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FAM89B (family with sequence similarity 89 member B)

Identity

Alias_namesfamily with sequence similarity 89, member B
Alias_symbol (synonym)MTVR1
LRAP25
Other aliasMTVR
HGNC (Hugo) FAM89B
LocusID (NCBI) 23625
Atlas_Id 43897
Location 11q13.1  [Link to chromosome band 11q13]
Location_base_pair Starts at 65572349 and ends at 65574198 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)FAM89B   16708
Cards
Entrez_Gene (NCBI)FAM89B  23625  family with sequence similarity 89 member B
AliasesLRAP25; MTVR; MTVR1
GeneCards (Weizmann)FAM89B
Ensembl hg19 (Hinxton)ENSG00000176973 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000176973 [Gene_View]  ENSG00000176973 [Sequence]  chr11:65572349-65574198 [Contig_View]  FAM89B [Vega]
ICGC DataPortalENSG00000176973
TCGA cBioPortalFAM89B
AceView (NCBI)FAM89B
Genatlas (Paris)FAM89B
WikiGenes23625
SOURCE (Princeton)FAM89B
Genetics Home Reference (NIH)FAM89B
Genomic and cartography
GoldenPath hg38 (UCSC)FAM89B  -     chr11:65572349-65574198 +  11q13.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)FAM89B  -     11q13.1   [Description]    (hg19-Feb_2009)
GoldenPathFAM89B - 11q13.1 [CytoView hg19]  FAM89B - 11q13.1 [CytoView hg38]
ImmunoBaseENSG00000176973
Mapping of homologs : NCBIFAM89B [Mapview hg19]  FAM89B [Mapview hg38]
OMIM616128   
Gene and transcription
Genbank (Entrez)AF052151 BC023991 BC032373 BE394215 BQ927525
RefSeq transcript (Entrez)NM_001098784 NM_001098785 NM_152832
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)FAM89B
Alternative Splicing GalleryENSG00000176973
Gene ExpressionFAM89B [ NCBI-GEO ]   FAM89B [ EBI - ARRAY_EXPRESS ]   FAM89B [ SEEK ]   FAM89B [ MEM ]
Gene Expression Viewer (FireBrowse)FAM89B [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)23625
GTEX Portal (Tissue expression)FAM89B
Human Protein AtlasENSG00000176973-FAM89B [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8N5H3   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8N5H3  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8N5H3
Splice isoforms : SwissVarQ8N5H3
PhosPhoSitePlusQ8N5H3
Domains : Interpro (EBI)LURA1/LRA25   
Domain families : Pfam (Sanger)LURAP (PF14854)   
Domain families : Pfam (NCBI)pfam14854   
Conserved Domain (NCBI)FAM89B
DMDM Disease mutations23625
Blocks (Seattle)FAM89B
SuperfamilyQ8N5H3
Human Protein Atlas [tissue]ENSG00000176973-FAM89B [tissue]
Peptide AtlasQ8N5H3
HPRD10100
IPIIPI00166855   IPI00448834   IPI00847432   
Protein Interaction databases
DIP (DOE-UCLA)Q8N5H3
IntAct (EBI)Q8N5H3
FunCoupENSG00000176973
BioGRIDFAM89B
STRING (EMBL)FAM89B
ZODIACFAM89B
Ontologies - Pathways
QuickGOQ8N5H3
Ontology : AmiGOtranscription corepressor binding  cytoplasm  establishment of cell polarity  lamellipodium  positive regulation of cell migration  negative regulation of transforming growth factor beta receptor signaling pathway  negative regulation of SMAD protein signal transduction  
Ontology : EGO-EBItranscription corepressor binding  cytoplasm  establishment of cell polarity  lamellipodium  positive regulation of cell migration  negative regulation of transforming growth factor beta receptor signaling pathway  negative regulation of SMAD protein signal transduction  
NDEx NetworkFAM89B
Atlas of Cancer Signalling NetworkFAM89B
Wikipedia pathwaysFAM89B
Orthology - Evolution
OrthoDB23625
GeneTree (enSembl)ENSG00000176973
Phylogenetic Trees/Animal Genes : TreeFamFAM89B
HOGENOMQ8N5H3
Homologs : HomoloGeneFAM89B
Homology/Alignments : Family Browser (UCSC)FAM89B
Gene fusions - Rearrangements
Fusion : QuiverFAM89B
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerFAM89B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)FAM89B
dbVarFAM89B
ClinVarFAM89B
1000_GenomesFAM89B 
Exome Variant ServerFAM89B
ExAC (Exome Aggregation Consortium)ENSG00000176973
GNOMAD BrowserENSG00000176973
Varsome BrowserFAM89B
Genetic variants : HAPMAP23625
Genomic Variants (DGV)FAM89B [DGVbeta]
DECIPHERFAM89B [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisFAM89B 
Mutations
ICGC Data PortalFAM89B 
TCGA Data PortalFAM89B 
Broad Tumor PortalFAM89B
OASIS PortalFAM89B [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICFAM89B  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DFAM89B
Mutations and Diseases : HGMDFAM89B
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch FAM89B
DgiDB (Drug Gene Interaction Database)FAM89B
DoCM (Curated mutations)FAM89B (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)FAM89B (select a term)
intoGenFAM89B
Cancer3DFAM89B(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM616128   
Orphanet
DisGeNETFAM89B
MedgenFAM89B
Genetic Testing Registry FAM89B
NextProtQ8N5H3 [Medical]
TSGene23625
GENETestsFAM89B
Target ValidationFAM89B
Huge Navigator FAM89B [HugePedia]
snp3D : Map Gene to Disease23625
BioCentury BCIQFAM89B
ClinGenFAM89B
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD23625
Chemical/Pharm GKB GenePA142671795
Clinical trialFAM89B
Miscellaneous
canSAR (ICR)FAM89B (select the gene name)
HarmonizomeFAM89B
DataMed IndexFAM89B
Probes
Litterature
PubMed11 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineFAM89B
EVEXFAM89B
GoPubMedFAM89B
iHOPFAM89B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Sun May 10 12:14:36 CEST 2020
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