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FBXL12 (F-box and leucine-rich repeat protein 12)

Identity

Alias_symbol (synonym)FLJ20188
Fbl12
Other alias
HGNC (Hugo) FBXL12
LocusID (NCBI) 54850
Atlas_Id 46954
Location 19p13.2  [Link to chromosome band 19p13]
Location_base_pair Starts at 9920943 and ends at 9929779 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)FBXL12   13611
Cards
Entrez_Gene (NCBI)FBXL12  54850  F-box and leucine-rich repeat protein 12
AliasesFbl12
GeneCards (Weizmann)FBXL12
Ensembl hg19 (Hinxton)ENSG00000127452 [Gene_View]  chr19:9920943-9929779 [Contig_View]  FBXL12 [Vega]
Ensembl hg38 (Hinxton)ENSG00000127452 [Gene_View]  chr19:9920943-9929779 [Contig_View]  FBXL12 [Vega]
ICGC DataPortalENSG00000127452
TCGA cBioPortalFBXL12
AceView (NCBI)FBXL12
Genatlas (Paris)FBXL12
WikiGenes54850
SOURCE (Princeton)FBXL12
Genetics Home Reference (NIH)FBXL12
Genomic and cartography
GoldenPath hg19 (UCSC)FBXL12  -     chr19:9920943-9929779 -  19p13.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)FBXL12  -     19p13.2   [Description]    (hg38-Dec_2013)
EnsemblFBXL12 - 19p13.2 [CytoView hg19]  FBXL12 - 19p13.2 [CytoView hg38]
Mapping of homologs : NCBIFBXL12 [Mapview hg19]  FBXL12 [Mapview hg38]
OMIM609079   
Gene and transcription
Genbank (Entrez)AA524458 AK000195 AK027004 AK093760 AL389936
RefSeq transcript (Entrez)NM_001316936 NM_001316937 NM_001316938 NM_001316939 NM_001316940 NM_001316941 NM_001316942 NM_017703
RefSeq genomic (Entrez)NC_000019 NC_018930 NT_011295 NW_004929414
Consensus coding sequences : CCDS (NCBI)FBXL12
Cluster EST : UnigeneHs.12439 [ NCBI ]
CGAP (NCI)Hs.12439
Alternative Splicing GalleryENSG00000127452
Gene ExpressionFBXL12 [ NCBI-GEO ]   FBXL12 [ EBI - ARRAY_EXPRESS ]   FBXL12 [ SEEK ]   FBXL12 [ MEM ]
Gene Expression Viewer (FireBrowse)FBXL12 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)54850
GTEX Portal (Tissue expression)FBXL12
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NXK8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NXK8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NXK8
Splice isoforms : SwissVarQ9NXK8
PhosPhoSitePlusQ9NXK8
Domaine pattern : Prosite (Expaxy)FBOX (PS50181)   
Domains : Interpro (EBI)F-box_dom    L_dom-like   
Domain families : Pfam (Sanger)F-box-like (PF12937)   
Domain families : Pfam (NCBI)pfam12937   
Domain families : Smart (EMBL)FBOX (SM00256)  
Conserved Domain (NCBI)FBXL12
DMDM Disease mutations54850
Blocks (Seattle)FBXL12
SuperfamilyQ9NXK8
Human Protein AtlasENSG00000127452
Peptide AtlasQ9NXK8
HPRD12363
IPIIPI00015011   IPI00394987   
Protein Interaction databases
DIP (DOE-UCLA)Q9NXK8
IntAct (EBI)Q9NXK8
FunCoupENSG00000127452
BioGRIDFBXL12
STRING (EMBL)FBXL12
ZODIACFBXL12
Ontologies - Pathways
QuickGOQ9NXK8
Ontology : AmiGOubiquitin ligase complex  protein binding  cytoplasm  ubiquitin-dependent protein catabolic process  protein ubiquitination  
Ontology : EGO-EBIubiquitin ligase complex  protein binding  cytoplasm  ubiquitin-dependent protein catabolic process  protein ubiquitination  
NDEx NetworkFBXL12
Atlas of Cancer Signalling NetworkFBXL12
Wikipedia pathwaysFBXL12
Orthology - Evolution
OrthoDB54850
GeneTree (enSembl)ENSG00000127452
Phylogenetic Trees/Animal Genes : TreeFamFBXL12
HOVERGENQ9NXK8
HOGENOMQ9NXK8
Homologs : HomoloGeneFBXL12
Homology/Alignments : Family Browser (UCSC)FBXL12
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerFBXL12 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)FBXL12
dbVarFBXL12
ClinVarFBXL12
1000_GenomesFBXL12 
Exome Variant ServerFBXL12
ExAC (Exome Aggregation Consortium)FBXL12 (select the gene name)
Genetic variants : HAPMAP54850
Genomic Variants (DGV)FBXL12 [DGVbeta]
DECIPHER (Syndromes)19:9920943-9929779  ENSG00000127452
CONAN: Copy Number AnalysisFBXL12 
Mutations
ICGC Data PortalFBXL12 
TCGA Data PortalFBXL12 
Broad Tumor PortalFBXL12
OASIS PortalFBXL12 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICFBXL12  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDFBXL12
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch FBXL12
DgiDB (Drug Gene Interaction Database)FBXL12
DoCM (Curated mutations)FBXL12 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)FBXL12 (select a term)
intoGenFBXL12
Cancer3DFBXL12(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609079   
Orphanet
MedgenFBXL12
Genetic Testing Registry FBXL12
NextProtQ9NXK8 [Medical]
TSGene54850
GENETestsFBXL12
Huge Navigator FBXL12 [HugePedia]
snp3D : Map Gene to Disease54850
BioCentury BCIQFBXL12
ClinGenFBXL12
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD54850
Chemical/Pharm GKB GenePA134934043
Clinical trialFBXL12
Miscellaneous
canSAR (ICR)FBXL12 (select the gene name)
Probes
Litterature
PubMed18 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineFBXL12
EVEXFBXL12
GoPubMedFBXL12
iHOPFBXL12
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 30 15:00:55 CEST 2017

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