FAM83D (family with sequence similarity 83 member D)

2015-02-01  

Identity

HGNC
LOCATION
20q11.23
LOCUSID
ALIAS
C20orf129,CHICA,dJ616B8.3
FUSION GENES

Other Information

Locus ID:

NCBI: 81610
MIM: 618380
HGNC: 16122
Ensembl: ENSG00000101447

Variants:

dbSNP: 81610
ClinVar: 81610
TCGA: ENSG00000101447
COSMIC: FAM83D

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000101447ENST00000619304A0A087WXK8
ENSG00000101447ENST00000619850Q9H4H8

Expression (GTEx)

0
50
100
150
200

References

Pubmed IDYearTitleCitations
243441172013FAM83D promotes cell proliferation and motility by downregulating tumor suppressor gene FBXW7.28
184857062008The spindle protein CHICA mediates localization of the chromokinesin Kid to the mitotic spindle.26
261252292015Upregulation of FAM83D affects the proliferation and invasion of hepatocellular carcinoma.16
256466922015FAM83D activates the MEK/ERK signaling pathway and promotes cell proliferation in hepatocellular carcinoma.15
284075752017FAM83D knockdown regulates proliferation, migration and invasion of colorectal cancer through inhibiting FBXW7/Notch-1 signalling pathway.10
266526542016The Anchored Flexibility Model in LC8 Motif Recognition: Insights from the Chica Complex.9
277690482016FAM83D associates with high tumor recurrence after liver transplantation involving expansion of CD44+ carcinoma stem cells.9
266780352016Prognostic significance of FAM83D gene expression across human cancer types.8

Citation

Dessen P

FAM83D (family with sequence similarity 83 member D)

Atlas Genet Cytogenet Oncol Haematol. 2015-02-01

Online version: http://atlasgeneticsoncology.org/gene/55023/fam83d