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FBP2 (fructose-bisphosphatase 2)

Identity

Alias_namesfructose-1
Other alias-
HGNC (Hugo) FBP2
LocusID (NCBI) 8789
Atlas_Id 47210
Location 9q22.32  [Link to chromosome band 9q22]
Location_base_pair Starts at 94558714 and ends at 94593832 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
PRKAB2 (1q21.1) / FBP2 (9q22.32)PRKAB2 1q21.1 / FBP2 9q22.32

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)FBP2   3607
Cards
Entrez_Gene (NCBI)FBP2  8789  fructose-bisphosphatase 2
Aliases
GeneCards (Weizmann)FBP2
Ensembl hg19 (Hinxton)ENSG00000130957 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000130957 [Gene_View]  chr9:94558714-94593832 [Contig_View]  FBP2 [Vega]
ICGC DataPortalENSG00000130957
TCGA cBioPortalFBP2
AceView (NCBI)FBP2
Genatlas (Paris)FBP2
WikiGenes8789
SOURCE (Princeton)FBP2
Genetics Home Reference (NIH)FBP2
Genomic and cartography
GoldenPath hg38 (UCSC)FBP2  -     chr9:94558714-94593832 -  9q22.32   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)FBP2  -     9q22.32   [Description]    (hg19-Feb_2009)
EnsemblFBP2 - 9q22.32 [CytoView hg19]  FBP2 - 9q22.32 [CytoView hg38]
Mapping of homologs : NCBIFBP2 [Mapview hg19]  FBP2 [Mapview hg38]
OMIM603027   
Gene and transcription
Genbank (Entrez)AJ573829 BC113632 BC117477 BM686555 BU727940
RefSeq transcript (Entrez)NM_003837
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)FBP2
Cluster EST : UnigeneHs.61255 [ NCBI ]
CGAP (NCI)Hs.61255
Alternative Splicing GalleryENSG00000130957
Gene ExpressionFBP2 [ NCBI-GEO ]   FBP2 [ EBI - ARRAY_EXPRESS ]   FBP2 [ SEEK ]   FBP2 [ MEM ]
Gene Expression Viewer (FireBrowse)FBP2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)8789
GTEX Portal (Tissue expression)FBP2
Protein : pattern, domain, 3D structure
UniProt/SwissProtO00757   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO00757  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO00757
Splice isoforms : SwissVarO00757
Catalytic activity : Enzyme3.1.3.11 [ Enzyme-Expasy ]   3.1.3.113.1.3.11 [ IntEnz-EBI ]   3.1.3.11 [ BRENDA ]   3.1.3.11 [ KEGG ]   
PhosPhoSitePlusO00757
Domaine pattern : Prosite (Expaxy)FBPASE (PS00124)   
Domains : Interpro (EBI)FBPase_class-1    FBPase_N    FBPtase    Fructose_bisphosphatase_AS   
Domain families : Pfam (Sanger)FBPase (PF00316)   
Domain families : Pfam (NCBI)pfam00316   
Conserved Domain (NCBI)FBP2
DMDM Disease mutations8789
Blocks (Seattle)FBP2
PDB (SRS)3IFA    3IFC    4HE0    4HE1    4HE2    5ET5    5ET6    5ET7    5ET8   
PDB (PDBSum)3IFA    3IFC    4HE0    4HE1    4HE2    5ET5    5ET6    5ET7    5ET8   
PDB (IMB)3IFA    3IFC    4HE0    4HE1    4HE2    5ET5    5ET6    5ET7    5ET8   
PDB (RSDB)3IFA    3IFC    4HE0    4HE1    4HE2    5ET5    5ET6    5ET7    5ET8   
Structural Biology KnowledgeBase3IFA    3IFC    4HE0    4HE1    4HE2    5ET5    5ET6    5ET7    5ET8   
SCOP (Structural Classification of Proteins)3IFA    3IFC    4HE0    4HE1    4HE2    5ET5    5ET6    5ET7    5ET8   
CATH (Classification of proteins structures)3IFA    3IFC    4HE0    4HE1    4HE2    5ET5    5ET6    5ET7    5ET8   
SuperfamilyO00757
Human Protein AtlasENSG00000130957
Peptide AtlasO00757
HPRD04322
IPIIPI00299456   
