FBXO43 (F-box protein 43)

2007-04-01  

Identity

HGNC
FBXO43
LOCATION
8q22.2
LOCUSID
286151
ALIAS
EMI2,ERP1,FBX43

Other Information

Locus ID:

NCBI: 286151
MIM: 609110
HGNC: 28521
Ensembl: ENSG00000156509

Variants:

dbSNP: 286151
ClinVar: 286151
TCGA: ENSG00000156509
COSMIC: FBXO43

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000156509ENST00000428847Q4G163
ENSG00000156509ENST00000517806E5RHI5

Expression (GTEx)

0
5
10
15
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Oocyte meiosisKEGGko04114
Oocyte meiosisKEGGhsa04114

Protein levels (Protein atlas)

Not detected
Low
Medium
High
N/A

References

Pubmed IDYearTitleCitations
185507952008Cdc2 and Mos regulate Emi2 stability to promote the meiosis I-meiosis II transition.12
308782522019A novel homozygous FBXO43 mutation associated with male infertility and teratozoospermia in a consanguineous Chinese family.0

Citation

Dessen P

FBXO43 (F-box protein 43)

Atlas Genet Cytogenet Oncol Haematol. 2007-04-01

Online version: http://atlasgeneticsoncology.org/gene/47237/fbxo43