FBXO42 (F-box protein 42)

2003-05-01  

Identity

HGNC
LOCATION
1p36.13
LOCUSID
ALIAS
Fbx42,JFK
FUSION GENES

Other Information

Locus ID:

NCBI: 54455
MIM: 609109
HGNC: 29249
Ensembl: ENSG00000037637

Variants:

dbSNP: 54455
ClinVar: 54455
TCGA: ENSG00000037637
COSMIC: FBXO42

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000037637ENST00000375592Q6P3S6
ENSG00000037637ENST00000375592A0A024QZB0
ENSG00000037637ENST00000444116X6RKU3
ENSG00000037637ENST00000456164X6RKU3

Expression (GTEx)

0
5
10
15
20
25
30

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
195093322009JFK, a Kelch domain-containing F-box protein, links the SCF complex to p53 regulation.28
257926012015SCF(JFK) is a bona fide E3 ligase for ING4 and a potent promoter of the angiogenesis and metastasis of breast cancer.10
211270742011Substrate phosphorylation and feedback regulation in JFK-promoted p53 destabilization.6
240636882013Genetic analysis of the FBXO42 gene in Chinese Han patients with Parkinson's disease.0

Citation

Dessen P

FBXO42 (F-box protein 42)

Atlas Genet Cytogenet Oncol Haematol. 2003-05-01

Online version: http://atlasgeneticsoncology.org/gene/41064/fbxo42