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FARSB (phenylalanyl-tRNA synthetase subunit beta)

Identity

Alias_namesFARSLB
phenylalanyl-tRNA synthetase-like, beta subunit
phenylalanyl-tRNA synthetase, beta subunit
Alias_symbol (synonym)PheHB
FRSB
Other aliasHSPC173
NEDBLLA
PheRS
RILDBC
HGNC (Hugo) FARSB
LocusID (NCBI) 10056
Atlas_Id 63300
Location 2q36.1  [Link to chromosome band 2q36]
Location_base_pair Starts at 222571443 and ends at 222656355 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
AQR (15q14) / FARSB (2q36.1)BTBD7 (14q32.12) / FARSB (2q36.1)FARSB (2q36.1) / BTBD7 (14q32.12)
FARSB (2q36.1) / TRIM61 (4q32.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)FARSB   17800
Cards
Entrez_Gene (NCBI)FARSB  10056  phenylalanyl-tRNA synthetase subunit beta
AliasesFARSLB; FRSB; HSPC173; NEDBLLA; 
PheHB; PheRS; RILDBC
GeneCards (Weizmann)FARSB
Ensembl hg19 (Hinxton)ENSG00000116120 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000116120 [Gene_View]  ENSG00000116120 [Sequence]  chr2:222571443-222656355 [Contig_View]  FARSB [Vega]
ICGC DataPortalENSG00000116120
TCGA cBioPortalFARSB
AceView (NCBI)FARSB
Genatlas (Paris)FARSB
WikiGenes10056
SOURCE (Princeton)FARSB
Genetics Home Reference (NIH)FARSB
Genomic and cartography
GoldenPath hg38 (UCSC)FARSB  -     chr2:222571443-222656355 -  2q36.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)FARSB  -     2q36.1   [Description]    (hg19-Feb_2009)
GoldenPathFARSB - 2q36.1 [CytoView hg19]  FARSB - 2q36.1 [CytoView hg38]
ImmunoBaseENSG00000116120
Mapping of homologs : NCBIFARSB [Mapview hg19]  FARSB [Mapview hg38]
OMIM609690   613658   
Gene and transcription
Genbank (Entrez)AF042346 AF161521 AK001025 AK055289 AK291531
RefSeq transcript (Entrez)NM_005687
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)FARSB
Cluster EST : UnigeneHs.471452 [ NCBI ]
CGAP (NCI)Hs.471452
Alternative Splicing GalleryENSG00000116120
Gene ExpressionFARSB [ NCBI-GEO ]   FARSB [ EBI - ARRAY_EXPRESS ]   FARSB [ SEEK ]   FARSB [ MEM ]
Gene Expression Viewer (FireBrowse)FARSB [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10056
GTEX Portal (Tissue expression)FARSB
Human Protein AtlasENSG00000116120-FARSB [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NSD9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NSD9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NSD9
Splice isoforms : SwissVarQ9NSD9
Catalytic activity : Enzyme6.1.1.20 [ Enzyme-Expasy ]   6.1.1.206.1.1.20 [ IntEnz-EBI ]   6.1.1.20 [ BRENDA ]   6.1.1.20 [ KEGG ]   
PhosPhoSitePlusQ9NSD9
Domaine pattern : Prosite (Expaxy)B5 (PS51483)   
Domains : Interpro (EBI)B3/B4_tRNA-bd    DNA-bd_dom_put_sf    Phe-tRNA-synth_IIc_bsu_arc    Phe-tRNA_synthase_B3/B4    tRNA_synthase_B5-dom   
Domain families : Pfam (Sanger)B3_4 (PF03483)    B5 (PF03484)   
Domain families : Pfam (NCBI)pfam03483    pfam03484   
Domain families : Smart (EMBL)B3_4 (SM00873)  B5 (SM00874)  
Conserved Domain (NCBI)FARSB
DMDM Disease mutations10056
Blocks (Seattle)FARSB
PDB (RSDB)3L4G   
PDB Europe3L4G   
PDB (PDBSum)3L4G   
PDB (IMB)3L4G   
Structural Biology KnowledgeBase3L4G   
SCOP (Structural Classification of Proteins)3L4G   
CATH (Classification of proteins structures)3L4G   
SuperfamilyQ9NSD9
