Atlas of Genetics and Cytogenetics in Oncology and Haematology


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FBXO22 (F-box protein 22)

Identity

Alias_namesF-box only protein 22
Alias_symbol (synonym)FBX22
FISTC1
Other alias
HGNC (Hugo) FBXO22
LocusID (NCBI) 26263
Atlas_Id 56035
Location 15q24.2  [Link to chromosome band 15q24]
Location_base_pair Starts at 75903859 and ends at 75930867 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
FBXO22 (15q24.2) / SNX33 (15q24.2)FBXO22 (15q24.2) / UBE2Q2 (15q24.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)FBXO22   13593
Cards
Entrez_Gene (NCBI)FBXO22  26263  F-box protein 22
AliasesFBX22; FISTC1
GeneCards (Weizmann)FBXO22
Ensembl hg19 (Hinxton)ENSG00000167196 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000167196 [Gene_View]  chr15:75903859-75930867 [Contig_View]  FBXO22 [Vega]
ICGC DataPortalENSG00000167196
TCGA cBioPortalFBXO22
AceView (NCBI)FBXO22
Genatlas (Paris)FBXO22
WikiGenes26263
SOURCE (Princeton)FBXO22
Genetics Home Reference (NIH)FBXO22
Genomic and cartography
GoldenPath hg38 (UCSC)FBXO22  -     chr15:75903859-75930867 +  15q24.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)FBXO22  -     15q24.2   [Description]    (hg19-Feb_2009)
EnsemblFBXO22 - 15q24.2 [CytoView hg19]  FBXO22 - 15q24.2 [CytoView hg38]
Mapping of homologs : NCBIFBXO22 [Mapview hg19]  FBXO22 [Mapview hg38]
OMIM609096   
Gene and transcription
Genbank (Entrez)AK024048 AK026282 AK223500 AK294311 AK307084
RefSeq transcript (Entrez)NM_012170 NM_147188
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)FBXO22
Cluster EST : UnigeneHs.591115 [ NCBI ]
CGAP (NCI)Hs.591115
Alternative Splicing GalleryENSG00000167196
Gene ExpressionFBXO22 [ NCBI-GEO ]   FBXO22 [ EBI - ARRAY_EXPRESS ]   FBXO22 [ SEEK ]   FBXO22 [ MEM ]
Gene Expression Viewer (FireBrowse)FBXO22 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)26263
GTEX Portal (Tissue expression)FBXO22
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8NEZ5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8NEZ5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8NEZ5
Splice isoforms : SwissVarQ8NEZ5
PhosPhoSitePlusQ8NEZ5
Domains : Interpro (EBI)F-box_dom    FIST_C   
Domain families : Pfam (Sanger)F-box (PF00646)    FIST_C (PF10442)   
Domain families : Pfam (NCBI)pfam00646    pfam10442   
Domain families : Smart (EMBL)FIST_C (SM01204)  
Conserved Domain (NCBI)FBXO22
DMDM Disease mutations26263
Blocks (Seattle)FBXO22
SuperfamilyQ8NEZ5
Human Protein AtlasENSG00000167196
Peptide AtlasQ8NEZ5
HPRD16437
IPIIPI00183208   IPI00554605   IPI00169168   IPI01025801   
Protein Interaction databases
DIP (DOE-UCLA)Q8NEZ5
IntAct (EBI)Q8NEZ5
FunCoupENSG00000167196
BioGRIDFBXO22
STRING (EMBL)FBXO22
ZODIACFBXO22
Ontologies - Pathways
QuickGOQ8NEZ5
Ontology : AmiGOprotein polyubiquitination  ubiquitin-protein transferase activity  ubiquitin-protein transferase activity  protein binding  nucleus  cytosol  cellular protein modification process  ubiquitin-dependent protein catabolic process  nucleocytoplasmic transport  cellular response to starvation  Z disc  positive regulation of proteasomal ubiquitin-dependent protein catabolic process  regulation of skeletal muscle fiber development  positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process  
Ontology : EGO-EBIprotein polyubiquitination  ubiquitin-protein transferase activity  ubiquitin-protein transferase activity  protein binding  nucleus  cytosol  cellular protein modification process  ubiquitin-dependent protein catabolic process  nucleocytoplasmic transport  cellular response to starvation  Z disc  positive regulation of proteasomal ubiquitin-dependent protein catabolic process  regulation of skeletal muscle fiber development  positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process  
NDEx NetworkFBXO22
Atlas of Cancer Signalling NetworkFBXO22
Wikipedia pathwaysFBXO22
Orthology - Evolution
OrthoDB26263
GeneTree (enSembl)ENSG00000167196
Phylogenetic Trees/Animal Genes : TreeFamFBXO22
HOVERGENQ8NEZ5
HOGENOMQ8NEZ5
Homologs : HomoloGeneFBXO22
Homology/Alignments : Family Browser (UCSC)FBXO22
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerFBXO22 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)FBXO22
dbVarFBXO22
ClinVarFBXO22
1000_GenomesFBXO22 
Exome Variant ServerFBXO22
ExAC (Exome Aggregation Consortium)FBXO22 (select the gene name)
Genetic variants : HAPMAP26263
Genomic Variants (DGV)FBXO22 [DGVbeta]
DECIPHERFBXO22 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisFBXO22 
Mutations
ICGC Data PortalFBXO22 
TCGA Data PortalFBXO22 
Broad Tumor PortalFBXO22
OASIS PortalFBXO22 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICFBXO22  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDFBXO22
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch FBXO22
DgiDB (Drug Gene Interaction Database)FBXO22
DoCM (Curated mutations)FBXO22 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)FBXO22 (select a term)
intoGenFBXO22
Cancer3DFBXO22(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609096   
Orphanet
MedgenFBXO22
Genetic Testing Registry FBXO22
NextProtQ8NEZ5 [Medical]
TSGene26263
GENETestsFBXO22
Target ValidationFBXO22
Huge Navigator FBXO22 [HugePedia]
snp3D : Map Gene to Disease26263
BioCentury BCIQFBXO22
ClinGenFBXO22
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD26263
Chemical/Pharm GKB GenePA28035
Clinical trialFBXO22
Miscellaneous
canSAR (ICR)FBXO22 (select the gene name)
Probes
Litterature
PubMed26 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineFBXO22
EVEXFBXO22
GoPubMedFBXO22
iHOPFBXO22
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Aug 1 17:01:02 CEST 2017

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