Atlas of Genetics and Cytogenetics in Oncology and Haematology

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FAR2 (fatty acyl-CoA reductase 2)

Identity

Alias (NCBI)HEL-S-81
MLSTD1
SDR10E2
HGNC (Hugo) FAR2
HGNC Alias symbFLJ10462
SDR10E2
HGNC Alias nameshort chain dehydrogenase/reductase family 10E, member 2
HGNC Previous nameMLSTD1
HGNC Previous namemale sterility domain containing 1
LocusID (NCBI) 55711
Atlas_Id 63295
Location 12p11.22  [Link to chromosome band 12p11]
Location_base_pair Starts at 29223623 and ends at 29335616 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
AMN1 (12p11.21) / FAR2 (12p11.22)CCDC91 (12p11.22) / FAR2 (12p11.22)FAR2 (12p11.22) / MKX (10p12.1)
SMAP1 (6q13) / FAR2 (12p11.22)CCDC91 FAR2AMN1 FAR2
SMAP1 FAR2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 3 ]
  t(6;12)(q13;p11) SMAP1/FAR2
AMN1/FAR2 (12p11)
CCDC91/FAR2 (12p11)

External links

Nomenclature
HGNC (Hugo)FAR2   25531
Cards
Entrez_Gene (NCBI)FAR2    fatty acyl-CoA reductase 2
AliasesHEL-S-81; MLSTD1; SDR10E2
GeneCards (Weizmann)FAR2
Ensembl hg19 (Hinxton)ENSG00000064763 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000064763 [Gene_View]  ENSG00000064763 [Sequence]  chr12:29223623-29335616 [Contig_View]  FAR2 [Vega]
ICGC DataPortalENSG00000064763
TCGA cBioPortalFAR2
AceView (NCBI)FAR2
Genatlas (Paris)FAR2
SOURCE (Princeton)FAR2
Genetics Home Reference (NIH)FAR2
Genomic and cartography
GoldenPath hg38 (UCSC)FAR2  -     chr12:29223623-29335616 +  12p11.22   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)FAR2  -     12p11.22   [Description]    (hg19-Feb_2009)
GoldenPathFAR2 - 12p11.22 [CytoView hg19]  FAR2 - 12p11.22 [CytoView hg38]
ImmunoBaseENSG00000064763
genome Data Viewer NCBIFAR2 [Mapview hg19]  
OMIM616156   
Gene and transcription
Genbank (Entrez)AK001324 AK001927 AK027756 AK129857 AK314670
RefSeq transcript (Entrez)NM_001271783 NM_001271784 NM_018099
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)FAR2
Alternative Splicing GalleryENSG00000064763
Gene ExpressionFAR2 [ NCBI-GEO ]   FAR2 [ EBI - ARRAY_EXPRESS ]   FAR2 [ SEEK ]   FAR2 [ MEM ]
Gene Expression Viewer (FireBrowse)FAR2 [ Firebrowse - Broad ]
GenevisibleExpression of FAR2 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)55711
GTEX Portal (Tissue expression)FAR2
Human Protein AtlasENSG00000064763-FAR2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96K12   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96K12  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96K12
Splice isoforms : SwissVarQ96K12
PhosPhoSitePlusQ96K12
Domains : Interpro (EBI)FAR    FAR_C    Male_sterile_NAD-bd    NAD(P)-bd_dom_sf   
Domain families : Pfam (Sanger)NAD_binding_4 (PF07993)    Sterile (PF03015)   
Domain families : Pfam (NCBI)pfam07993    pfam03015   
Conserved Domain (NCBI)FAR2
Blocks (Seattle)FAR2
SuperfamilyQ96K12
Human Protein Atlas [tissue]ENSG00000064763-FAR2 [tissue]
Peptide AtlasQ96K12
HPRD14723
IPIIPI00789529   IPI01021605   IPI01021738   IPI01023063   IPI01020823   IPI01020957   
Protein Interaction databases
DIP (DOE-UCLA)Q96K12
IntAct (EBI)Q96K12
BioGRIDFAR2
STRING (EMBL)FAR2
ZODIACFAR2
Ontologies - Pathways
QuickGOQ96K12
Ontology : AmiGOperoxisome  peroxisome  integral component of peroxisomal membrane  peroxisomal matrix  lipid metabolic process  wax biosynthetic process  oxidoreductase activity  long-chain fatty-acyl-CoA metabolic process  long-chain fatty-acyl-CoA metabolic process  oxidation-reduction process  fatty-acyl-CoA reductase (alcohol-forming) activity  fatty-acyl-CoA reductase (alcohol-forming) activity  alcohol-forming fatty acyl-CoA reductase activity  
Ontology : EGO-EBIperoxisome  peroxisome  integral component of peroxisomal membrane  peroxisomal matrix  lipid metabolic process  wax biosynthetic process  oxidoreductase activity  long-chain fatty-acyl-CoA metabolic process  long-chain fatty-acyl-CoA metabolic process  oxidation-reduction process  fatty-acyl-CoA reductase (alcohol-forming) activity  fatty-acyl-CoA reductase (alcohol-forming) activity  alcohol-forming fatty acyl-CoA reductase activity  
NDEx NetworkFAR2
Atlas of Cancer Signalling NetworkFAR2
Wikipedia pathwaysFAR2
Orthology - Evolution
OrthoDB55711
GeneTree (enSembl)ENSG00000064763
Phylogenetic Trees/Animal Genes : TreeFamFAR2
HOGENOMQ96K12
Homologs : HomoloGeneFAR2
Homology/Alignments : Family Browser (UCSC)FAR2
Gene fusions - Rearrangements
Fusion PortalCCDC91 FAR2
Fusion PortalAMN1 FAR2
Fusion PortalSMAP1 FAR2
Fusion : QuiverFAR2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerFAR2 [hg38]
dbVarFAR2
ClinVarFAR2
MonarchFAR2
1000_GenomesFAR2 
Exome Variant ServerFAR2
GNOMAD BrowserENSG00000064763
Varsome BrowserFAR2
Genomic Variants (DGV)FAR2 [DGVbeta]
DECIPHERFAR2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisFAR2 
Mutations
ICGC Data PortalFAR2 
TCGA Data PortalFAR2 
Broad Tumor PortalFAR2
OASIS PortalFAR2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICFAR2  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DFAR2
Mutations and Diseases : HGMDFAR2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch FAR2
DgiDB (Drug Gene Interaction Database)FAR2
DoCM (Curated mutations)FAR2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)FAR2 (select a term)
intoGenFAR2
Cancer3DFAR2(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM616156   
Orphanet
DisGeNETFAR2
MedgenFAR2
Genetic Testing Registry FAR2
NextProtQ96K12 [Medical]
GENETestsFAR2
Target ValidationFAR2
Huge Navigator FAR2 [HugePedia]
ClinGenFAR2
Clinical trials, drugs, therapy
MyCancerGenomeFAR2
Protein Interactions : CTD
Pharm GKB GenePA162388036
Clinical trialFAR2
Miscellaneous
canSAR (ICR)FAR2 (select the gene name)
HarmonizomeFAR2
DataMed IndexFAR2
Probes
Litterature
PubMed16 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineFAR2
EVEXFAR2
GoPubMedFAR2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Sat Dec 5 16:54:23 CET 2020
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