Human Protein Atlas [tissue]ENSG00000116120-FARSB [tissue]
Peptide AtlasQ9NSD9
HPRD09947
IPIIPI00300074   IPI01009249   
Protein Interaction databases
DIP (DOE-UCLA)Q9NSD9
IntAct (EBI)Q9NSD9
FunCoupENSG00000116120
BioGRIDFARSB
STRING (EMBL)FARSB
ZODIACFARSB
Ontologies - Pathways
QuickGOQ9NSD9
Ontology : AmiGOmagnesium ion binding  RNA binding  phenylalanine-tRNA ligase activity  phenylalanine-tRNA ligase activity  protein binding  ATP binding  cytoplasm  cytosol  translation  tRNA aminoacylation for protein translation  phenylalanyl-tRNA aminoacylation  phenylalanyl-tRNA aminoacylation  phenylalanine-tRNA ligase complex  phenylalanine-tRNA ligase complex  membrane  protein heterotetramerization  
Ontology : EGO-EBImagnesium ion binding  RNA binding  phenylalanine-tRNA ligase activity  phenylalanine-tRNA ligase activity  protein binding  ATP binding  cytoplasm  cytosol  translation  tRNA aminoacylation for protein translation  phenylalanyl-tRNA aminoacylation  phenylalanyl-tRNA aminoacylation  phenylalanine-tRNA ligase complex  phenylalanine-tRNA ligase complex  membrane  protein heterotetramerization  
Pathways : KEGGAminoacyl-tRNA biosynthesis    Phenylalanine, tyrosine and tryptophan biosynthesis   
NDEx NetworkFARSB
Atlas of Cancer Signalling NetworkFARSB
Wikipedia pathwaysFARSB
Orthology - Evolution
OrthoDB10056
GeneTree (enSembl)ENSG00000116120
Phylogenetic Trees/Animal Genes : TreeFamFARSB
HOGENOMQ9NSD9
Homologs : HomoloGeneFARSB
Homology/Alignments : Family Browser (UCSC)FARSB
Gene fusions - Rearrangements
Fusion : QuiverFARSB
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerFARSB [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)FARSB
dbVarFARSB
ClinVarFARSB
1000_GenomesFARSB 
Exome Variant ServerFARSB
ExAC (Exome Aggregation Consortium)ENSG00000116120
GNOMAD BrowserENSG00000116120
Varsome BrowserFARSB
Genetic variants : HAPMAP10056
Genomic Variants (DGV)FARSB [DGVbeta]
DECIPHERFARSB [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisFARSB 
Mutations
ICGC Data PortalFARSB 
TCGA Data PortalFARSB 
Broad Tumor PortalFARSB
OASIS PortalFARSB [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICFARSB  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DFARSB
Mutations and Diseases : HGMDFARSB
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch FARSB
DgiDB (Drug Gene Interaction Database)FARSB
DoCM (Curated mutations)FARSB (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)FARSB (select a term)
intoGenFARSB
Cancer3DFARSB(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609690    613658   
Orphanet
DisGeNETFARSB
MedgenFARSB
Genetic Testing Registry FARSB
NextProtQ9NSD9 [Medical]
TSGene10056
GENETestsFARSB
Target ValidationFARSB
Huge Navigator FARSB [HugePedia]
snp3D : Map Gene to Disease10056
BioCentury BCIQFARSB
ClinGenFARSB
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD10056
Chemical/Pharm GKB GenePA162388068
Clinical trialFARSB
Miscellaneous
canSAR (ICR)FARSB (select the gene name)
DataMed IndexFARSB
Probes
Litterature
PubMed51 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineFARSB
EVEXFARSB
GoPubMedFARSB
iHOPFARSB
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Sep 3 15:28:21 CEST 2019
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