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FAR1 (fatty acyl-CoA reductase 1)

Identity

Alias_namesMLSTD2
male sterility domain containing 2
Alias_symbol (synonym)FLJ22728
SDR10E1
Other aliasPFCRD
HGNC (Hugo) FAR1
LocusID (NCBI) 84188
Atlas_Id 63294
Location 11p15.3  [Link to chromosome band 11p15]
Location_base_pair Starts at 13668659 and ends at 13732346 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
A2M (12p13.31) / FAR1 (11p15.2)AZGP1 (7q22.1) / FAR1 (11p15.2)CTNNB1 (3p22.1) / FAR1 (11p15.2)
CTSB (8p23.1) / FAR1 (11p15.2)ELOVL5 (6p12.1) / FAR1 (11p15.2)FAR1 (11p15.2) / AP000769.1 ()
FAR1 (11p15.2) / FAR1 (11p15.2)FLYWCH1 (16p13.3) / FAR1 (11p15.2)FSCN1 (7p22.1) / FAR1 (11p15.2)
GRN (17q21.31) / FAR1 (11p15.2)GSN (9q33.2) / FAR1 (11p15.2)MPO (17q22) / FAR1 (11p15.2)
PAEP (9q34.3) / FAR1 (11p15.2)PDGFRB (5q32) / FAR1 (11p15.2)PHKB (16q12.1) / FAR1 (11p15.2)
UGGT1 (2q14.3) / FAR1 (11p15.2)GRN FAR1FLYWCH1 FAR1
UGGT1 FAR1PDGFRB FAR1CTSB FAR1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)FAR1   26222
Cards
Entrez_Gene (NCBI)FAR1  84188  fatty acyl-CoA reductase 1
AliasesMLSTD2; PFCRD; SDR10E1
GeneCards (Weizmann)FAR1
Ensembl hg19 (Hinxton)ENSG00000197601 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000197601 [Gene_View]  chr11:13668659-13732346 [Contig_View]  FAR1 [Vega]
ICGC DataPortalENSG00000197601
TCGA cBioPortalFAR1
AceView (NCBI)FAR1
Genatlas (Paris)FAR1
WikiGenes84188
SOURCE (Princeton)FAR1
Genetics Home Reference (NIH)FAR1
Genomic and cartography
GoldenPath hg38 (UCSC)FAR1  -     chr11:13668659-13732346 +  11p15.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)FAR1  -     11p15.3   [Description]    (hg19-Feb_2009)
EnsemblFAR1 - 11p15.3 [CytoView hg19]  FAR1 - 11p15.3 [CytoView hg38]
Mapping of homologs : NCBIFAR1 [Mapview hg19]  FAR1 [Mapview hg38]
OMIM616107   616154   
Gene and transcription
Genbank (Entrez)AF086349 AK024967 AK026381 AK090880 AK315527
RefSeq transcript (Entrez)NM_032228
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)FAR1
Cluster EST : UnigeneHs.501991 [ NCBI ]
CGAP (NCI)Hs.501991
Alternative Splicing GalleryENSG00000197601
Gene ExpressionFAR1 [ NCBI-GEO ]   FAR1 [ EBI - ARRAY_EXPRESS ]   FAR1 [ SEEK ]   FAR1 [ MEM ]
Gene Expression Viewer (FireBrowse)FAR1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)84188
GTEX Portal (Tissue expression)FAR1
Human Protein AtlasENSG00000197601-FAR1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8WVX9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8WVX9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8WVX9
Splice isoforms : SwissVarQ8WVX9
Catalytic activity : Enzyme1.2.1.n2 [ Enzyme-Expasy ]   1.2.1.n21.2.1.n2 [ IntEnz-EBI ]   1.2.1.n2 [ BRENDA ]   1.2.1.n2 [ KEGG ]   
PhosPhoSitePlusQ8WVX9
Domains : Interpro (EBI)FAR    FAR_C    Male_sterile_NAD-bd    NAD(P)-bd_dom   
Domain families : Pfam (Sanger)NAD_binding_4 (PF07993)    Sterile (PF03015)   
Domain families : Pfam (NCBI)pfam07993    pfam03015   
Conserved Domain (NCBI)FAR1
DMDM Disease mutations84188
Blocks (Seattle)FAR1
SuperfamilyQ8WVX9
Human Protein Atlas [tissue]ENSG00000197601-FAR1 [tissue]
