FBXO16 (F-box protein 16)

2019-04-01 Affiliation

Identity

HGNC

FBXO16

LOCATION

8p21.1

LOCUSID

157574

ALIAS

FBX16

FUSION GENES

Show Gene Fusions

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 157574
MIM: 608519
HGNC: 13618
Ensembl: ENSG00000214050

Variants:

dbSNP: 157574
ClinVar: 157574
TCGA: ENSG00000214050
COSMIC: FBXO16

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000214050	ENST00000346498	J3KNU2
ENSG00000214050	ENST00000380254	Q8IX29
ENSG00000214050	ENST00000517673	E5RIL5
ENSG00000214050	ENST00000518248	H0YC72
ENSG00000214050	ENST00000518734	Q8IX29
ENSG00000214050	ENST00000519471	G3V0Z8
ENSG00000214050	ENST00000521548	E5RFF8

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Protein levels (Protein atlas)

Not detected

Low

Medium

High

cerebral cortex

cerebellum

hippocampus

caudate

thyroid gland

parathyroid gland

adrenal gland

pituitary gland

nasopharynx

bronchus

lung

oral mucosa

salivary gland

esophagus

stomach 1

stomach 2

duodenum

small intestine

colon

rectum

liver

gallbladder

pancreas

kidney

urinary bladder

testis

epididymis

seminal vesicle

prostate

vagina

ovary

fallopian tube

endometrium 1

endometrium 2

cervix, uterine

placenta

breast

heart muscle

smooth muscle

skeletal muscle

soft tissue 1

soft tissue 2

adipose tissue

skin 1

skin 2

appendix

spleen

lymph node

tonsil

bone marrow

References

Pubmed ID	Year	Title	Citations
30530053	2019	Attenuation of Tumor Suppressive Function of FBXO16 Ubiquitin Ligase Activates Wnt Signaling In Glioblastoma.	2
12243353	2002	cDNA cloning and expression analysis of a novel human F-box only protein.	1
30714168	2019	F-box protein FBXO16 functions as a tumor suppressor by attenuating nuclear β-catenin function.	1

Citation

Dessen P

FBXO16 (F-box protein 16)

Atlas Genet Cytogenet Oncol Haematol. 2019-04-01

Online version: http://atlasgeneticsoncology.org/gene/57820/fbxo16