| Nomenclature |
|---|
| HGNC (Hugo) | FBP1 3606 |
| Cards |
|---|
| Entrez_Gene (NCBI) | FBP1 fructose-bisphosphatase 1 |
| Aliases | FBP |
| GeneCards (Weizmann) | FBP1 |
| Ensembl hg19 (Hinxton) | ENSG00000165140 [Gene_View] |
| Ensembl hg38 (Hinxton) | ENSG00000165140 [Gene_View] ENSG00000165140 [Sequence] chr9:94603139-94640263 [Contig_View] FBP1 [Vega] |
| ICGC DataPortal | ENSG00000165140 |
| TCGA cBioPortal | FBP1 |
| AceView (NCBI) | FBP1 |
| Genatlas (Paris) | FBP1 |
| SOURCE (Princeton) | FBP1 |
| Genetics Home Reference (NIH) | FBP1 |
| Genomic and cartography |
|---|
| GoldenPath hg38 (UCSC) | FBP1 - chr9:94603139-94640263 - 9q22.32 [Description] (hg38-Dec_2013) |
| GoldenPath hg19 (UCSC) | FBP1 - 9q22.32 [Description] (hg19-Feb_2009) |
| GoldenPath | FBP1 - 9q22.32 [CytoView hg19] FBP1 - 9q22.32 [CytoView hg38] |
| ImmunoBase | ENSG00000165140 |
| genome Data Viewer NCBI | FBP1 [Mapview hg19] |
| OMIM | 229700 611570 |
| Gene and transcription |
|---|
| Genbank (Entrez) | AF073475 AK223395 AK292199 AK316583 AY544122 |
| RefSeq transcript (Entrez) | NM_000507 NM_001127628 |
| RefSeq genomic (Entrez) | |
| Consensus coding sequences : CCDS (NCBI) | FBP1 |
| Alternative Splicing Gallery | ENSG00000165140 |
| Gene Expression | FBP1 [ NCBI-GEO ] FBP1 [ EBI - ARRAY_EXPRESS ]
FBP1 [ SEEK ] FBP1 [ MEM ] |
| Gene Expression Viewer (FireBrowse) | FBP1 [ Firebrowse - Broad ] |
| Genevisible | Expression of FBP1 in : [tissues] [cell-lines] [cancer] [perturbations] |
| BioGPS (Tissue expression) | 2203 |
| GTEX Portal (Tissue expression) | FBP1 |
| Human Protein Atlas | ENSG00000165140-FBP1 [pathology] [cell] [tissue] |
| Protein : pattern, domain, 3D structure |
|---|
| UniProt/SwissProt | P09467 [function] [subcellular_location] [family_and_domains] [pathology_and_biotech] [ptm_processing] [expression] [interaction] |
| NextProt | P09467 [Sequence] [Exons] [Medical] [Publications] |
| With graphics : InterPro | P09467 |
| Splice isoforms : SwissVar | P09467 |
| PhosPhoSitePlus | P09467 |
| Domaine pattern : Prosite (Expaxy) | FBPASE (PS00124) |
| Domains : Interpro (EBI) | FBPase_C_dom FBPase_class-1 FBPase_N FBPtase Fructose_bisphosphatase_AS |
| Domain families : Pfam (Sanger) | FBPase (PF00316) FBPase_C (PF18913) |
| Domain families : Pfam (NCBI) | pfam00316 pfam18913 |
| Conserved Domain (NCBI) | FBP1 |
| Blocks (Seattle) | FBP1 |
| PDB (RSDB) | 1FTA 2FHY 2FIE 2FIX 2JJK 2VT5 2WBB 2WBD 2Y5K 2Y5L 3A29 3KBZ 3KC0 3KC1 4MJO 5LDZ 5PZQ 5PZR 5PZS 5PZT 5PZU 5PZV 5PZW 5PZX 5PZY 5PZZ 5Q00 5Q01 5Q02 5Q03 5Q04 5Q05 5Q06 5Q07 5Q08 5Q09 5Q0A 5Q0B 6LS5 6LW2 7CVN |
| PDB Europe | 1FTA 2FHY 2FIE 2FIX 2JJK 2VT5 2WBB 2WBD 2Y5K 2Y5L 3A29 3KBZ 3KC0 3KC1 4MJO 5LDZ 5PZQ 5PZR 5PZS 5PZT 5PZU 5PZV 5PZW 5PZX 5PZY 5PZZ 5Q00 5Q01 5Q02 5Q03 5Q04 5Q05 5Q06 5Q07 5Q08 5Q09 5Q0A 5Q0B 6LS5 6LW2 7CVN |
| PDB (PDBSum) | 1FTA 2FHY 2FIE 2FIX 2JJK 2VT5 2WBB 2WBD 2Y5K 2Y5L 3A29 3KBZ 3KC0 3KC1 4MJO 5LDZ 5PZQ 5PZR 5PZS 5PZT 5PZU 5PZV 5PZW 5PZX 5PZY 5PZZ 5Q00 5Q01 5Q02 5Q03 5Q04 5Q05 5Q06 5Q07 5Q08 5Q09 5Q0A 5Q0B 6LS5 6LW2 7CVN |
