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FBXO3 (F-box protein 3)

Identity

Alias_namesF-box only protein 3
Alias_symbol (synonym)FBX3
FBA
Other alias
HGNC (Hugo) FBXO3
LocusID (NCBI) 26273
Atlas_Id 54315
Location 11p13  [Link to chromosome band 11p13]
Location_base_pair Starts at 33740944 and ends at 33774525 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
CD59 (11p13) / FBXO3 (11p13)KDM2A (11q13.2) / FBXO3 (11p13)NCOR1 (17p12) / FBXO3 (11p13)
RDH13 (19q13.42) / FBXO3 (11p13)CD59 11p13 / FBXO3 11p13KDM2A 11q13.2 / FBXO3 11p13
NCOR1 17p12 / FBXO3 11p13

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)FBXO3   13582
Cards
Entrez_Gene (NCBI)FBXO3  26273  F-box protein 3
AliasesFBA; FBX3
GeneCards (Weizmann)FBXO3
Ensembl hg19 (Hinxton)ENSG00000110429 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000110429 [Gene_View]  chr11:33740944-33774525 [Contig_View]  FBXO3 [Vega]
ICGC DataPortalENSG00000110429
TCGA cBioPortalFBXO3
AceView (NCBI)FBXO3
Genatlas (Paris)FBXO3
WikiGenes26273
SOURCE (Princeton)FBXO3
Genetics Home Reference (NIH)FBXO3
Genomic and cartography
GoldenPath hg38 (UCSC)FBXO3  -     chr11:33740944-33774525 -  11p13   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)FBXO3  -     11p13   [Description]    (hg19-Feb_2009)
EnsemblFBXO3 - 11p13 [CytoView hg19]  FBXO3 - 11p13 [CytoView hg38]
Mapping of homologs : NCBIFBXO3 [Mapview hg19]  FBXO3 [Mapview hg38]
OMIM609089   
Gene and transcription
Genbank (Entrez)AB209039 AF174595 AF176702 AK001943 AK123198
RefSeq transcript (Entrez)NM_012175 NM_033406
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)FBXO3
Cluster EST : UnigeneHs.406787 [ NCBI ]
CGAP (NCI)Hs.406787
Alternative Splicing GalleryENSG00000110429
Gene ExpressionFBXO3 [ NCBI-GEO ]   FBXO3 [ EBI - ARRAY_EXPRESS ]   FBXO3 [ SEEK ]   FBXO3 [ MEM ]
Gene Expression Viewer (FireBrowse)FBXO3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)26273
GTEX Portal (Tissue expression)FBXO3
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9UK99   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9UK99  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9UK99
Splice isoforms : SwissVarQ9UK99
PhosPhoSitePlusQ9UK99
Domaine pattern : Prosite (Expaxy)APAG (PS51087)    FBOX (PS50181)   
Domains : Interpro (EBI)ApaG_domain    F-box_dom    SMI1/KNR4-like_dom   
Domain families : Pfam (Sanger)DUF525 (PF04379)    F-box-like (PF12937)    SMI1_KNR4 (PF09346)   
Domain families : Pfam (NCBI)pfam04379    pfam12937    pfam09346   
Domain families : Smart (EMBL)FBOX (SM00256)  SMI1_KNR4 (SM00860)  
Conserved Domain (NCBI)FBXO3
DMDM Disease mutations26273
Blocks (Seattle)FBXO3
PDB (SRS)5HDW   
PDB (PDBSum)5HDW   
PDB (IMB)5HDW   
PDB (RSDB)5HDW   
Structural Biology KnowledgeBase5HDW   
SCOP (Structural Classification of Proteins)5HDW   
CATH (Classification of proteins structures)5HDW   
SuperfamilyQ9UK99
Human Protein AtlasENSG00000110429
Peptide AtlasQ9UK99
HPRD16433
IPIIPI00296789   IPI00472624   IPI00969390   IPI00478103   IPI00746271   IPI00985213   IPI00981558   IPI00910578   IPI00979398   IPI00977472   
Protein Interaction databases
DIP (DOE-UCLA)Q9UK99
IntAct (EBI)Q9UK99
FunCoupENSG00000110429
BioGRIDFBXO3
STRING (EMBL)FBXO3
ZODIACFBXO3
Ontologies - Pathways
QuickGOQ9UK99
Ontology : AmiGOubiquitin-protein transferase activity  protein binding  nucleoplasm  cytosol  proteolysis  protein ubiquitination  
Ontology : EGO-EBIubiquitin-protein transferase activity  protein binding  nucleoplasm  cytosol  proteolysis  protein ubiquitination  
NDEx NetworkFBXO3
Atlas of Cancer Signalling NetworkFBXO3
Wikipedia pathwaysFBXO3
Orthology - Evolution
OrthoDB26273
GeneTree (enSembl)ENSG00000110429
Phylogenetic Trees/Animal Genes : TreeFamFBXO3
HOVERGENQ9UK99
HOGENOMQ9UK99
Homologs : HomoloGeneFBXO3
Homology/Alignments : Family Browser (UCSC)FBXO3
Gene fusions - Rearrangements
Fusion : MitelmanKDM2A/FBXO3 [11q13.2/11p13]  [t(11;11)(p13;q13)]  
Fusion : MitelmanRDH13/FBXO3 [19q13.42/11p13]  [t(11;19)(p13;q13)]  
Fusion: TCGACD59 11p13 FBXO3 11p13 BRCA
Fusion: TCGAKDM2A 11q13.2 FBXO3 11p13 BRCA
Fusion: TCGANCOR1 17p12 FBXO3 11p13 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerFBXO3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)FBXO3
dbVarFBXO3
ClinVarFBXO3
1000_GenomesFBXO3 
Exome Variant ServerFBXO3
ExAC (Exome Aggregation Consortium)FBXO3 (select the gene name)
Genetic variants : HAPMAP26273
Genomic Variants (DGV)FBXO3 [DGVbeta]
DECIPHERFBXO3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisFBXO3 
Mutations
ICGC Data PortalFBXO3 
TCGA Data PortalFBXO3 
Broad Tumor PortalFBXO3
OASIS PortalFBXO3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICFBXO3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDFBXO3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch FBXO3
DgiDB (Drug Gene Interaction Database)FBXO3
DoCM (Curated mutations)FBXO3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)FBXO3 (select a term)
intoGenFBXO3
Cancer3DFBXO3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609089   
Orphanet
MedgenFBXO3
Genetic Testing Registry FBXO3
NextProtQ9UK99 [Medical]
TSGene26273
GENETestsFBXO3
Target ValidationFBXO3
Huge Navigator FBXO3 [HugePedia]
snp3D : Map Gene to Disease26273
BioCentury BCIQFBXO3
ClinGenFBXO3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD26273
Chemical/Pharm GKB GenePA28040
Clinical trialFBXO3
Miscellaneous
canSAR (ICR)FBXO3 (select the gene name)
Probes
Litterature
PubMed26 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineFBXO3
EVEXFBXO3
GoPubMedFBXO3
iHOPFBXO3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Mon Sep 18 13:53:14 CEST 2017

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