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FBLIM1 (filamin binding LIM protein 1)

Identity

Alias (NCBI)CAL
FBLP-1
FBLP1
HGNC (Hugo) FBLIM1
HGNC Alias symbFBLP-1
CAL
migfilin
LocusID (NCBI) 54751
Atlas_Id 49967
Location 1p36.21  [Link to chromosome band 1p36]
Location_base_pair Starts at 15758795 and ends at 15786589 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ESPN (1p36.31) / FBLIM1 (1p36.21)FBLIM1 (1p36.21) / AKIP1 (11p15.4)SPEN (1p36.21) / FBLIM1 (1p36.21)
TIAM1 (21q22.11) / FBLIM1 (1p36.21)TRRAP (7q22.1) / FBLIM1 (1p36.21)ESPN 1p36.31 / FBLIM1 1p36.21
SPEN 1p36.21 / FBLIM1 1p36.21TIAM1 21q22.11 / FBLIM1 1p36.21

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)FBLIM1   24686
Cards
Entrez_Gene (NCBI)FBLIM1    filamin binding LIM protein 1
AliasesCAL; FBLP-1; FBLP1
GeneCards (Weizmann)FBLIM1
Ensembl hg19 (Hinxton)ENSG00000162458 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000162458 [Gene_View]  ENSG00000162458 [Sequence]  chr1:15758795-15786589 [Contig_View]  FBLIM1 [Vega]
ICGC DataPortalENSG00000162458
TCGA cBioPortalFBLIM1
AceView (NCBI)FBLIM1
Genatlas (Paris)FBLIM1
SOURCE (Princeton)FBLIM1
Genetics Home Reference (NIH)FBLIM1
Genomic and cartography
GoldenPath hg38 (UCSC)FBLIM1  -     chr1:15758795-15786589 +  1p36.21   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)FBLIM1  -     1p36.21   [Description]    (hg19-Feb_2009)
GoldenPathFBLIM1 - 1p36.21 [CytoView hg19]  FBLIM1 - 1p36.21 [CytoView hg38]
ImmunoBaseENSG00000162458
Genome Data Viewer NCBIFBLIM1 [Mapview hg19]  
OMIM607747   
Gene and transcription
Genbank (Entrez)AF459643 AK027444 AK055259 AL133035 AW069718
RefSeq transcript (Entrez)NM_001024215 NM_001024216 NM_001350151 NM_017556
Consensus coding sequences : CCDS (NCBI)FBLIM1
Gene ExpressionFBLIM1 [ NCBI-GEO ]   FBLIM1 [ EBI - ARRAY_EXPRESS ]   FBLIM1 [ SEEK ]   FBLIM1 [ MEM ]
Gene Expression Viewer (FireBrowse)FBLIM1 [ Firebrowse - Broad ]
GenevisibleExpression of FBLIM1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)54751
GTEX Portal (Tissue expression)FBLIM1
Human Protein AtlasENSG00000162458-FBLIM1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8WUP2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8WUP2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8WUP2
PhosPhoSitePlusQ8WUP2
Domaine pattern : Prosite (Expaxy)LIM_DOMAIN_1 (PS00478)    LIM_DOMAIN_2 (PS50023)   
Domains : Interpro (EBI)Znf_LIM   
Domain families : Pfam (Sanger)LIM (PF00412)   
Domain families : Pfam (NCBI)pfam00412   
Domain families : Smart (EMBL)LIM (SM00132)  
Conserved Domain (NCBI)FBLIM1
PDB (RSDB)2K9U    2W0P    4P3W   
PDB Europe2K9U    2W0P    4P3W   
PDB (PDBSum)2K9U    2W0P    4P3W   
PDB (IMB)2K9U    2W0P    4P3W   
Structural Biology KnowledgeBase2K9U    2W0P    4P3W   
SCOP (Structural Classification of Proteins)2K9U    2W0P    4P3W   
CATH (Classification of proteins structures)2K9U    2W0P    4P3W   
SuperfamilyQ8WUP2
AlphaFold pdb e-kbQ8WUP2   
Human Protein Atlas [tissue]ENSG00000162458-FBLIM1 [tissue]
HPRD09669
Protein Interaction databases
DIP (DOE-UCLA)Q8WUP2
IntAct (EBI)Q8WUP2
BioGRIDFBLIM1
STRING (EMBL)FBLIM1
ZODIACFBLIM1
Ontologies - Pathways
QuickGOQ8WUP2
Ontology : AmiGOfibrillar center  stress fiber  stress fiber  protein binding  cytoplasm  cytosol  focal adhesion  focal adhesion  focal adhesion  regulation of cell shape  cell junction  filamin binding  filamin binding  regulation of integrin activation  cell junction assembly  metal ion binding  cell periphery  cell-cell adhesion  cell-cell adhesion  
Ontology : EGO-EBIfibrillar center  stress fiber  stress fiber  protein binding  cytoplasm  cytosol  focal adhesion  focal adhesion  focal adhesion  regulation of cell shape  cell junction  filamin binding  filamin binding  regulation of integrin activation  cell junction assembly  metal ion binding  cell periphery  cell-cell adhesion  cell-cell adhesion  
NDEx NetworkFBLIM1
Atlas of Cancer Signalling NetworkFBLIM1
Wikipedia pathwaysFBLIM1
Orthology - Evolution
OrthoDB54751
GeneTree (enSembl)ENSG00000162458
Phylogenetic Trees/Animal Genes : TreeFamFBLIM1
Homologs : HomoloGeneFBLIM1
Homology/Alignments : Family Browser (UCSC)FBLIM1
Gene fusions - Rearrangements
Fusion : MitelmanESPN/FBLIM1 [1p36.31/1p36.21]  
Fusion : MitelmanSPEN/FBLIM1 [1p36.21/1p36.21]  
Fusion : MitelmanTIAM1/FBLIM1 [21q22.11/1p36.21]  
Fusion : QuiverFBLIM1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerFBLIM1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)FBLIM1
dbVarFBLIM1
ClinVarFBLIM1
MonarchFBLIM1
1000_GenomesFBLIM1 
Exome Variant ServerFBLIM1
GNOMAD BrowserENSG00000162458
Varsome BrowserFBLIM1
ACMGFBLIM1 variants
VarityQ8WUP2
Genomic Variants (DGV)FBLIM1 [DGVbeta]
DECIPHERFBLIM1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisFBLIM1 
Mutations
ICGC Data PortalFBLIM1 
TCGA Data PortalFBLIM1 
Broad Tumor PortalFBLIM1
OASIS PortalFBLIM1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICFBLIM1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DFBLIM1
Mutations and Diseases : HGMDFBLIM1
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaFBLIM1
DgiDB (Drug Gene Interaction Database)FBLIM1
DoCM (Curated mutations)FBLIM1
CIViC (Clinical Interpretations of Variants in Cancer)FBLIM1
Cancer3DFBLIM1
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607747   
Orphanet
DisGeNETFBLIM1
MedgenFBLIM1
Genetic Testing Registry FBLIM1
NextProtQ8WUP2 [Medical]
GENETestsFBLIM1
Target ValidationFBLIM1
Huge Navigator FBLIM1 [HugePedia]
ClinGenFBLIM1
Clinical trials, drugs, therapy
MyCancerGenomeFBLIM1
Protein Interactions : CTDFBLIM1
Pharm GKB GenePA142671776
PharosQ8WUP2
Clinical trialFBLIM1
Miscellaneous
canSAR (ICR)FBLIM1
HarmonizomeFBLIM1
DataMed IndexFBLIM1
Probes
Litterature
PubMed45 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXFBLIM1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:09:03 CEST 2021

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