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FAN1 (FANCD2 and FANCI associated nuclease 1)

Identity

Alias_namesKIAA1018
MTMR15
KIAA1018
myotubularin related protein 15
Other aliasKMIN
hFAN1
HGNC (Hugo) FAN1
LocusID (NCBI) 22909
Atlas_Id 51602
Location 15q13.3  [Link to chromosome band 15q13]
Location_base_pair Starts at 30903873 and ends at 30911788 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
FAN1 (15q13.2) / FAN1 (15q13.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)FAN1   29170
Cards
Entrez_Gene (NCBI)FAN1  22909  FANCD2 and FANCI associated nuclease 1
AliasesKIAA1018; KMIN; MTMR15; hFAN1
GeneCards (Weizmann)FAN1
Ensembl hg19 (Hinxton)ENSG00000198690 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000198690 [Gene_View]  chr15:30903873-30911788 [Contig_View]  FAN1 [Vega]
ICGC DataPortalENSG00000198690
TCGA cBioPortalFAN1
AceView (NCBI)FAN1
Genatlas (Paris)FAN1
WikiGenes22909
SOURCE (Princeton)FAN1
Genetics Home Reference (NIH)FAN1
Genomic and cartography
GoldenPath hg38 (UCSC)FAN1  -     chr15:30903873-30911788 +  15q13.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)FAN1  -     15q13.3   [Description]    (hg19-Feb_2009)
EnsemblFAN1 - 15q13.3 [CytoView hg19]  FAN1 - 15q13.3 [CytoView hg38]
Mapping of homologs : NCBIFAN1 [Mapview hg19]  FAN1 [Mapview hg38]
OMIM613534   614817   
Gene and transcription
Genbank (Entrez)AB023235 AK026787 AK290987 BC044890 BC047882
RefSeq transcript (Entrez)NM_001146094 NM_001146095 NM_001146096 NM_014967
RefSeq genomic (Entrez)NC_000015 NC_018926 NG_032946 NT_187660 NW_011332701
Consensus coding sequences : CCDS (NCBI)FAN1
Cluster EST : UnigeneHs.734213 [ NCBI ]
CGAP (NCI)Hs.734213
Alternative Splicing GalleryENSG00000198690
Gene ExpressionFAN1 [ NCBI-GEO ]   FAN1 [ EBI - ARRAY_EXPRESS ]   FAN1 [ SEEK ]   FAN1 [ MEM ]
Gene Expression Viewer (FireBrowse)FAN1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)22909
GTEX Portal (Tissue expression)FAN1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y2M0   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y2M0  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y2M0
Splice isoforms : SwissVarQ9Y2M0
PhosPhoSitePlusQ9Y2M0
Domains : Interpro (EBI)Fan1-like    VRR_NUC    Znf_Rad18_put   
Domain families : Pfam (Sanger)VRR_NUC (PF08774)   
Domain families : Pfam (NCBI)pfam08774   
Domain families : Smart (EMBL)VRR_NUC (SM00990)  ZnF_Rad18 (SM00734)  
Conserved Domain (NCBI)FAN1
DMDM Disease mutations22909
Blocks (Seattle)FAN1
PDB (SRS)4REA    4REB    4REC    4RI8    4RI9    4RIA    4RIB    4RIC    4RID    4RY3   
PDB (PDBSum)4REA    4REB    4REC    4RI8    4RI9    4RIA    4RIB    4RIC    4RID    4RY3   
PDB (IMB)4REA    4REB    4REC    4RI8    4RI9    4RIA    4RIB    4RIC    4RID    4RY3   
PDB (RSDB)4REA    4REB    4REC    4RI8    4RI9    4RIA    4RIB    4RIC    4RID    4RY3   
Structural Biology KnowledgeBase4REA    4REB    4REC    4RI8    4RI9    4RIA    4RIB    4RIC    4RID    4RY3   
SCOP (Structural Classification of Proteins)4REA    4REB    4REC    4RI8    4RI9    4RIA    4RIB    4RIC    4RID    4RY3   
CATH (Classification of proteins structures)4REA    4REB    4REC    4RI8    4RI9    4RIA    4RIB    4RIC    4RID    4RY3   
SuperfamilyQ9Y2M0
Human Protein AtlasENSG00000198690
Peptide AtlasQ9Y2M0
HPRD17205
IPIIPI00007317   IPI00793895   
Protein Interaction databases
DIP (DOE-UCLA)Q9Y2M0
IntAct (EBI)Q9Y2M0
FunCoupENSG00000198690
BioGRIDFAN1
STRING (EMBL)FAN1
ZODIACFAN1
Ontologies - Pathways
QuickGOQ9Y2M0
Ontology : AmiGOmagnesium ion binding  double-strand break repair via homologous recombination  phosphodiesterase I activity  protein binding  nucleus  nucleoplasm  nucleoplasm  cytosol  DNA repair  nucleotide-excision repair  5'-3' exonuclease activity  5'-flap endonuclease activity  nucleotide-excision repair, DNA incision  nucleotide-excision repair, DNA incision  interstrand cross-link repair  interstrand cross-link repair  ubiquitin binding  intercellular bridge  flap-structured DNA binding  
Ontology : EGO-EBImagnesium ion binding  double-strand break repair via homologous recombination  phosphodiesterase I activity  protein binding  nucleus  nucleoplasm  nucleoplasm  cytosol  DNA repair  nucleotide-excision repair  5'-3' exonuclease activity  5'-flap endonuclease activity  nucleotide-excision repair, DNA incision  nucleotide-excision repair, DNA incision  interstrand cross-link repair  interstrand cross-link repair  ubiquitin binding  intercellular bridge  flap-structured DNA binding  
Pathways : KEGGFanconi anemia pathway   
NDEx NetworkFAN1
Atlas of Cancer Signalling NetworkFAN1
Wikipedia pathwaysFAN1
Orthology - Evolution
OrthoDB22909
GeneTree (enSembl)ENSG00000198690
Phylogenetic Trees/Animal Genes : TreeFamFAN1
HOVERGENQ9Y2M0
HOGENOMQ9Y2M0
Homologs : HomoloGeneFAN1
Homology/Alignments : Family Browser (UCSC)FAN1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerFAN1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)FAN1
dbVarFAN1
ClinVarFAN1
1000_GenomesFAN1 
Exome Variant ServerFAN1
ExAC (Exome Aggregation Consortium)FAN1 (select the gene name)
Genetic variants : HAPMAP22909
Genomic Variants (DGV)FAN1 [DGVbeta]
DECIPHERFAN1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisFAN1 
Mutations
ICGC Data PortalFAN1 
TCGA Data PortalFAN1 
Broad Tumor PortalFAN1
OASIS PortalFAN1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICFAN1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDFAN1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch FAN1
DgiDB (Drug Gene Interaction Database)FAN1
DoCM (Curated mutations)FAN1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)FAN1 (select a term)
intoGenFAN1
Cancer3DFAN1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM613534    614817   
Orphanet3245    22865   
MedgenFAN1
Genetic Testing Registry FAN1
NextProtQ9Y2M0 [Medical]
TSGene22909
GENETestsFAN1
Target ValidationFAN1
Huge Navigator FAN1 [HugePedia]
snp3D : Map Gene to Disease22909
BioCentury BCIQFAN1
ClinGenFAN1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD22909
Chemical/Pharm GKB GenePA165478601
Clinical trialFAN1
Miscellaneous
canSAR (ICR)FAN1 (select the gene name)
Probes
Litterature
PubMed27 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineFAN1
EVEXFAN1
GoPubMedFAN1
iHOPFAN1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 12:33:25 CEST 2017

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