Peptide AtlasQ8WVX9
HPRD14724
IPIIPI00478838   IPI00975671   IPI00976270   
Protein Interaction databases
DIP (DOE-UCLA)Q8WVX9
IntAct (EBI)Q8WVX9
FunCoupENSG00000197601
BioGRIDFAR1
STRING (EMBL)FAR1
ZODIACFAR1
Ontologies - Pathways
QuickGOQ8WVX9
Ontology : AmiGOperoxisome  peroxisomal membrane  peroxisomal matrix  ether lipid biosynthetic process  wax biosynthetic process  integral component of membrane  oxidoreductase activity  long-chain fatty-acyl-CoA metabolic process  glycerophospholipid biosynthetic process  long-chain-fatty-acyl-CoA reductase activity  oxidation-reduction process  fatty-acyl-CoA reductase (alcohol-forming) activity  
Ontology : EGO-EBIperoxisome  peroxisomal membrane  peroxisomal matrix  ether lipid biosynthetic process  wax biosynthetic process  integral component of membrane  oxidoreductase activity  long-chain fatty-acyl-CoA metabolic process  glycerophospholipid biosynthetic process  long-chain-fatty-acyl-CoA reductase activity  oxidation-reduction process  fatty-acyl-CoA reductase (alcohol-forming) activity  
Pathways : KEGGPeroxisome   
NDEx NetworkFAR1
Atlas of Cancer Signalling NetworkFAR1
Wikipedia pathwaysFAR1
Orthology - Evolution
OrthoDB84188
GeneTree (enSembl)ENSG00000197601
Phylogenetic Trees/Animal Genes : TreeFamFAR1
HOVERGENQ8WVX9
HOGENOMQ8WVX9
Homologs : HomoloGeneFAR1
Homology/Alignments : Family Browser (UCSC)FAR1
Gene fusions - Rearrangements
Fusion: TCGAGRN FAR1
Fusion: TCGAFLYWCH1 FAR1
Fusion: TCGAUGGT1 FAR1
Fusion: TCGAPDGFRB FAR1
Fusion: TCGACTSB FAR1
Fusion: Tumor Portal FAR1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerFAR1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)FAR1
dbVarFAR1
ClinVarFAR1
1000_GenomesFAR1 
Exome Variant ServerFAR1
ExAC (Exome Aggregation Consortium)ENSG00000197601
GNOMAD BrowserENSG00000197601
Genetic variants : HAPMAP84188
Genomic Variants (DGV)FAR1 [DGVbeta]
DECIPHERFAR1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisFAR1 
Mutations
ICGC Data PortalFAR1 
TCGA Data PortalFAR1 
Broad Tumor PortalFAR1
OASIS PortalFAR1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICFAR1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDFAR1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch FAR1
DgiDB (Drug Gene Interaction Database)FAR1
DoCM (Curated mutations)FAR1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)FAR1 (select a term)
intoGenFAR1
Cancer3DFAR1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM616107    616154   
Orphanet23367   
MedgenFAR1
Genetic Testing Registry FAR1
NextProtQ8WVX9 [Medical]
TSGene84188
GENETestsFAR1
Target ValidationFAR1
Huge Navigator FAR1 [HugePedia]
snp3D : Map Gene to Disease84188
BioCentury BCIQFAR1
ClinGenFAR1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD84188
Chemical/Pharm GKB GenePA162388007
Clinical trialFAR1
Miscellaneous
canSAR (ICR)FAR1 (select the gene name)
Probes
Litterature
PubMed22 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineFAR1
EVEXFAR1
GoPubMedFAR1
iHOPFAR1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Nov 9 11:47:30 CET 2017

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