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FBXO25 (F-box protein 25)

Identity

Alias_namesF-box only protein 25
Alias_symbol (synonym)FBX25
Other alias
HGNC (Hugo) FBXO25
LocusID (NCBI) 26260
Atlas_Id 47354
Location 8p23.3  [Link to chromosome band 8p23]
Location_base_pair Starts at 406958 and ends at 477967 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
FBXO25 (8p23.3) / BET1L (11p15.5)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(8;11)(p23;p15) FBXO25/BET1L


External links

Nomenclature
HGNC (Hugo)FBXO25   13596
Cards
Entrez_Gene (NCBI)FBXO25  26260  F-box protein 25
AliasesFBX25
GeneCards (Weizmann)FBXO25
Ensembl hg19 (Hinxton)ENSG00000147364 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000147364 [Gene_View]  ENSG00000147364 [Sequence]  chr8:406958-477967 [Contig_View]  FBXO25 [Vega]
ICGC DataPortalENSG00000147364
TCGA cBioPortalFBXO25
AceView (NCBI)FBXO25
Genatlas (Paris)FBXO25
WikiGenes26260
SOURCE (Princeton)FBXO25
Genetics Home Reference (NIH)FBXO25
Genomic and cartography
GoldenPath hg38 (UCSC)FBXO25  -     chr8:406958-477967 +  8p23.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)FBXO25  -     8p23.3   [Description]    (hg19-Feb_2009)
GoldenPathFBXO25 - 8p23.3 [CytoView hg19]  FBXO25 - 8p23.3 [CytoView hg38]
Genome Data Viewer NCBIFBXO25 [Mapview hg19]  
OMIM609098   
Gene and transcription
Genbank (Entrez)AA316216 AB070270 AF174605 AF419858 AI223050
RefSeq transcript (Entrez)NM_012173 NM_183420 NM_183421
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)FBXO25
Alternative Splicing GalleryENSG00000147364
Gene ExpressionFBXO25 [ NCBI-GEO ]   FBXO25 [ EBI - ARRAY_EXPRESS ]   FBXO25 [ SEEK ]   FBXO25 [ MEM ]
Gene Expression Viewer (FireBrowse)FBXO25 [ Firebrowse - Broad ]
GenevisibleExpression of FBXO25 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)26260
GTEX Portal (Tissue expression)FBXO25
Human Protein AtlasENSG00000147364-FBXO25 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8TCJ0   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8TCJ0  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8TCJ0
Splice isoforms : SwissVarQ8TCJ0
PhosPhoSitePlusQ8TCJ0
Domains : Interpro (EBI)F-box-like_dom_sf    FBX25/32   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)FBXO25
DMDM Disease mutations26260
SuperfamilyQ8TCJ0
Human Protein Atlas [tissue]ENSG00000147364-FBXO25 [tissue]
Peptide AtlasQ8TCJ0
HPRD16439
IPIIPI00289939   IPI00374099   IPI00073356   IPI00908868   IPI00983237   
Protein Interaction databases
DIP (DOE-UCLA)Q8TCJ0
IntAct (EBI)Q8TCJ0
FunCoupENSG00000147364
BioGRIDFBXO25
STRING (EMBL)FBXO25
ZODIACFBXO25
Ontologies - Pathways
QuickGOQ8TCJ0
Ontology : AmiGOubiquitin ligase complex  actin binding  ubiquitin-protein transferase activity  nucleus  nucleus  nucleolus  protein ubiquitination  protein ubiquitination  protein ubiquitination  SCF ubiquitin ligase complex  
Ontology : EGO-EBIubiquitin ligase complex  actin binding  ubiquitin-protein transferase activity  nucleus  nucleus  nucleolus  protein ubiquitination  protein ubiquitination  protein ubiquitination  SCF ubiquitin ligase complex  
Pathways : KEGGFoxO signaling pathway   
NDEx NetworkFBXO25
Atlas of Cancer Signalling NetworkFBXO25
Wikipedia pathwaysFBXO25
Orthology - Evolution
OrthoDB26260
GeneTree (enSembl)ENSG00000147364
Phylogenetic Trees/Animal Genes : TreeFamFBXO25
HOGENOMQ8TCJ0
Homologs : HomoloGeneFBXO25
Homology/Alignments : Family Browser (UCSC)FBXO25
Gene fusions - Rearrangements
Fusion : MitelmanFBXO25/BET1L [8p23.3/11p15.5]  
Fusion : QuiverFBXO25
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerFBXO25 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)FBXO25
dbVarFBXO25
ClinVarFBXO25
1000_GenomesFBXO25 
Exome Variant ServerFBXO25
GNOMAD BrowserENSG00000147364
Varsome BrowserFBXO25
Genetic variants : HAPMAP26260
Genomic Variants (DGV)FBXO25 [DGVbeta]
DECIPHERFBXO25 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisFBXO25 
Mutations
ICGC Data PortalFBXO25 
TCGA Data PortalFBXO25 
Broad Tumor PortalFBXO25
OASIS PortalFBXO25 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICFBXO25  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DFBXO25
Mutations and Diseases : HGMDFBXO25
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutaselect FBXO25
DgiDB (Drug Gene Interaction Database)FBXO25
DoCM (Curated mutations)FBXO25 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)FBXO25 (select a term)
intoGenFBXO25
Cancer3DFBXO25 (select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609098   
Orphanet
DisGeNETFBXO25
MedgenFBXO25
Genetic Testing Registry FBXO25
NextProtQ8TCJ0 [Medical]
TSGene26260
GENETestsFBXO25
Open Targets GeneticsENSG00000147364  [validation]
snp3D : Map Gene to Disease26260
BioCentury BCIQFBXO25
ClinGenFBXO25
Clinical trials, drugs, therapy
Protein Interactions : CTD26260
Pharm GKB GenePA28038
Clinical trialFBXO25
Miscellaneous
canSAR (ICR)FBXO25 (select the gene name)
HarmonizomeFBXO25
DataMed IndexFBXO25
Probes
Litterature
PubMed23 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineFBXO25
EVEXFBXO25
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Sat Jul 11 19:48:41 CEST 2020

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