Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

FAT2 (FAT atypical cadherin 2)

Identity

Alias_namesFAT tumor suppressor (Drosophila) homolog 2
FAT tumor suppressor homolog 2 (Drosophila)
Alias_symbol (synonym)MEGF1
CDHF8
HFAT2
CDHR9
Other alias
HGNC (Hugo) FAT2
LocusID (NCBI) 2196
Atlas_Id 40535
Location 5q33.1  [Link to chromosome band 5q33]
Location_base_pair Starts at 151504092 and ends at 151568944 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
NSD1 (5q35.2) / FAT2 (5q33.1)NSD1 5q35.2 / FAT2 5q33.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)FAT2   3596
Cards
Entrez_Gene (NCBI)FAT2  2196  FAT atypical cadherin 2
AliasesCDHF8; CDHR9; HFAT2; MEGF1
GeneCards (Weizmann)FAT2
Ensembl hg19 (Hinxton)ENSG00000086570 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000086570 [Gene_View]  chr5:151504092-151568944 [Contig_View]  FAT2 [Vega]
ICGC DataPortalENSG00000086570
TCGA cBioPortalFAT2
AceView (NCBI)FAT2
Genatlas (Paris)FAT2
WikiGenes2196
SOURCE (Princeton)FAT2
Genetics Home Reference (NIH)FAT2
Genomic and cartography
GoldenPath hg38 (UCSC)FAT2  -     chr5:151504092-151568944 -  5q33.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)FAT2  -     5q33.1   [Description]    (hg19-Feb_2009)
EnsemblFAT2 - 5q33.1 [CytoView hg19]  FAT2 - 5q33.1 [CytoView hg38]
Mapping of homologs : NCBIFAT2 [Mapview hg19]  FAT2 [Mapview hg38]
OMIM604269   
Gene and transcription
Genbank (Entrez)AB011535 AB160984 AB177851 AF231022 AK308619
RefSeq transcript (Entrez)NM_001447
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)FAT2
Cluster EST : UnigeneHs.591255 [ NCBI ]
CGAP (NCI)Hs.591255
Alternative Splicing GalleryENSG00000086570
Gene ExpressionFAT2 [ NCBI-GEO ]   FAT2 [ EBI - ARRAY_EXPRESS ]   FAT2 [ SEEK ]   FAT2 [ MEM ]
Gene Expression Viewer (FireBrowse)FAT2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2196
GTEX Portal (Tissue expression)FAT2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NYQ8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NYQ8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NYQ8
Splice isoforms : SwissVarQ9NYQ8
PhosPhoSitePlusQ9NYQ8
Domaine pattern : Prosite (Expaxy)CADHERIN_1 (PS00232)    CADHERIN_2 (PS50268)    EGF_1 (PS00022)    EGF_2 (PS01186)    EGF_3 (PS50026)    LAM_G_DOMAIN (PS50025)   
Domains : Interpro (EBI)Cadherin    Cadherin-like    Cadherin_CS    ConA-like_dom    EGF-like_Ca-bd_dom    EGF-like_CS    EGF-like_dom    Laminin_G   
Domain families : Pfam (Sanger)Cadherin (PF00028)    EGF (PF00008)    Laminin_G_2 (PF02210)   
Domain families : Pfam (NCBI)pfam00028    pfam00008    pfam02210   
Domain families : Smart (EMBL)CA (SM00112)  EGF (SM00181)  EGF_CA (SM00179)  LamG (SM00282)  
Conserved Domain (NCBI)FAT2
DMDM Disease mutations2196
Blocks (Seattle)FAT2
SuperfamilyQ9NYQ8
Human Protein AtlasENSG00000086570
Peptide AtlasQ9NYQ8
HPRD05041
IPIIPI00302641   IPI00749416   
Protein Interaction databases
DIP (DOE-UCLA)Q9NYQ8
IntAct (EBI)Q9NYQ8
FunCoupENSG00000086570
BioGRIDFAT2
STRING (EMBL)FAT2
ZODIACFAT2
Ontologies - Pathways
QuickGOQ9NYQ8
Ontology : AmiGOcalcium ion binding  nucleus  plasma membrane  cell-cell adherens junction  homophilic cell adhesion via plasma membrane adhesion molecules  epithelial cell migration  integral component of membrane  extracellular exosome  
Ontology : EGO-EBIcalcium ion binding  nucleus  plasma membrane  cell-cell adherens junction  homophilic cell adhesion via plasma membrane adhesion molecules  epithelial cell migration  integral component of membrane  extracellular exosome  
NDEx NetworkFAT2
Atlas of Cancer Signalling NetworkFAT2
Wikipedia pathwaysFAT2
Orthology - Evolution
OrthoDB2196
GeneTree (enSembl)ENSG00000086570
Phylogenetic Trees/Animal Genes : TreeFamFAT2
HOVERGENQ9NYQ8
HOGENOMQ9NYQ8
Homologs : HomoloGeneFAT2
Homology/Alignments : Family Browser (UCSC)FAT2
Gene fusions - Rearrangements
Fusion : MitelmanNSD1/FAT2 [5q35.2/5q33.1]  [t(5;5)(q33;q35)]  
Fusion: TCGANSD1 5q35.2 FAT2 5q33.1 BLCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerFAT2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)FAT2
dbVarFAT2
ClinVarFAT2
1000_GenomesFAT2 
Exome Variant ServerFAT2
ExAC (Exome Aggregation Consortium)FAT2 (select the gene name)
Genetic variants : HAPMAP2196
Genomic Variants (DGV)FAT2 [DGVbeta]
DECIPHERFAT2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisFAT2 
Mutations
ICGC Data PortalFAT2 
TCGA Data PortalFAT2 
Broad Tumor PortalFAT2
OASIS PortalFAT2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICFAT2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDFAT2
intOGen PortalFAT2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch FAT2
DgiDB (Drug Gene Interaction Database)FAT2
DoCM (Curated mutations)FAT2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)FAT2 (select a term)
intoGenFAT2
Cancer3DFAT2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604269   
Orphanet
MedgenFAT2
Genetic Testing Registry FAT2
NextProtQ9NYQ8 [Medical]
TSGene2196
GENETestsFAT2
Target ValidationFAT2
Huge Navigator FAT2 [HugePedia]
snp3D : Map Gene to Disease2196
BioCentury BCIQFAT2
ClinGenFAT2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD2196
Chemical/Pharm GKB GenePA28009
Clinical trialFAT2
Miscellaneous
canSAR (ICR)FAT2 (select the gene name)
Probes
Litterature
PubMed9 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineFAT2
EVEXFAT2
GoPubMedFAT2
iHOPFAT2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Jun 7 12:33:28 CEST 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.