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FBRSL1 (fibrosin like 1)

Identity

Alias (NCBI)-
HGNC (Hugo) FBRSL1
HGNC Alias symbKIAA1545
HGNC Previous namefibrosin-like 1
LocusID (NCBI) 57666
Atlas_Id 63311
Location 12q24.33  [Link to chromosome band 12q24]
Location_base_pair Starts at 132490571 and ends at 132585187 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ARFGAP2 (11p11.2) / FBRSL1 (12q24.33)ERCC1 (19q13.32) / FBRSL1 (12q24.33)FBRSL1 (12q24.33) / CKAP4 (12q23.3)
FBRSL1 (12q24.33) / COL9A2 (1p34.2)FBRSL1 (12q24.33) / EP400 (12q24.33)FBRSL1 (12q24.33) / FAT1 (4q35.2)
FBRSL1 (12q24.33) / GALNT9 (12q24.33)FBRSL1 (12q24.33) / GNAO1 (16q12.2)FBRSL1 (12q24.33) / LIPF (10q23.31)
FBRSL1 (12q24.33) / MARS (12q13.3)FBRSL1 (12q24.33) / RBM42 (19q13.12)FBRSL1 (12q24.33) / STX2 (12q24.33)
FBRSL1 (12q24.33) / ZMPSTE24 (1p34.2)NOC4L (12q24.33) / FBRSL1 (12q24.33)FBRSL1 CKAP4
FBRSL1 GALNT9

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



Other Leukemias implicated (Data extracted from papers in the Atlas) [ 8 ]
  t(9;12)(p13;q24) FBRSL1/PAX5
t(9;12)(p13;q24) PAX5/FBRSL1
t(12;12)(q24;q24) NOC4L/FBRSL1
t(12;12)(q24;q24) POLE/FBRSL1
t(9;12)(p13;q24) FBRSL1/PAX5
t(9;12)(p13;q24) PAX5/FBRSL1
t(12;12)(q24;q24) NOC4L/FBRSL1
t(12;12)(q24;q24) POLE/FBRSL1


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 3 ]
  t(11;12)(p11;q24) ARFGAP2/FBRSL1
t(12;12)(q23;q24) FBRSL1/CKAP4
FBRSL1/GALNT9 (12q24)


External links

Nomenclature
HGNC (Hugo)FBRSL1   29308
Cards
Entrez_Gene (NCBI)FBRSL1    fibrosin like 1
Aliases
GeneCards (Weizmann)FBRSL1
Ensembl hg19 (Hinxton)ENSG00000112787 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000112787 [Gene_View]  ENSG00000112787 [Sequence]  chr12:132490571-132585187 [Contig_View]  FBRSL1 [Vega]
ICGC DataPortalENSG00000112787
TCGA cBioPortalFBRSL1
AceView (NCBI)FBRSL1
Genatlas (Paris)FBRSL1
SOURCE (Princeton)FBRSL1
Genetics Home Reference (NIH)FBRSL1
Genomic and cartography
GoldenPath hg38 (UCSC)FBRSL1  -     chr12:132490571-132585187 +  12q24.33   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)FBRSL1  -     12q24.33   [Description]    (hg19-Feb_2009)
GoldenPathFBRSL1 - 12q24.33 [CytoView hg19]  FBRSL1 - 12q24.33 [CytoView hg38]
ImmunoBaseENSG00000112787
genome Data Viewer NCBIFBRSL1 [Mapview hg19]  
Gene and transcription
Genbank (Entrez)AB046765 AF490258 BC008052 BC013284 BC034807
RefSeq transcript (Entrez)NM_001142641 NM_001367871
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)FBRSL1
Alternative Splicing GalleryENSG00000112787
Gene ExpressionFBRSL1 [ NCBI-GEO ]   FBRSL1 [ EBI - ARRAY_EXPRESS ]   FBRSL1 [ SEEK ]   FBRSL1 [ MEM ]
Gene Expression Viewer (FireBrowse)FBRSL1 [ Firebrowse - Broad ]
GenevisibleExpression of FBRSL1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)57666
GTEX Portal (Tissue expression)FBRSL1
Human Protein AtlasENSG00000112787-FBRSL1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9HCM7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9HCM7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9HCM7
Splice isoforms : SwissVarQ9HCM7
PhosPhoSitePlusQ9HCM7
Domains : Interpro (EBI)AUTS2   
Domain families : Pfam (Sanger)Auts2 (PF15336)   
Domain families : Pfam (NCBI)pfam15336   
Conserved Domain (NCBI)FBRSL1
Blocks (Seattle)FBRSL1
SuperfamilyQ9HCM7
Human Protein Atlas [tissue]ENSG00000112787-FBRSL1 [tissue]
Peptide AtlasQ9HCM7
IPIIPI00941159   IPI00411412   IPI00973550   
Protein Interaction databases
DIP (DOE-UCLA)Q9HCM7
IntAct (EBI)Q9HCM7
BioGRIDFBRSL1
STRING (EMBL)FBRSL1
ZODIACFBRSL1
Ontologies - Pathways
QuickGOQ9HCM7
Ontology : AmiGORNA binding  
Ontology : EGO-EBIRNA binding  
NDEx NetworkFBRSL1
Atlas of Cancer Signalling NetworkFBRSL1
Wikipedia pathwaysFBRSL1
Orthology - Evolution
OrthoDB57666
GeneTree (enSembl)ENSG00000112787
Phylogenetic Trees/Animal Genes : TreeFamFBRSL1
HOGENOMQ9HCM7
Homologs : HomoloGeneFBRSL1
Homology/Alignments : Family Browser (UCSC)FBRSL1
Gene fusions - Rearrangements
Fusion PortalFBRSL1 CKAP4
Fusion PortalFBRSL1 GALNT9
Fusion : QuiverFBRSL1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerFBRSL1 [hg38]
dbVarFBRSL1
ClinVarFBRSL1
MonarchFBRSL1
1000_GenomesFBRSL1 
Exome Variant ServerFBRSL1
GNOMAD BrowserENSG00000112787
Varsome BrowserFBRSL1
Genomic Variants (DGV)FBRSL1 [DGVbeta]
DECIPHERFBRSL1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisFBRSL1 
Mutations
ICGC Data PortalFBRSL1 
TCGA Data PortalFBRSL1 
Broad Tumor PortalFBRSL1
OASIS PortalFBRSL1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICFBRSL1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DFBRSL1
Mutations and Diseases : HGMDFBRSL1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch FBRSL1
DgiDB (Drug Gene Interaction Database)FBRSL1
DoCM (Curated mutations)FBRSL1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)FBRSL1 (select a term)
intoGenFBRSL1
Cancer3DFBRSL1(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETFBRSL1
MedgenFBRSL1
Genetic Testing Registry FBRSL1
NextProtQ9HCM7 [Medical]
GENETestsFBRSL1
Target ValidationFBRSL1
Huge Navigator FBRSL1 [HugePedia]
ClinGenFBRSL1
Clinical trials, drugs, therapy
MyCancerGenomeFBRSL1
Protein Interactions : CTD
Pharm GKB GenePA164720011
Clinical trialFBRSL1
Miscellaneous
canSAR (ICR)FBRSL1 (select the gene name)
HarmonizomeFBRSL1
DataMed IndexFBRSL1
Probes
Litterature
PubMed14 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineFBRSL1
EVEXFBRSL1
GoPubMedFBRSL1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Sat Dec 5 16:54:26 CET 2020

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