Atlas of Genetics and Cytogenetics in Oncology and Haematology


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FBXO32 (F-box protein 32)

Identity

Alias_namesF-box only protein 32
Alias_symbol (synonym)MAFbx
ATROGIN1
Fbx32
Other alias
HGNC (Hugo) FBXO32
LocusID (NCBI) 114907
Atlas_Id 46698
Location 8q24.13  [Link to chromosome band 8q24]
Location_base_pair Starts at 123497887 and ends at 123541253 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
ARRDC2 (19p13.11) / FBXO32 (8q24.13)FBXO32 (8q24.13) / AGGF1 (5q13.3)FBXO32 (8q24.13) / FBXO32 (8q24.13)
FBXO32 (8q24.13) / MYEOV (11q13.3)ITGA4 (2q31.3) / FBXO32 (8q24.13)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)FBXO32   16731
Cards
Entrez_Gene (NCBI)FBXO32  114907  F-box protein 32
AliasesFbx32; MAFbx
GeneCards (Weizmann)FBXO32
Ensembl hg19 (Hinxton)ENSG00000156804 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000156804 [Gene_View]  chr8:123497887-123541253 [Contig_View]  FBXO32 [Vega]
ICGC DataPortalENSG00000156804
TCGA cBioPortalFBXO32
AceView (NCBI)FBXO32
Genatlas (Paris)FBXO32
WikiGenes114907
SOURCE (Princeton)FBXO32
Genetics Home Reference (NIH)FBXO32
Genomic and cartography
GoldenPath hg38 (UCSC)FBXO32  -     chr8:123497887-123541253 -  8q24.13   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)FBXO32  -     8q24.13   [Description]    (hg19-Feb_2009)
EnsemblFBXO32 - 8q24.13 [CytoView hg19]  FBXO32 - 8q24.13 [CytoView hg38]
Mapping of homologs : NCBIFBXO32 [Mapview hg19]  FBXO32 [Mapview hg38]
OMIM606604   
Gene and transcription
Genbank (Entrez)AI077844 AJ420108 AK023391 AK056986 AK096904
RefSeq transcript (Entrez)NM_001242463 NM_058229 NM_148177
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)FBXO32
Cluster EST : UnigeneHs.403933 [ NCBI ]
CGAP (NCI)Hs.403933
Alternative Splicing GalleryENSG00000156804
Gene ExpressionFBXO32 [ NCBI-GEO ]   FBXO32 [ EBI - ARRAY_EXPRESS ]   FBXO32 [ SEEK ]   FBXO32 [ MEM ]
Gene Expression Viewer (FireBrowse)FBXO32 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)114907
GTEX Portal (Tissue expression)FBXO32
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ969P5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ969P5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ969P5
Splice isoforms : SwissVarQ969P5
PhosPhoSitePlusQ969P5
Domains : Interpro (EBI)F-box_dom   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)FBXO32
DMDM Disease mutations114907
Blocks (Seattle)FBXO32
SuperfamilyQ969P5
Human Protein AtlasENSG00000156804
Peptide AtlasQ969P5
HPRD05966
IPIIPI00056487   IPI00376505   IPI00981052   
Protein Interaction databases
DIP (DOE-UCLA)Q969P5
IntAct (EBI)Q969P5
FunCoupENSG00000156804
BioGRIDFBXO32
STRING (EMBL)FBXO32
ZODIACFBXO32
Ontologies - Pathways
QuickGOQ969P5
Ontology : AmiGOprotein polyubiquitination  ubiquitin-protein transferase activity  ubiquitin-protein transferase activity  protein binding  nucleoplasm  cytoplasm  cytosol  cytosol  response to denervation involved in regulation of muscle adaptation  protein ubiquitination  SCF ubiquitin ligase complex  Z disc  cellular response to dexamethasone stimulus  
Ontology : EGO-EBIprotein polyubiquitination  ubiquitin-protein transferase activity  ubiquitin-protein transferase activity  protein binding  nucleoplasm  cytoplasm  cytosol  cytosol  response to denervation involved in regulation of muscle adaptation  protein ubiquitination  SCF ubiquitin ligase complex  Z disc  cellular response to dexamethasone stimulus  
Pathways : KEGGFoxO signaling pathway   
NDEx NetworkFBXO32
Atlas of Cancer Signalling NetworkFBXO32
Wikipedia pathwaysFBXO32
Orthology - Evolution
OrthoDB114907
GeneTree (enSembl)ENSG00000156804
Phylogenetic Trees/Animal Genes : TreeFamFBXO32
HOVERGENQ969P5
HOGENOMQ969P5
Homologs : HomoloGeneFBXO32
Homology/Alignments : Family Browser (UCSC)FBXO32
Gene fusions - Rearrangements
Fusion Cancer (Beijing)ITGA4 [2q31.3]  -  FBXO32 [8q24.13]  [FUSC003449]
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerFBXO32 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)FBXO32
dbVarFBXO32
ClinVarFBXO32
1000_GenomesFBXO32 
Exome Variant ServerFBXO32
ExAC (Exome Aggregation Consortium)FBXO32 (select the gene name)
Genetic variants : HAPMAP114907
Genomic Variants (DGV)FBXO32 [DGVbeta]
DECIPHERFBXO32 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisFBXO32 
Mutations
ICGC Data PortalFBXO32 
TCGA Data PortalFBXO32 
Broad Tumor PortalFBXO32
OASIS PortalFBXO32 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICFBXO32  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDFBXO32
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch FBXO32
DgiDB (Drug Gene Interaction Database)FBXO32
DoCM (Curated mutations)FBXO32 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)FBXO32 (select a term)
intoGenFBXO32
Cancer3DFBXO32(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM606604   
Orphanet
MedgenFBXO32
Genetic Testing Registry FBXO32
NextProtQ969P5 [Medical]
TSGene114907
GENETestsFBXO32
Target ValidationFBXO32
Huge Navigator FBXO32 [HugePedia]
snp3D : Map Gene to Disease114907
BioCentury BCIQFBXO32
ClinGenFBXO32
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD114907
Chemical/Pharm GKB GenePA28043
Clinical trialFBXO32
Miscellaneous
canSAR (ICR)FBXO32 (select the gene name)
Probes
Litterature
PubMed50 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineFBXO32
EVEXFBXO32
GoPubMedFBXO32
iHOPFBXO32
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 19:08:04 CEST 2017

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