| PDB (IMB) | 1FTA 2FHY 2FIE 2FIX 2JJK 2VT5 2WBB 2WBD 2Y5K 2Y5L 3A29 3KBZ 3KC0 3KC1 4MJO 5LDZ 5PZQ 5PZR 5PZS 5PZT 5PZU 5PZV 5PZW 5PZX 5PZY 5PZZ 5Q00 5Q01 5Q02 5Q03 5Q04 5Q05 5Q06 5Q07 5Q08 5Q09 5Q0A 5Q0B 6LS5 6LW2 7CVN |
| Structural Biology KnowledgeBase | 1FTA 2FHY 2FIE 2FIX 2JJK 2VT5 2WBB 2WBD 2Y5K 2Y5L 3A29 3KBZ 3KC0 3KC1 4MJO 5LDZ 5PZQ 5PZR 5PZS 5PZT 5PZU 5PZV 5PZW 5PZX 5PZY 5PZZ 5Q00 5Q01 5Q02 5Q03 5Q04 5Q05 5Q06 5Q07 5Q08 5Q09 5Q0A 5Q0B 6LS5 6LW2 7CVN |
| SCOP (Structural Classification of Proteins) | 1FTA 2FHY 2FIE 2FIX 2JJK 2VT5 2WBB 2WBD 2Y5K 2Y5L 3A29 3KBZ 3KC0 3KC1 4MJO 5LDZ 5PZQ 5PZR 5PZS 5PZT 5PZU 5PZV 5PZW 5PZX 5PZY 5PZZ 5Q00 5Q01 5Q02 5Q03 5Q04 5Q05 5Q06 5Q07 5Q08 5Q09 5Q0A 5Q0B 6LS5 6LW2 7CVN |
| CATH (Classification of proteins structures) | 1FTA 2FHY 2FIE 2FIX 2JJK 2VT5 2WBB 2WBD 2Y5K 2Y5L 3A29 3KBZ 3KC0 3KC1 4MJO 5LDZ 5PZQ 5PZR 5PZS 5PZT 5PZU 5PZV 5PZW 5PZX 5PZY 5PZZ 5Q00 5Q01 5Q02 5Q03 5Q04 5Q05 5Q06 5Q07 5Q08 5Q09 5Q0A 5Q0B 6LS5 6LW2 7CVN |
| Superfamily | P09467 |
| Human Protein Atlas [tissue] | ENSG00000165140-FBP1 [tissue] |
| Peptide Atlas | P09467 |
| HPRD | 01973 |
| IPI | IPI00073772 IPI00644994 |
| Protein Interaction databases |
|---|
| DIP (DOE-UCLA) | P09467 |
| IntAct (EBI) | P09467 |
| BioGRID | FBP1 |
| STRING (EMBL) | FBP1 |
| ZODIAC | FBP1 |
| Ontologies - Pathways |
|---|
| QuickGO | P09467 |
| Ontology : AmiGO | negative regulation of transcription by RNA polymerase II RNA polymerase II transcription factor binding protein binding nucleus cytoplasm cytoplasm cytosol cytosol cytosol sucrose biosynthetic process fructose metabolic process fructose 6-phosphate metabolic process fructose 6-phosphate metabolic process gluconeogenesis gluconeogenesis gluconeogenesis gluconeogenesis gluconeogenesis regulation of gluconeogenesis AMP binding dephosphorylation dephosphorylation negative regulation of cell growth fructose 1,6-bisphosphate metabolic process cellular response to drug fructose 1,6-bisphosphate 1-phosphatase activity fructose 1,6-bisphosphate 1-phosphatase activity fructose 1,6-bisphosphate 1-phosphatase activity identical protein binding negative regulation of glycolytic process negative regulation of glycolytic process negative regulation of Ras protein signal transduction metal ion binding monosaccharide binding extracellular exosome cellular response to magnesium ion |
| Ontology : EGO-EBI | negative regulation of transcription by RNA polymerase II RNA polymerase II transcription factor binding protein binding nucleus cytoplasm cytoplasm cytosol cytosol cytosol sucrose biosynthetic process fructose metabolic process fructose 6-phosphate metabolic process fructose 6-phosphate metabolic process gluconeogenesis gluconeogenesis gluconeogenesis gluconeogenesis gluconeogenesis regulation of gluconeogenesis AMP binding dephosphorylation dephosphorylation negative regulation of cell growth fructose 1,6-bisphosphate metabolic process cellular response to drug fructose 1,6-bisphosphate 1-phosphatase activity fructose 1,6-bisphosphate 1-phosphatase activity fructose 1,6-bisphosphate 1-phosphatase activity identical protein binding negative regulation of glycolytic process negative regulation of glycolytic process negative regulation of Ras protein signal transduction metal ion binding monosaccharide binding extracellular exosome cellular response to magnesium ion |