Protein Interaction databases
DIP (DOE-UCLA)O00757
IntAct (EBI)O00757
FunCoupENSG00000130957
BioGRIDFBP2
STRING (EMBL)FBP2
ZODIACFBP2
Ontologies - Pathways
QuickGOO00757
Ontology : AmiGOprotein binding  nucleoplasm  cytosol  cytosol  plasma membrane  sucrose biosynthetic process  fructose metabolic process  fructose 6-phosphate metabolic process  gluconeogenesis  gluconeogenesis  gluconeogenesis  dephosphorylation  Z disc  cell junction  fructose 1,6-bisphosphate metabolic process  fructose 1,6-bisphosphate 1-phosphatase activity  fructose 1,6-bisphosphate 1-phosphatase activity  identical protein binding  metal ion binding  extracellular exosome  
Ontology : EGO-EBIprotein binding  nucleoplasm  cytosol  cytosol  plasma membrane  sucrose biosynthetic process  fructose metabolic process  fructose 6-phosphate metabolic process  gluconeogenesis  gluconeogenesis  gluconeogenesis  dephosphorylation  Z disc  cell junction  fructose 1,6-bisphosphate metabolic process  fructose 1,6-bisphosphate 1-phosphatase activity  fructose 1,6-bisphosphate 1-phosphatase activity  identical protein binding  metal ion binding  extracellular exosome  
Pathways : KEGGGlycolysis / Gluconeogenesis    Pentose phosphate pathway    Fructose and mannose metabolism    Insulin signaling pathway   
NDEx NetworkFBP2
Atlas of Cancer Signalling NetworkFBP2
Wikipedia pathwaysFBP2
Orthology - Evolution
OrthoDB8789
GeneTree (enSembl)ENSG00000130957
Phylogenetic Trees/Animal Genes : TreeFamFBP2
HOVERGENO00757
HOGENOMO00757
Homologs : HomoloGeneFBP2
Homology/Alignments : Family Browser (UCSC)FBP2
Gene fusions - Rearrangements
Fusion : MitelmanPRKAB2/FBP2 [1q21.1/9q22.32]  [t(1;9)(q21;q22)]  
Fusion: TCGAPRKAB2 1q21.1 FBP2 9q22.32 KIRC
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerFBP2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)FBP2
dbVarFBP2
ClinVarFBP2
1000_GenomesFBP2 
Exome Variant ServerFBP2
ExAC (Exome Aggregation Consortium)FBP2 (select the gene name)
Genetic variants : HAPMAP8789
Genomic Variants (DGV)FBP2 [DGVbeta]
DECIPHERFBP2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisFBP2 
Mutations
ICGC Data PortalFBP2 
TCGA Data PortalFBP2 
Broad Tumor PortalFBP2
OASIS PortalFBP2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICFBP2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDFBP2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch FBP2
DgiDB (Drug Gene Interaction Database)FBP2
DoCM (Curated mutations)FBP2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)FBP2 (select a term)
intoGenFBP2
Cancer3DFBP2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603027   
Orphanet
MedgenFBP2
Genetic Testing Registry FBP2
NextProtO00757 [Medical]
TSGene8789
GENETestsFBP2
Target ValidationFBP2
Huge Navigator FBP2 [HugePedia]
snp3D : Map Gene to Disease8789
BioCentury BCIQFBP2
ClinGenFBP2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD8789
Chemical/Pharm GKB GenePA28019
Clinical trialFBP2
Miscellaneous
canSAR (ICR)FBP2 (select the gene name)
Probes
Litterature
PubMed18 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineFBP2
EVEXFBP2
GoPubMedFBP2
iHOPFBP2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 19:07:59 CEST 2017

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