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FBXL18 (F-box and leucine rich repeat protein 18)

Identity

Alias_symbol (synonym)FLJ11467
Fbl18
Other alias
HGNC (Hugo) FBXL18
LocusID (NCBI) 80028
Atlas_Id 52999
Location 7p22.1  [Link to chromosome band 7p22]
Location_base_pair Starts at 5489178 and ends at 5513798 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
FBXL18 (7p22.1) / ARPC4-TTLL3 (3p25.3)FBXL18 (7p22.1) / CHRM3 (1q43)FBXL18 (7p22.1) / FBXL18 (7p22.1)
FBXL18 (7p22.1) / RNF216 (7p22.1)FBXL18 (7p22.1) / TXNDC5 (6p24.3)FBXL18 7p22.1 / RNF216 7p22.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)FBXL18   21874
Cards
Entrez_Gene (NCBI)FBXL18  80028  F-box and leucine rich repeat protein 18
AliasesFbl18
GeneCards (Weizmann)FBXL18
Ensembl hg19 (Hinxton)ENSG00000155034 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000155034 [Gene_View]  chr7:5489178-5513798 [Contig_View]  FBXL18 [Vega]
ICGC DataPortalENSG00000155034
TCGA cBioPortalFBXL18
AceView (NCBI)FBXL18
Genatlas (Paris)FBXL18
WikiGenes80028
SOURCE (Princeton)FBXL18
Genetics Home Reference (NIH)FBXL18
Genomic and cartography
GoldenPath hg38 (UCSC)FBXL18  -     chr7:5489178-5513798 -  7p22.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)FBXL18  -     7p22.1   [Description]    (hg19-Feb_2009)
EnsemblFBXL18 - 7p22.1 [CytoView hg19]  FBXL18 - 7p22.1 [CytoView hg38]
Mapping of homologs : NCBIFBXL18 [Mapview hg19]  FBXL18 [Mapview hg38]
OMIM609084   
Gene and transcription
Genbank (Entrez)AA878073 AK001638 AK021529 AK057042 AK095394
RefSeq transcript (Entrez)NM_001321213 NM_024963
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)FBXL18
Cluster EST : UnigeneHs.706587 [ NCBI ]
CGAP (NCI)Hs.706587
Alternative Splicing GalleryENSG00000155034
Gene ExpressionFBXL18 [ NCBI-GEO ]   FBXL18 [ EBI - ARRAY_EXPRESS ]   FBXL18 [ SEEK ]   FBXL18 [ MEM ]
Gene Expression Viewer (FireBrowse)FBXL18 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)80028
GTEX Portal (Tissue expression)FBXL18
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96ME1   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96ME1  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96ME1
Splice isoforms : SwissVarQ96ME1
PhosPhoSitePlusQ96ME1
Domaine pattern : Prosite (Expaxy)FBOX (PS50181)   
Domains : Interpro (EBI)F-box_dom    L_dom-like   
Domain families : Pfam (Sanger)F-box (PF00646)   
Domain families : Pfam (NCBI)pfam00646   
Conserved Domain (NCBI)FBXL18
DMDM Disease mutations80028
Blocks (Seattle)FBXL18
SuperfamilyQ96ME1
Human Protein AtlasENSG00000155034
Peptide AtlasQ96ME1
HPRD07753
IPIIPI00329057   IPI00336170   IPI00552588   IPI00386731   IPI01009232   IPI00419171   IPI00060572   IPI00977849   
Protein Interaction databases
DIP (DOE-UCLA)Q96ME1
IntAct (EBI)Q96ME1
FunCoupENSG00000155034
BioGRIDFBXL18
STRING (EMBL)FBXL18
ZODIACFBXL18
Ontologies - Pathways
QuickGOQ96ME1
Ontology : AmiGOprotein polyubiquitination  ubiquitin-protein transferase activity  ubiquitin-protein transferase activity  cytosol  SCF-dependent proteasomal ubiquitin-dependent protein catabolic process  
Ontology : EGO-EBIprotein polyubiquitination  ubiquitin-protein transferase activity  ubiquitin-protein transferase activity  cytosol  SCF-dependent proteasomal ubiquitin-dependent protein catabolic process  
NDEx NetworkFBXL18
Atlas of Cancer Signalling NetworkFBXL18
Wikipedia pathwaysFBXL18
Orthology - Evolution
OrthoDB80028
GeneTree (enSembl)ENSG00000155034
Phylogenetic Trees/Animal Genes : TreeFamFBXL18
HOVERGENQ96ME1
HOGENOMQ96ME1
Homologs : HomoloGeneFBXL18
Homology/Alignments : Family Browser (UCSC)FBXL18
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerFBXL18 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)FBXL18
dbVarFBXL18
ClinVarFBXL18
1000_GenomesFBXL18 
Exome Variant ServerFBXL18
ExAC (Exome Aggregation Consortium)FBXL18 (select the gene name)
Genetic variants : HAPMAP80028
Genomic Variants (DGV)FBXL18 [DGVbeta]
DECIPHERFBXL18 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisFBXL18 
Mutations
ICGC Data PortalFBXL18 
TCGA Data PortalFBXL18 
Broad Tumor PortalFBXL18
OASIS PortalFBXL18 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICFBXL18  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDFBXL18
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch FBXL18
DgiDB (Drug Gene Interaction Database)FBXL18
DoCM (Curated mutations)FBXL18 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)FBXL18 (select a term)
intoGenFBXL18
Cancer3DFBXL18(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609084   
Orphanet
MedgenFBXL18
Genetic Testing Registry FBXL18
NextProtQ96ME1 [Medical]
TSGene80028
GENETestsFBXL18
Huge Navigator FBXL18 [HugePedia]
snp3D : Map Gene to Disease80028
BioCentury BCIQFBXL18
ClinGenFBXL18
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD80028
Chemical/Pharm GKB GenePA134949446
Clinical trialFBXL18
Miscellaneous
canSAR (ICR)FBXL18 (select the gene name)
Probes
Litterature
PubMed19 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineFBXL18
EVEXFBXL18
GoPubMedFBXL18
iHOPFBXL18
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri May 19 12:15:37 CEST 2017

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