Atlas of Genetics and Cytogenetics in Oncology and Haematology


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FBXO4 (F-box protein 4)

Identity

Alias_namesF-box only protein 4
Alias_symbol (synonym)FBX4
Other alias
HGNC (Hugo) FBXO4
LocusID (NCBI) 26272
Atlas_Id 50376
Location 5p13.1  [Link to chromosome band 5p13]
Location_base_pair Starts at 41925354 and ends at 41941672 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
NUP210 (3p25.1) / FBXO4 (5p13.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)FBXO4   13583
Cards
Entrez_Gene (NCBI)FBXO4  26272  F-box protein 4
AliasesFBX4
GeneCards (Weizmann)FBXO4
Ensembl hg19 (Hinxton)ENSG00000151876 [Gene_View]  chr5:41925354-41941672 [Contig_View]  FBXO4 [Vega]
Ensembl hg38 (Hinxton)ENSG00000151876 [Gene_View]  chr5:41925354-41941672 [Contig_View]  FBXO4 [Vega]
ICGC DataPortalENSG00000151876
TCGA cBioPortalFBXO4
AceView (NCBI)FBXO4
Genatlas (Paris)FBXO4
WikiGenes26272
SOURCE (Princeton)FBXO4
Genetics Home Reference (NIH)FBXO4
Genomic and cartography
GoldenPath hg19 (UCSC)FBXO4  -     chr5:41925354-41941672 +  5p13.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)FBXO4  -     5p13.1   [Description]    (hg38-Dec_2013)
EnsemblFBXO4 - 5p13.1 [CytoView hg19]  FBXO4 - 5p13.1 [CytoView hg38]
Mapping of homologs : NCBIFBXO4 [Mapview hg19]  FBXO4 [Mapview hg38]
OMIM609090   
Gene and transcription
Genbank (Entrez)AF129534 AF176703 AK001003 AK024075 AU143782
RefSeq transcript (Entrez)NM_001297437 NM_012176 NM_033484
RefSeq genomic (Entrez)NC_000005 NC_018916 NT_006576 NW_004929321
Consensus coding sequences : CCDS (NCBI)FBXO4
Cluster EST : UnigeneHs.165575 [ NCBI ]
CGAP (NCI)Hs.165575
Alternative Splicing GalleryENSG00000151876
Gene ExpressionFBXO4 [ NCBI-GEO ]   FBXO4 [ EBI - ARRAY_EXPRESS ]   FBXO4 [ SEEK ]   FBXO4 [ MEM ]
Gene Expression Viewer (FireBrowse)FBXO4 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)26272
GTEX Portal (Tissue expression)FBXO4
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9UKT5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9UKT5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9UKT5
Splice isoforms : SwissVarQ9UKT5
PhosPhoSitePlusQ9UKT5
Domaine pattern : Prosite (Expaxy)FBOX (PS50181)   
Domains : Interpro (EBI)F-box_dom   
Domain families : Pfam (Sanger)F-box (PF00646)   
Domain families : Pfam (NCBI)pfam00646   
Domain families : Smart (EMBL)FBOX (SM00256)  
Conserved Domain (NCBI)FBXO4
DMDM Disease mutations26272
Blocks (Seattle)FBXO4
PDB (SRS)3L2O    3L82   
PDB (PDBSum)3L2O    3L82   
PDB (IMB)3L2O    3L82   
PDB (RSDB)3L2O    3L82   
Structural Biology KnowledgeBase3L2O    3L82   
SCOP (Structural Classification of Proteins)3L2O    3L82   
CATH (Classification of proteins structures)3L2O    3L82   
SuperfamilyQ9UKT5
Human Protein AtlasENSG00000151876
Peptide AtlasQ9UKT5
HPRD09949
IPIIPI00073357   IPI00245689   IPI00385993   IPI00964657   IPI00969074   IPI00967456   
Protein Interaction databases
DIP (DOE-UCLA)Q9UKT5
IntAct (EBI)Q9UKT5
FunCoupENSG00000151876
BioGRIDFBXO4
STRING (EMBL)FBXO4
ZODIACFBXO4
Ontologies - Pathways
QuickGOQ9UKT5
Ontology : AmiGOubiquitin ligase complex  protein polyubiquitination  protein polyubiquitination  telomere maintenance  ubiquitin-protein transferase activity  ubiquitin-protein transferase activity  ubiquitin-protein transferase activity  protein binding  cytosol  ubiquitin-dependent protein catabolic process  protein ubiquitination  SCF ubiquitin ligase complex  SCF-dependent proteasomal ubiquitin-dependent protein catabolic process  positive regulation of protein ubiquitination  protein homodimerization activity  
Ontology : EGO-EBIubiquitin ligase complex  protein polyubiquitination  protein polyubiquitination  telomere maintenance  ubiquitin-protein transferase activity  ubiquitin-protein transferase activity  ubiquitin-protein transferase activity  protein binding  cytosol  ubiquitin-dependent protein catabolic process  protein ubiquitination  SCF ubiquitin ligase complex  SCF-dependent proteasomal ubiquitin-dependent protein catabolic process  positive regulation of protein ubiquitination  protein homodimerization activity  
Pathways : KEGGUbiquitin mediated proteolysis   
NDEx NetworkFBXO4
Atlas of Cancer Signalling NetworkFBXO4
Wikipedia pathwaysFBXO4
Orthology - Evolution
OrthoDB26272
GeneTree (enSembl)ENSG00000151876
Phylogenetic Trees/Animal Genes : TreeFamFBXO4
HOVERGENQ9UKT5
HOGENOMQ9UKT5
Homologs : HomoloGeneFBXO4
Homology/Alignments : Family Browser (UCSC)FBXO4
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerFBXO4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)FBXO4
dbVarFBXO4
ClinVarFBXO4
1000_GenomesFBXO4 
Exome Variant ServerFBXO4
ExAC (Exome Aggregation Consortium)FBXO4 (select the gene name)
Genetic variants : HAPMAP26272
Genomic Variants (DGV)FBXO4 [DGVbeta]
DECIPHER (Syndromes)5:41925354-41941672  ENSG00000151876
CONAN: Copy Number AnalysisFBXO4 
Mutations
ICGC Data PortalFBXO4 
TCGA Data PortalFBXO4 
Broad Tumor PortalFBXO4
OASIS PortalFBXO4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICFBXO4  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDFBXO4
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch FBXO4
DgiDB (Drug Gene Interaction Database)FBXO4
DoCM (Curated mutations)FBXO4 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)FBXO4 (select a term)
intoGenFBXO4
Cancer3DFBXO4(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609090   
Orphanet
MedgenFBXO4
Genetic Testing Registry FBXO4
NextProtQ9UKT5 [Medical]
TSGene26272
GENETestsFBXO4
Huge Navigator FBXO4 [HugePedia]
snp3D : Map Gene to Disease26272
BioCentury BCIQFBXO4
ClinGenFBXO4
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD26272
Chemical/Pharm GKB GenePA28044
Clinical trialFBXO4
Miscellaneous
canSAR (ICR)FBXO4 (select the gene name)
Probes
Litterature
PubMed32 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineFBXO4
EVEXFBXO4
GoPubMedFBXO4
iHOPFBXO4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Thu Mar 30 15:01:00 CEST 2017

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