Atlas of Genetics and Cytogenetics in Oncology and Haematology


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FBXO21 (F-box protein 21)

Identity

Alias_namesF-box only protein 21
Alias_symbol (synonym)FBX21
KIAA0875
Other alias
HGNC (Hugo) FBXO21
LocusID (NCBI) 23014
Atlas_Id 63325
Location 12q24.22  [Link to chromosome band 12q24]
Location_base_pair Starts at 117143780 and ends at 117190495 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
ACACB (12q24.11) / FBXO21 (12q24.22)RNF10 (12q24.31) / FBXO21 (12q24.22)STAMBPL1 (10q23.31) / FBXO21 (12q24.22)
TESC (12q24.22) / FBXO21 (12q24.22)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)FBXO21   13592
Cards
Entrez_Gene (NCBI)FBXO21  23014  F-box protein 21
AliasesFBX21
GeneCards (Weizmann)FBXO21
Ensembl hg19 (Hinxton)ENSG00000135108 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000135108 [Gene_View]  chr12:117143780-117190495 [Contig_View]  FBXO21 [Vega]
ICGC DataPortalENSG00000135108
TCGA cBioPortalFBXO21
AceView (NCBI)FBXO21
Genatlas (Paris)FBXO21
WikiGenes23014
SOURCE (Princeton)FBXO21
Genetics Home Reference (NIH)FBXO21
Genomic and cartography
GoldenPath hg38 (UCSC)FBXO21  -     chr12:117143780-117190495 -  12q24.22   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)FBXO21  -     12q24.22   [Description]    (hg19-Feb_2009)
EnsemblFBXO21 - 12q24.22 [CytoView hg19]  FBXO21 - 12q24.22 [CytoView hg38]
Mapping of homologs : NCBIFBXO21 [Mapview hg19]  FBXO21 [Mapview hg38]
OMIM609095   
Gene and transcription
Genbank (Entrez)AB020682 AF174601 AK001699 AK074714 AK308141
RefSeq transcript (Entrez)NM_015002 NM_033624
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)FBXO21
Cluster EST : UnigeneHs.740376 [ NCBI ]
CGAP (NCI)Hs.740376
Alternative Splicing GalleryENSG00000135108
Gene ExpressionFBXO21 [ NCBI-GEO ]   FBXO21 [ EBI - ARRAY_EXPRESS ]   FBXO21 [ SEEK ]   FBXO21 [ MEM ]
Gene Expression Viewer (FireBrowse)FBXO21 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)23014
GTEX Portal (Tissue expression)FBXO21
Protein : pattern, domain, 3D structure
UniProt/SwissProtO94952   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO94952  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO94952
Splice isoforms : SwissVarO94952
PhosPhoSitePlusO94952
Domains : Interpro (EBI)F-box_dom    Hemimethylated_DNA-bd_dom    SirB1_N   
Domain families : Pfam (Sanger)Transglut_core2 (PF13369)    YccV-like (PF08755)   
Domain families : Pfam (NCBI)pfam13369    pfam08755   
Domain families : Smart (EMBL)YccV-like (SM00992)  
Conserved Domain (NCBI)FBXO21
DMDM Disease mutations23014
Blocks (Seattle)FBXO21
SuperfamilyO94952
Human Protein AtlasENSG00000135108
Peptide AtlasO94952
HPRD09948
IPIIPI00025647   IPI00069507   IPI00794860   IPI00216812   IPI01020930   IPI01021707   
Protein Interaction databases
DIP (DOE-UCLA)O94952
IntAct (EBI)O94952
FunCoupENSG00000135108
BioGRIDFBXO21
STRING (EMBL)FBXO21
ZODIACFBXO21
Ontologies - Pathways
QuickGOO94952
Ontology : AmiGOubiquitin ligase complex  protein polyubiquitination  DNA binding  ubiquitin-protein transferase activity  ubiquitin-protein transferase activity  ubiquitin-protein transferase activity  cytosol  ubiquitin-dependent protein catabolic process  
Ontology : EGO-EBIubiquitin ligase complex  protein polyubiquitination  DNA binding  ubiquitin-protein transferase activity  ubiquitin-protein transferase activity  ubiquitin-protein transferase activity  cytosol  ubiquitin-dependent protein catabolic process  
NDEx NetworkFBXO21
Atlas of Cancer Signalling NetworkFBXO21
Wikipedia pathwaysFBXO21
Orthology - Evolution
OrthoDB23014
GeneTree (enSembl)ENSG00000135108
Phylogenetic Trees/Animal Genes : TreeFamFBXO21
HOVERGENO94952
HOGENOMO94952
Homologs : HomoloGeneFBXO21
Homology/Alignments : Family Browser (UCSC)FBXO21
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerFBXO21 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)FBXO21
dbVarFBXO21
ClinVarFBXO21
1000_GenomesFBXO21 
Exome Variant ServerFBXO21
ExAC (Exome Aggregation Consortium)FBXO21 (select the gene name)
Genetic variants : HAPMAP23014
Genomic Variants (DGV)FBXO21 [DGVbeta]
DECIPHERFBXO21 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisFBXO21 
Mutations
ICGC Data PortalFBXO21 
TCGA Data PortalFBXO21 
Broad Tumor PortalFBXO21
OASIS PortalFBXO21 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICFBXO21  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDFBXO21
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch FBXO21
DgiDB (Drug Gene Interaction Database)FBXO21
DoCM (Curated mutations)FBXO21 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)FBXO21 (select a term)
intoGenFBXO21
Cancer3DFBXO21(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609095   
Orphanet
MedgenFBXO21
Genetic Testing Registry FBXO21
NextProtO94952 [Medical]
TSGene23014
GENETestsFBXO21
Target ValidationFBXO21
Huge Navigator FBXO21 [HugePedia]
snp3D : Map Gene to Disease23014
BioCentury BCIQFBXO21
ClinGenFBXO21
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD23014
Chemical/Pharm GKB GenePA28034
Clinical trialFBXO21
Miscellaneous
canSAR (ICR)FBXO21 (select the gene name)
Probes
Litterature
PubMed21 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineFBXO21
EVEXFBXO21
GoPubMedFBXO21
iHOPFBXO21
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Aug 1 16:15:19 CEST 2017

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