| Pathways : KEGG | Glycolysis / Gluconeogenesis Pentose phosphate pathway Fructose and mannose metabolism Insulin signaling pathway |
| NDEx Network | FBP1 |
| Atlas of Cancer Signalling Network | FBP1 |
| Wikipedia pathways | FBP1 |
| Orthology - Evolution |
|---|
| OrthoDB | 2203 |
| GeneTree (enSembl) | ENSG00000165140 |
| Phylogenetic Trees/Animal Genes : TreeFam | FBP1 |
| HOGENOM | P09467 |
| Homologs : HomoloGene | FBP1 |
| Homology/Alignments : Family Browser (UCSC) | FBP1 |
| Gene fusions - Rearrangements |
|---|
| Fusion : Quiver | FBP1 |
| Polymorphisms : SNP and Copy number variants |
|---|
| NCBI Variation Viewer | FBP1 [hg38] |
| dbVar | FBP1 |
| ClinVar | FBP1 |
| Monarch | FBP1 |
| 1000_Genomes | FBP1 |
| Exome Variant Server | FBP1 |
| GNOMAD Browser | ENSG00000165140 |
| Varsome Browser | FBP1 |
| Genomic Variants (DGV) | FBP1 [DGVbeta] |
| DECIPHER | FBP1 [patients] [syndromes] [variants] [genes] |
| CONAN: Copy Number Analysis | FBP1 |
| Mutations |
|---|
| ICGC Data Portal | FBP1 |
| TCGA Data Portal | FBP1 |
| Broad Tumor Portal | FBP1 |
| OASIS Portal | FBP1 [ Somatic mutations - Copy number] |
| Somatic Mutations in Cancer : COSMIC | FBP1 [overview] [genome browser] [tissue] [distribution] |
| Somatic Mutations in Cancer : COSMIC3D | FBP1 |
| Mutations and Diseases : HGMD | FBP1 |
| LOVD (Leiden Open Variation Database) | Whole genome datasets |
| LOVD (Leiden Open Variation Database) | LOVD - Leiden Open Variation Database |
| LOVD (Leiden Open Variation Database) | LOVD 3.0 shared installation |
| LOVD (Leiden Open Variation Database) | MSeqDR-LSDB Mitochondrial Disease Locus Specific Database |
| BioMuta | search FBP1 |
| DgiDB (Drug Gene Interaction Database) | FBP1 |
| DoCM (Curated mutations) | FBP1 (select the gene name) |
| CIViC (Clinical Interpretations of Variants in Cancer) | FBP1 (select a term) |
| intoGen | FBP1 |
| Cancer3D | FBP1(select the gene name) |
| Impact of mutations | [PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser] |
| Diseases |
|---|
| OMIM | 229700 611570 |
| Orphanet | 676 |
| DisGeNET | FBP1 |
| Medgen | FBP1 |
| Genetic Testing Registry | FBP1
|
| NextProt | P09467 [Medical] |
| GENETests | FBP1 |
| Target Validation | FBP1 |
| Huge Navigator |
FBP1 [HugePedia] |
| ClinGen | FBP1 |
| Clinical trials, drugs, therapy |
|---|
| MyCancerGenome | FBP1 |
| Protein Interactions : CTD | |
| Pharm GKB Gene | PA28018 |
| Pharos | P09467 |
| Clinical trial | FBP1 |
| Miscellaneous |
|---|
| canSAR (ICR) | FBP1 (select the gene name) |
| Harmonizome | FBP1 |
| DataMed Index | FBP1 |
| Probes |
|---|
| Litterature |
|---|
| PubMed | 112 Pubmed reference(s) in Entrez |
| GeneRIFs | Gene References Into Functions (Entrez) |
| EVEX | FBP1 |
