
ClinVarFAM83B
1000_GenomesFAM83B 
Exome Variant ServerFAM83B
ExAC (Exome Aggregation Consortium)ENSG00000168143
GNOMAD BrowserENSG00000168143
Varsome BrowserFAM83B
Genetic variants : HAPMAP222584
Genomic Variants (DGV)FAM83B [DGVbeta]
DECIPHERFAM83B [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisFAM83B 
Mutations
ICGC Data PortalFAM83B 
TCGA Data PortalFAM83B 
Broad Tumor PortalFAM83B
OASIS PortalFAM83B [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICFAM83B  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDFAM83B
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch FAM83B
DgiDB (Drug Gene Interaction Database)FAM83B
DoCM (Curated mutations)FAM83B (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)FAM83B (select a term)
intoGenFAM83B
Cancer3DFAM83B(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETFAM83B
MedgenFAM83B
Genetic Testing Registry FAM83B
NextProtQ5T0W9 [Medical]
TSGene222584
GENETestsFAM83B
Target ValidationFAM83B
Huge Navigator FAM83B [HugePedia]
snp3D : Map Gene to Disease222584
BioCentury BCIQFAM83B
ClinGenFAM83B
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD222584
Chemical/Pharm GKB GenePA134987811
Clinical trialFAM83B
Miscellaneous
canSAR (ICR)FAM83B (select the gene name)
Probes
Litterature
PubMed20 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineFAM83B
EVEXFAM83B
GoPubMedFAM83B
iHOPFAM83B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 6 11:05:47 CET 2018

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