Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

FBXL6 (F-box and leucine rich repeat protein 6)

Identity

Alias_symbol (synonym)FBL6
Other aliasFBL6A
PP14630
HGNC (Hugo) FBXL6
LocusID (NCBI) 26233
Atlas_Id 63319
Location 8q24.3  [Link to chromosome band 8q24]
Location_base_pair Starts at 144355428 and ends at 144358523 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)FBXL6   13603
Cards
Entrez_Gene (NCBI)FBXL6  26233  F-box and leucine rich repeat protein 6
AliasesFBL6; FBL6A; PP14630
GeneCards (Weizmann)FBXL6
Ensembl hg19 (Hinxton)ENSG00000182325 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000182325 [Gene_View]  chr8:144355428-144358523 [Contig_View]  FBXL6 [Vega]
ICGC DataPortalENSG00000182325
TCGA cBioPortalFBXL6
AceView (NCBI)FBXL6
Genatlas (Paris)FBXL6
WikiGenes26233
SOURCE (Princeton)FBXL6
Genetics Home Reference (NIH)FBXL6
Genomic and cartography
GoldenPath hg38 (UCSC)FBXL6  -     chr8:144355428-144358523 -  8q24.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)FBXL6  -     8q24.3   [Description]    (hg19-Feb_2009)
EnsemblFBXL6 - 8q24.3 [CytoView hg19]  FBXL6 - 8q24.3 [CytoView hg38]
Mapping of homologs : NCBIFBXL6 [Mapview hg19]  FBXL6 [Mapview hg38]
OMIM609076   
Gene and transcription
Genbank (Entrez)AF174592 AF370422 AK026541 AK223088 AL713783
RefSeq transcript (Entrez)NM_012162 NM_024555
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)FBXL6
Cluster EST : UnigeneHs.12271 [ NCBI ]
CGAP (NCI)Hs.12271
Alternative Splicing GalleryENSG00000182325
Gene ExpressionFBXL6 [ NCBI-GEO ]   FBXL6 [ EBI - ARRAY_EXPRESS ]   FBXL6 [ SEEK ]   FBXL6 [ MEM ]
Gene Expression Viewer (FireBrowse)FBXL6 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)26233
GTEX Portal (Tissue expression)FBXL6
Human Protein AtlasENSG00000182325-FBXL6 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8N531   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8N531  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8N531
Splice isoforms : SwissVarQ8N531
PhosPhoSitePlusQ8N531
Domains : Interpro (EBI)F-box_dom    L_dom-like    Leu-rich_rpt    Leu-rich_rpt_Cys-con_subtyp   
Domain families : Pfam (Sanger)F-box-like (PF12937)    LRR_6 (PF13516)   
Domain families : Pfam (NCBI)pfam12937    pfam13516   
Domain families : Smart (EMBL)LRR_CC (SM00367)  
Conserved Domain (NCBI)FBXL6
DMDM Disease mutations26233
Blocks (Seattle)FBXL6
SuperfamilyQ8N531
Human Protein Atlas [tissue]ENSG00000182325-FBXL6 [tissue]
Peptide AtlasQ8N531
HPRD16429
IPIIPI00166767   IPI00377163   
Protein Interaction databases
DIP (DOE-UCLA)Q8N531
IntAct (EBI)Q8N531
FunCoupENSG00000182325
BioGRIDFBXL6
STRING (EMBL)FBXL6
ZODIACFBXL6
Ontologies - Pathways
QuickGOQ8N531
Ontology : AmiGOubiquitin-protein transferase activity  proteolysis  protein ubiquitination  
Ontology : EGO-EBIubiquitin-protein transferase activity  proteolysis  protein ubiquitination  
NDEx NetworkFBXL6
Atlas of Cancer Signalling NetworkFBXL6
Wikipedia pathwaysFBXL6
Orthology - Evolution
OrthoDB26233
GeneTree (enSembl)ENSG00000182325
Phylogenetic Trees/Animal Genes : TreeFamFBXL6
HOVERGENQ8N531
HOGENOMQ8N531
Homologs : HomoloGeneFBXL6
Homology/Alignments : Family Browser (UCSC)FBXL6
Gene fusions - Rearrangements
Tumor Fusion PortalFBXL6
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerFBXL6 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)FBXL6
dbVarFBXL6
ClinVarFBXL6
1000_GenomesFBXL6 
Exome Variant ServerFBXL6
ExAC (Exome Aggregation Consortium)ENSG00000182325
GNOMAD BrowserENSG00000182325
Genetic variants : HAPMAP26233
Genomic Variants (DGV)FBXL6 [DGVbeta]
DECIPHERFBXL6 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisFBXL6 
Mutations
ICGC Data PortalFBXL6 
TCGA Data PortalFBXL6 
Broad Tumor PortalFBXL6
OASIS PortalFBXL6 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICFBXL6  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDFBXL6
BioMutasearch FBXL6
DgiDB (Drug Gene Interaction Database)FBXL6
DoCM (Curated mutations)FBXL6 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)FBXL6 (select a term)
intoGenFBXL6
Cancer3DFBXL6(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609076   
Orphanet
DisGeNETFBXL6
MedgenFBXL6
Genetic Testing Registry FBXL6
NextProtQ8N531 [Medical]
TSGene26233
GENETestsFBXL6
Target ValidationFBXL6
Huge Navigator FBXL6 [HugePedia]
snp3D : Map Gene to Disease26233
BioCentury BCIQFBXL6
ClinGenFBXL6
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD26233
Chemical/Pharm GKB GenePA28026
Clinical trialFBXL6
Miscellaneous
canSAR (ICR)FBXL6 (select the gene name)
Probes
Litterature
PubMed13 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineFBXL6
EVEXFBXL6
GoPubMedFBXL6
iHOPFBXL6
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 13:18:11 CET 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.