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FARP1 (FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived))

Identity

Other namesCDEP
PLEKHC2
PPP1R75
HGNC (Hugo) FARP1
LocusID (NCBI) 10160
Location 13q32.2
Location_base_pair Starts at 98795434 and ends at 98897558 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)FARP1   3591
Entrez_Gene (NCBI)FARP1  10160  FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
Cards
GeneCards (Weizmann)FARP1
Ensembl (Hinxton)ENSG00000152767 [Gene_View]  chr13:98795434-98897558 [Contig_View]  FARP1 [Vega]
AceView (NCBI)FARP1
Genatlas (Paris)FARP1
SOURCE (Stanford)NM_001001715 NM_005766
Genomic and cartography
GoldenPath (UCSC)FARP1  -  13q32.2   chr13:98795434-98897558 +  13q32.2   [Description]    (hg19-Feb_2009)
EnsemblFARP1 - 13q32.2 [CytoView]
Mapping of homologs : NCBIFARP1 [Mapview]
OMIM602654   
Gene and transcription
Genbank (Entrez)AB008430 AI273567 AI274149 AK095747 AK123565
RefSeq transcript (SRS)NM_001001715 NM_005766
RefSeq transcript (Entrez)NM_001001715 NM_005766
RefSeq genomic (SRS)AC_000145 NC_000013 NC_018924 NT_009952 NW_001838084 NW_004078077
RefSeq genomic (Entrez)AC_000145 NC_000013 NC_018924 NT_009952 NW_001838084 NW_004078077
Consensus coding sequences : CCDS (NCBI)FARP1
Cluster EST : UnigeneHs.403917 [ SRS ] Hs.403917 [ NCBI ]
CGAP (NCI)Hs.403917
Alternative Splicing : Fast-db (Paris)GSHG0008239
Alternative Splicing GalleryENSG00000152767
Gene ExpressionFARP1 [ NCBI-GEO ]   FARP1 [ EBI - ARRAY_EXPRESS ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y4F1 (SRS) Q9Y4F1 (Uniprot)
NextProtQ9Y4F1
With graphics : InterProQ9Y4F1
Splice isoforms : SwissVarQ9Y4F1(Swissvar)
Domaine pattern : Prosite (SRS)DH_1 (PS00741)    DH_2 (PS50010)    FERM_1 (PS00660)    FERM_2 (PS00661)    FERM_3 (PS50057)    PH_DOMAIN (PS50003)   
Domaine pattern : Prosite (Expaxy)DH_1 (PS00741)    DH_2 (PS50010)    FERM_1 (PS00660)    FERM_2 (PS00661)    FERM_3 (PS50057)    PH_DOMAIN (PS50003)   
Domains : Interpro (SRS)Band_41_domain    Band_41_fam    DH-domain    Ez/rad/moesin    FERM-adjacent    FERM/acyl-CoA-bd_prot_3-hlx    FERM_central    FERM_CS    FERM_domain    FERM_N    FERM_PH-like_C    PH_like_dom    Pleckstrin_homology   
Domains : Interpro (EBI)Band_41_domain    Band_41_fam    DH-domain    Ez/rad/moesin    FERM-adjacent    FERM/acyl-CoA-bd_prot_3-hlx    FERM_central    FERM_CS    FERM_domain    FERM_N    FERM_PH-like_C    PH_like_dom    Pleckstrin_homology   
Related proteins : CluSTrQ9Y4F1
Domain families : Pfam (SRS)FA (PF08736)    FERM_C (PF09380)    FERM_M (PF00373)    FERM_N (PF09379)    PH (PF00169)    RhoGEF (PF00621)   
Domain families : Pfam (Sanger)FA (PF08736)    FERM_C (PF09380)    FERM_M (PF00373)    FERM_N (PF09379)    PH (PF00169)    RhoGEF (PF00621)   
Domain families : Pfam (NCBI)pfam08736    pfam09380    pfam00373    pfam09379    pfam00169    pfam00621   
Domain families : Smart (EMBL)B41 (SM00295)  PH (SM00233)  RhoGEF (SM00325)  
DMDM10160
Blocks (Seattle)Q9Y4F1
Human Protein AtlasENSG00000152767
IPIIPI00024773   IPI00746455   IPI00418590   IPI01018855   IPI00553014   IPI00552839   
Protein Interaction databases
DIP (DOE-UCLA)Q9Y4F1
IntAct (EBI)Q9Y4F1
FunCoupENSG00000152767
REACTOMEFARP1
Protein Interaction Database10160
BioGRIDFARP1
InParanoidQ9Y4F1
Interologous Interaction database Q9Y4F1
IntegromeDBFARP1
Polymorphism : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)FARP1
SNP (GeneSNP Utah)FARP1
SNP : HGBaseFARP1
Genetic variants : HAPMAPFARP1
Somatic Mutations in Cancer : COSMICFARP1 
CONAN: Copy Number AnalysisFARP1 
Mutations and Diseases : HGMDFARP1
OMIM602654   
GENETests602654   
Disease Genetic AssociationFARP1
Huge Navigator FARP1 [HugePedia]  FARP1 [HugeCancerGEM]
Genomic VariantsFARP1  FARP1 [DGVbeta]
snp3D : Map Gene to Disease10160
General knowledge
Homologs : HomoloGeneFARP1
Homology/Alignments : Family Browser (UCSC)FARP1
Phylogenetic Trees/Animal Genes : TreeFamFARP1
Chemical/Protein Interactions : CTD10160
Chemical/Pharm GKB GenePA28004
Clinical trialFARP1
Cancer Resource (Charite)ENSG00000152767
Ontology : AmiGORho guanyl-nucleotide exchange factor activity  phospholipid binding  cytoplasm  cytoskeleton  cytoskeletal protein binding  negative regulation of phosphatase activity  extrinsic to membrane  regulation of Rho protein signal transduction  
Ontology : EGO-EBIRho guanyl-nucleotide exchange factor activity  phospholipid binding  cytoplasm  cytoskeleton  cytoskeletal protein binding  negative regulation of phosphatase activity  extrinsic to membrane  regulation of Rho protein signal transduction  
Other databases
Probes
Litterature
PubMed17 Pubmed reference(s) in Entrez
PubGeneFARP1
iHOPFARP1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated01-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed May 1 12:24:17 CEST 2013
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